Existence of Similar Leptospira Serovars among Dog Keepers and Their Respective Dogs in Mwanza, Tanzania, the Need for a One Health Approach to Control Measures

This study investigated seroepidemiology of Leptospira serovars among the dog keepers and their dogs in the city of Mwanza, Tanzania. A total of 205 dog keepers and 414 dogs were tested for Leptospira antibodies using a microscopic agglutination test (MAT). The median age of the dog keepers was 26 (inter quartile range (IQR): 17–40) years and median duration of keeping dogs was 36 (IQR: 24–120) months. The seropositivity of Leptospira antibodies was (33/205 (16.1%, 95% CI: 11.0–21.1) among dog keepers and (66/414 (15.9%, 95% CI: 12.4–19.4) among dogs, p = 0.4745. Among the serovars tested (Sokoine, Grippotyphosa, Kenya, Pomona and Hebdomadis), the most prevalent serovar was Sokoine in both dog keepers and their dogs (93.9% (31/33) vs. and 65.1% (43/66), p = 0.009). Thirty-one out of thirty-three seropositive dog keepers (93.9%) had dogs positive for Leptospira antibodies with 28 (84.9%) having similar serovars with their respective seropositive dogs. Having tertiary education (AOR: 0.24, 95% CI: 0.07–0.84, p = 0.026) independently protected individuals from being Leptospira seropositive. More than three quarters of dog keepers had similar serovars as their dogs, necessitating one health approach to control measures in endemic areas.

[1]  Population Distribution by Age and Sex , 2021, Encyclopedia of Gerontology and Population Aging.

[2]  M. Heinemann,et al.  Seroprevalence and incidence of Leptospira spp. in domestic dogs in the Southeast region of São Paulo State, Brazil , 2020 .

[3]  J. Wagenaar,et al.  Leptospira infection and shedding in dogs in Thailand , 2020, BMC Veterinary Research.

[4]  Khamisah Awang Lukman,et al.  Occupational Determinants of Leptospirosis among Urban Service Workers , 2020, International journal of environmental research and public health.

[5]  E. Fèvre,et al.  Seroprevalence and associated risk factors of leptospirosis in slaughter pigs; a neglected public health risk, western Kenya , 2019, BMC Veterinary Research.

[6]  G. Mgode,et al.  Leptospirosis in sugarcane plantation and fishing communities in Kagera northwestern Tanzania , 2019, PLoS neglected tropical diseases.

[7]  C. Levy,et al.  Despite high‐risk exposures, no evidence of zoonotic transmission during a canine outbreak of leptospirosis , 2019, Zoonoses and public health.

[8]  M. Amaku,et al.  Seroprevalence of Leptospira spp infection and its risk factors among domestic dogs in Bogotá, Colombia , 2018, Veterinary and animal science.

[9]  M. R.,et al.  Seroprevalence of canine leptospirosis, in Urban and Periurban, Morogoro, Tanzania , 2018, African Journal of Microbiology Research.

[10]  G. Mgode,et al.  Seropositivity of Brucella spp. and Leptospira spp. antibodies among abattoir workers and meat vendors in the city of Mwanza, Tanzania: A call for one health approach control strategies , 2018, PLoS neglected tropical diseases.

[11]  A. Conan,et al.  Leptospira Seroprevalence in Domestic Dogs and Cats on the Caribbean Island of Saint Kitts , 2017, Veterinary medicine international.

[12]  C. Goarant.  Leptospirosis: risk factors and management challenges in developing countries , 2016, Research and reports in tropical medicine.

[13]  K. J. Allan.  Leptospirosis in northern Tanzania: exploring the role of rodents and ruminant livestock in a neglected public health problem , 2016 .

[14]  H. Leirs,et al.  Leptospira Serovars for Diagnosis of Leptospirosis in Humans and Animals in Africa: Common Leptospira Isolates and Reservoir Hosts , 2015, PLoS neglected tropical diseases.

[15]  A. Ko,et al.  Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years , 2015, PLoS neglected tropical diseases.

[16]  A. Ko,et al.  Global Morbidity and Mortality of Leptospirosis: A Systematic Review , 2015, PLoS neglected tropical diseases.

[17]  R. Kazwala,et al.  Predominant Leptospiral Serogroups Circulating among Humans, Livestock and Wildlife in Katavi-Rukwa Ecosystem, Tanzania , 2015, PLoS neglected tropical diseases.

[18]  Shabani K. Muller.  Molecular epidemiology of Leptospira species among Agropastoral communities living in Katavi-Rukwa ecosystem, Tanzania , 2015 .

[19]  M. Bahari,et al.  Prevalence of leptospirosis and toxoplasmosis: a study of rodents and shrews in cultivated and fallow land, Morogoro rural district, Tanzania. , 2014, Tanzania journal of health research.

[20]  G. Mhamphi,et al.  Leptospira infections in freshwater fish in Morogoro Tanzania: a hidden public health threat. , 2014, Tanzania journal of health research.

[21]  R. Hartskeerl,et al.  Leptospirosis Serodiagnosis by the Microscopic Agglutination Test , 2014, Current protocols in microbiology.

[22]  F. Pagés,et al.  Human Leptospirosis on Reunion Island: Past and Current Burden , 2014, International journal of environmental research and public health.

[23]  J. Crump,et al.  Estimating Leptospirosis Incidence Using Hospital-Based Surveillance and a Population-Based Health Care Utilization Survey in Tanzania , 2013, PLoS neglected tropical diseases.

[24]  Yongwimon Lenbury,et al.  Document heading doi : Modeling seasonal leptospirosis transmission and its association with rainfall and temperature in Thailand using time-series and ARIMAX analyses , 2012 .

[25]  R. Gholam,et al.  Detection of leptospiral antibodies by microscopic agglutination test in north-east of Iran. , 2011, Asian Pacific Journal of Tropical Biomedicine.

[26]  H. Langoni,et al.  Interactions between environment, wild animals and human leptospirosis , 2011 .

[27]  Sally J. Cutler,et al.  Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World , 2010, Emerging infectious diseases.

[28]  A. Shriram,et al.  Leptospirosis: an emerging global public health problem , 2008, Journal of Biosciences.

[29]  K. Stark,et al.  Leptospirosis in Germany, 1962–2003 , 2005, Emerging infectious diseases.

[30]  J. Prescott,et al.  Resurgence of leptospirosis in dogs in Ontario: recent findings. , 2002, The Canadian veterinary journal = La revue veterinaire canadienne.

[31]  G. Mgode,et al.  Leptospirosis in animals and humans in selected areas of Tanzania , 1997 .

[32]  B. Babudieri.  ANIMAL RESERVOIRS OF LEPTOSPIRES , 1958, Annals of the New York Academy of Sciences.

[33]  H. Schlossberger,et al.  Leptospirosis in Germany. , 1938 .