INSEL: an in silico method for optimizing and exploring biorecognition assays.

A practical in silico method for optimizing and exploring biointeraction-based events is developed.

[1]  P. Yager,et al.  A rapid diffusion immunoassay in a T-sensor , 2001, Nature Biotechnology.

[2]  Umaporn Uawisetwathana,et al.  Development of antibody array for simultaneous detection of foodborne pathogens. , 2009, Biosensors & bioelectronics.

[3]  Sergi Morais,et al.  DNA microarraying on compact disc surfaces. Application to the analysis of single nucleotide polymorphisms in Plum pox virus. , 2006, Chemical communications.

[4]  Mary Lundeberg,et al.  Engaging Students in Molecular Biology via Case-Based Learning , 2012, Science.

[5]  E. Marcotte,et al.  A flaw in the typical evaluation scheme for pair-input computational predictions , 2012, Nature Methods.

[6]  E. Work,et al.  Laboratory techniques in biochemistry and molecular biology , 1969 .

[7]  Á. Maquieira,et al.  Modeling of the role of conformational dynamics in kinetics of the antigen-antibody interaction in heterogeneous phase. , 2012, The journal of physical chemistry. B.

[8]  Luis A Tortajada-Genaro,et al.  Multiplexed microimmunoassays on a digital versatile disk. , 2009, Analytical chemistry.

[9]  Huang-Hao Yang,et al.  A simple and ultrasensitive electrochemical DNA biosensor based on DNA concatamers. , 2011, Chemical communications.

[10]  David Juncker,et al.  Taguchi design-based optimization of sandwich immunoassay microarrays for detecting breast cancer biomarkers. , 2011, Analytical chemistry.

[11]  B. Honig,et al.  Structure-based prediction of protein-protein interactions on a genome-wide scale , 2012, Nature.

[12]  Singiresu S. Rao Engineering Optimization : Theory and Practice , 2010 .

[13]  Taisun Kim,et al.  9G DNAChip: a platform for the efficient detection of proteins. , 2011, Chemical communications.

[14]  Xin Sheng Zhao,et al.  Kinetics and dynamics of DNA hybridization. , 2011, Accounts of chemical research.

[15]  M. Zavolan,et al.  A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets , 2013, Nature Methods.

[16]  Afshin Mashadi-Hossein,et al.  Concentration gradient immunoassay. 2. Computational modeling for analysis and optimization. , 2007, Analytical chemistry.

[17]  V. Sondak,et al.  In vivo and in silico pharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma. , 2013, Molecular pharmaceutics.

[18]  M. Barboiu,et al.  Multilayer lectin-glyconanoparticles architectures for QCM enhanced detection of sugar-protein interaction. , 2013, Chemical communications.

[19]  S. Rüdiger,et al.  Studying protein-protein interactions using peptide arrays. , 2011, Chemical Society reviews.

[20]  M. Calleja,et al.  Biosensors based on nanomechanical systems. , 2013, Chemical Society reviews.

[21]  Srinivas Tummala,et al.  Emerging technologies supporting chemical process R&D and their increasing impact on productivity in the pharmaceutical industry. , 2006, Chemical reviews.

[22]  O Shoval,et al.  Evolutionary Trade-Offs, Pareto Optimality, and the Geometry of Phenotype Space , 2012, Science.