A census of human cancer genes
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T. Hubbard | M. Stratton | N. Rahman | T. Down | P. Futreal | L. Coin | M. Marshall | R. Wooster | Michael R. Stratton | M. Stratton
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[2] G. Cooper,et al. Transforming activity of human tumor DNAs. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[3] Eugenio Santos,et al. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene , 1982, Nature.
[4] Cori Bargmann,et al. Mechanism of activation of a human oncogene , 1982, Nature.
[5] B. Vogelstein,et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. , 1990, Cancer research.
[6] P. Humphrey,et al. Structural alterations of the epidermal growth factor receptor gene in human gliomas. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[7] N. Copeland,et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer , 1993, Cell.
[8] Robin J. Leach,et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer , 1993, Cell.
[9] Bert Vogelstein,et al. Hypermutability and mismatch repair deficiency in RER+ tumor cells , 1993, Cell.
[10] C. Carcano,et al. Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A , 1993, Molecular and cellular biology.
[11] M. Skolnick,et al. BRCA1 mutations in primary breast and ovarian carcinomas. , 1994, Science.
[12] M. Skolnick,et al. A cell cycle regulator potentially involved in genesis of many tumor types. , 1994, Science.
[13] J. Herman,et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers , 1995, Nature Medicine.
[14] M. Lovett,et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. , 1995, Science.
[15] C. Croce,et al. The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers , 1996, Cell.
[16] S Gill,et al. The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene. , 1996, Human molecular genetics.
[17] Sheila Seal,et al. BRCA2 mutations in primary breast and ovarian cancers , 1996, Nature Genetics.
[18] L. Mulligan,et al. Mutations of the RET proto‐oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and Hirschsprung disease , 1997, Human mutation.
[19] H. Ostrer,et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC , 1997, Nature Genetics.
[20] M. Loda,et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. , 1997, Cancer research.
[21] M. Wigler,et al. PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer , 1997, Science.
[22] W. Marston Linehan,et al. Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas , 1998, Nature Genetics.
[23] R. Richards,et al. Fragile sites still breaking. , 1998, Trends in genetics : TIG.
[24] S. Hirota,et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. , 1998, Science.
[25] M. Stratton,et al. A serine/threonine kinase gene defective in Peutz–Jeghers syndrome , 1998, Nature.
[26] K. Kinzler,et al. Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers. , 1999, Cancer research.
[27] B. Spiegelman,et al. PAX8-PPARγ1 Fusion in Oncogene Human Thyroid Carcinoma , 2000 .
[28] A. Bednarek,et al. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. , 2000, Cancer research.
[29] C. Stratakis,et al. Mutations of the gene encoding the protein kinase A type I-α regulatory subunit in patients with the Carney complex , 2000, Nature Genetics.
[30] Victor E. Velculescu,et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis , 2001, Nature Genetics.
[31] M. Cleary,et al. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins , 2001, Oncogene.
[32] G. Thomas,et al. Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. , 2001, Human molecular genetics.
[33] J. Griffin,et al. The roles of FLT3 in hematopoiesis and leukemia. , 2002, Blood.
[34] Nazneen Rahman,et al. Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations , 2002, Nature Genetics.
[35] S. Baylin,et al. Altered methylation patterns in cancer cell genomes: cause or consequence? , 2002, Cancer cell.
[36] Y. Nikiforov. RET/PTC rearrangement in thyroid tumors , 2002, Endocrine pathology.
[37] A. Duval,et al. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. , 2002, Cancer research.
[38] David Sidransky,et al. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. , 2002, Cancer research.
[39] P. Sorensen,et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. , 2002, Cancer cell.
[40] Shih-Jen Hwang,et al. Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer risk. , 2003, American journal of human genetics.
[41] Samuel Singer,et al. PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors , 2003, Science.