Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells

[1]  A. Arneodo,et al.  Chromosome territories have a highly nonspherical morphology and nonrandom positioning , 2007, Chromosome Research.

[2]  Cameron S. Osborne,et al.  Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh , 2007, PLoS biology.

[3]  Tom Misteli,et al.  Spatial genome organization in the formation of chromosomal translocations. , 2007, Seminars in cancer biology.

[4]  Tom Misteli,et al.  Cell biology: Chromosome territories , 2007, Nature.

[5]  G. Kreth,et al.  Chromosome arrangement and nuclear architecture but not centromeric sequences are conserved between Arabidopsis thaliana and Arabidopsis lyrata. , 2006, The Plant journal : for cell and molecular biology.

[6]  M. Cornforth,et al.  Perspectives on the formation of radiation-induced exchange aberrations. , 2006, DNA repair.

[7]  Carol J. Bult,et al.  Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence , 2006, The Journal of cell biology.

[8]  F. Stillinger,et al.  Some Observations on the Random Packing of Hard Ellipsoids , 2006 .

[9]  A. Pombo,et al.  Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations , 2006, PLoS biology.

[10]  I. Sánchez,et al.  Chromosome territory positioning of conserved homologous chromosomes in different primate species , 2006, Chromosoma.

[11]  Roland Eils,et al.  Local gene density predicts the spatial position of genetic loci in the interphase nucleus. , 2005, Experimental cell research.

[12]  Wendy A Bickmore,et al.  Chromatin organization in the mammalian nucleus. , 2005, International review of cytology.

[13]  Thomas Cremer,et al.  The architecture of chicken chromosome territories changes during differentiation , 2004, BMC Cell Biology.

[14]  Nick Gilbert,et al.  Chromatin Architecture of the Human Genome Gene-Rich Domains Are Enriched in Open Chromatin Fibers , 2004, Cell.

[15]  M. Vázquez,et al.  Chromosome spatial clustering inferred from radiogenic aberrations , 2004, International journal of radiation biology.

[16]  Tom Misteli,et al.  Tissue-specific spatial organization of genomes , 2004, Genome Biology.

[17]  F. Alt,et al.  Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. , 2004, Genes & development.

[18]  F. Alt,et al.  Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. , 2004, Genes & development.

[19]  T. Misteli,et al.  Spatial genome organization. , 2004, Experimental cell research.

[20]  C Cremer,et al.  Radial arrangement of chromosome territories in human cell nuclei: a computer model approach based on gene density indicates a probabilistic global positioning code. , 2004, Biophysical journal.

[21]  F. Stillinger,et al.  Improving the Density of Jammed Disordered Packings Using Ellipsoids , 2004, Science.

[22]  S. Jackson Faculty Opinions recommendation of Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. , 2004 .

[23]  Wendy A. Bickmore,et al.  The Radial Positioning of Chromatin Is Not Inherited through Mitosis but Is Established De Novo in Early G1 , 2004, Current Biology.

[24]  J. Aten,et al.  Dynamics of DNA Double-Strand Breaks Revealed by Clustering of Damaged Chromosome Domains , 2004, Science.

[25]  W. Bickmore,et al.  Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population , 2004, Chromosome Research.

[26]  T. Cremer,et al.  Inheritance of gene density–related higher order chromatin arrangements in normal and tumor cell nuclei , 2003, The Journal of cell biology.

[27]  M. Vázquez,et al.  Chromosomes are predominantly located randomly with respect to each other in interphase human cells , 2002, The Journal of cell biology.

[28]  Tom Misteli,et al.  Chromosome positioning in the interphase nucleus. , 2002, Trends in cell biology.

[29]  Mariel Vazquez,et al.  Radiation-induced chromosome aberrations: insights gained from biophysical modeling. , 2002, BioEssays : news and reviews in molecular, cellular and developmental biology.

[30]  T. Cremer,et al.  Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[31]  T Misteli,et al.  Functional architecture in the cell nucleus. , 2001, The Biochemical journal.

[32]  T. Cremer,et al.  Chromosome territories, nuclear architecture and gene regulation in mammalian cells , 2001, Nature Reviews Genetics.

[33]  C Cremer,et al.  Chromosome territories, interchromatin domain compartment, and nuclear matrix: an integrated view of the functional nuclear architecture. , 2000, Critical reviews in eukaryotic gene expression.

[34]  L. Donehower,et al.  Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours , 1992, Nature.

[35]  Y. Hochberg A sharper Bonferroni procedure for multiple tests of significance , 1988 .

[36]  A. Hope A Simplified Monte Carlo Significance Test Procedure , 1968 .