Novel Nanosensors for Rapid Analysis of Telomerase Activity
暂无分享,去创建一个
Jan Grimm | Ralph Weissleder | Lee Josephson | R. Weissleder | L. Josephson | J. Grimm | J. Perez | J Manuel Perez | J. Perez
[1] Ralph Weissleder,et al. Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. , 2003, The New England journal of medicine.
[2] Ralph Weissleder,et al. Magnetic sensors for protease assays. , 2003, Angewandte Chemie.
[3] A. Zeiher,et al. Regulation of telomerase activity and anti‐apoptotic function by protein–protein interaction and phosphorylation , 2003, FEBS letters.
[4] Hidetoshi Sato,et al. A rapid biosensor chip assay for measuring of telomerase activity using surface plasmon resonance. , 2003, Nucleic acids research.
[5] L. Gong,et al. Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation. , 2003, World journal of gastroenterology.
[6] M. Blasco,et al. Massive Telomere Loss Is an Early Event of DNA Damage-induced Apoptosis* , 2003, The Journal of Biological Chemistry.
[7] M. Blasco,et al. Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation , 2003, The EMBO journal.
[8] Henning Wege,et al. SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. , 2002, Nucleic acids research.
[9] R. DePinho,et al. Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. , 2003, Genes & development.
[10] D. Corey,et al. Telomerase inhibitors: a new option for chemotherapy. , 2003, Advances in cancer research.
[11] N. Sato,et al. Telomerase as a new target for pancreatic cancer treatment. , 2002, Journal of hepato-biliary-pancreatic surgery.
[12] L. Chin,et al. Telomere dysfunction provokes regional amplification and deletion in cancer genomes. , 2002, Cancer cell.
[13] Ralph Weissleder,et al. Magnetic relaxation switches capable of sensing molecular interactions , 2002, Nature Biotechnology.
[14] Shunqing Xu,et al. Bioluminescent method for detecting telomerase activity. , 2002, Clinical chemistry.
[15] L. Guillou,et al. Telomerase activity and hTERT mRNA expression can be heterogeneous and does not correlate with telomere length in soft tissue sarcomas , 2002, International journal of cancer.
[16] Ralph Weissleder,et al. DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents. , 2002, Journal of the American Chemical Society.
[17] A. Schnapp,et al. A highly selective telomerase inhibitor limiting human cancer cell proliferation , 2001, The EMBO journal.
[18] J. Kim,et al. Protein kinase C modulates telomerase activity in human cervical cancer cells , 2001, Experimental & Molecular Medicine.
[19] Ralph Weissleder,et al. Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. , 2001, Angewandte Chemie.
[20] Kebin Liu,et al. Cutting Edge: Telomerase Activation in Human T Lymphocytes Does Not Require Increase in Telomerase Reverse Transcriptase (hTERT) Protein But Is Associated with hTERT Phosphorylation and Nuclear Translocation , 2001, The Journal of Immunology.
[21] Lynda Chin,et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice , 2000, Nature.
[22] T. Pandita,et al. Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase , 2000, Current Biology.
[23] Ralph Weissleder,et al. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells , 2000, Nature Biotechnology.
[24] R. Weil,et al. Limitations on the quantitative determination of telomerase activity by the electrophoretic and ELISA based TRAP assays. , 2000, Clinica chimica acta; international journal of clinical chemistry.
[25] R. DePinho,et al. A critical role for telomeres in suppressing and facilitating carcinogenesis. , 2000, Current opinion in genetics & development.
[26] K. Dhaene,et al. Absence of telomerase activity and telomerase catalytic subunit mRNA in melanocyte cultures , 2000, British Journal of Cancer.
[27] D. Corey,et al. Telomerase inhibition by peptide nucleic acids reverses `immortality' of transformed human cells , 1999, Oncogene.
[28] P. Iversen,et al. The cytotoxic effects of single-stranded telomere mimics on OMA-BL1 cells. , 1999, Experimental cell research.
[29] M. Tsuchiya,et al. Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro. , 1999, Biochemistry.
[30] K. Shigemasa,et al. Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines. , 1999, European journal of cancer.
[31] S. Do,et al. Akt Protein Kinase Enhances Human Telomerase Activity through Phosphorylation of Telomerase Reverse Transcriptase Subunit* , 1999, The Journal of Biological Chemistry.
[32] A. Cheng,et al. Polymerase Chain Reaction‐based Enzyme Immunoassay for Quantitation of Telomerase Activity: Application to Colorectal Cancers† , 1999, Japanese journal of cancer research : Gann.
[33] He Li,et al. Telomerase Is Controlled by Protein Kinase Cα in Human Breast Cancer Cells* , 1998, The Journal of Biological Chemistry.
[34] D. Lackey. A homogeneous chemiluminescent assay for telomerase. , 1998, Analytical biochemistry.
[35] S. Capaccioli,et al. Rapid, quantitative nonisotopic assay for telomerase activity in human tumors. , 1998, Clinical chemistry.
[36] D. Corey,et al. Inhibition of human telomerase by 2'-O-methyl-RNA. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[37] S. Neidle,et al. 1,4- and 2,6-disubstituted amidoanthracene-9,10-dione derivatives as inhibitors of human telomerase. , 1998, Journal of medicinal chemistry.
[38] R. Weinberg,et al. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase , 1998, Oncogene.
[39] S. Benchimol,et al. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span , 1998, Current Biology.
[40] Bas van Steensel,et al. TRF2 Protects Human Telomeres from End-to-End Fusions , 1998, Cell.
[41] M. Falchetti,et al. Increased sensitivity and reproducibility of TRAP assay by avoiding direct primers interaction. , 1998, Nucleic acids research.
[42] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[43] C. Greider. Telomerase activity, cell proliferation, and cancer. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[44] H. Li,et al. Protein Phosphatase 2A Inhibits Nuclear Telomerase Activity in Human Breast Cancer Cells* , 1997, The Journal of Biological Chemistry.
[45] Nam W. Kim,et al. Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP) , 1997, Nucleic Acids Res..
[46] P. Iversen,et al. A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of Burkitt's lymphoma cells in vitro and in vivo. , 1997, Toxicology and applied pharmacology.
[47] J. Shay,et al. A survey of telomerase activity in human cancer. , 1997, European journal of cancer.
[48] Bas van Steensel,et al. Control of telomere length by the human telomeric protein TRF1 , 1997, Nature.
[49] J. Shay,et al. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. , 1996, Cancer research.
[50] E. Blackburn,et al. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines , 1996, Molecular and cellular biology.
[51] T. Metz,et al. Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes , 1995, Cell.
[52] C B Harley,et al. Specific association of human telomerase activity with immortal cells and cancer. , 1994, Science.
[53] E. Blackburn,et al. In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs , 1990, Nature.
[54] Carol W. Greider,et al. Identification of a specific telomere terminal transferase activity in tetrahymena extracts , 1985, Cell.
[55] Y Nishizuka,et al. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. , 1982, The Journal of biological chemistry.