Characterization and pharmacological modulation of noci-responsive deep dorsal horn neurons across diverse rat models of pathological pain.
暂无分享,去创建一个
[1] Xin Lv,et al. Persistent Extracellular Signal-Regulated Kinase Activation by the Histamine H4 Receptor in Spinal Neurons Underlies Chronic Itch. , 2018, The Journal of investigative dermatology.
[2] R. Russo,et al. Antinociceptive effect of two novel transient receptor potential melastatin 8 antagonists in acute and chronic pain models in rat , 2018, British journal of pharmacology.
[3] Jill-Desiree Brederson,et al. Characterization and comparison of rat monosodium iodoacetate and medial meniscal tear models of osteoarthritic pain , 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[4] M. Tsuda. Modulation of Pain and Itch by Spinal Glia , 2017, Neuroscience Bulletin.
[5] L. Rovati,et al. Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis , 2017, Journal of pain research.
[6] A. Gomtsyan,et al. TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. , 2017, Journal of neurophysiology.
[7] R. Thurmond,et al. Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions , 2017, Neuropharmacology.
[8] R. Treede,et al. Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles , 2016, Pain.
[9] B. Cravatt,et al. Robust anti‐nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain , 2016, British journal of pharmacology.
[10] M. Heinricher. Pain Modulation and the Transition from Acute to Chronic Pain. , 2016, Advances in experimental medicine and biology.
[11] H. Stark,et al. Histamine H4 receptor activation alleviates neuropathic pain through differential regulation of ERK, JNK, and P38 MAPK phosphorylation , 2015, Pain.
[12] J. Serra,et al. Effects of a T-type calcium channel blocker, ABT-639, on spontaneous activity in C-nociceptors in patients with painful diabetic neuropathy: a randomized controlled trial , 2015, Pain.
[13] K. Schiene,et al. Electrophysiological characterization of activation state-dependent Cav2 channel antagonist TROX-1 in spinal nerve injured rats , 2015, Neuroscience.
[14] A. Dickenson,et al. Osteoarthritis-dependent changes in antinociceptive action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo electrophysiological study in the rat , 2015, Neuroscience.
[15] L. Li,et al. A selective α2B adrenoceptor agonist (A‐1262543) and duloxetine modulate nociceptive neurones in the medial prefrontal cortex, but not in the spinal cord of neuropathic rats , 2015, European journal of pain.
[16] B. Lumb,et al. Differential contributions of A- and C-nociceptors to primary and secondary inflammatory hypersensitivity in the rat , 2015, Pain.
[17] K. Sałat,et al. Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice , 2015, Journal of Zhejiang University-SCIENCE B.
[18] C. Stucky,et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia , 2015, Naunyn-Schmiedeberg's Archives of Pharmacology.
[19] A. Dickenson,et al. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: A comparison with topical menthol , 2014, PAIN®.
[20] T. Jensen,et al. Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy , 2014, PAIN®.
[21] M. Allegri,et al. Reduction of painful area as new possible therapeutic target in post-herpetic neuropathic pain treated with 5% lidocaine medicated plaster: a case series , 2014, Journal of pain research.
[22] M. Jarvis,et al. A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats. , 2014, Biochemical pharmacology.
[23] F. Porreca,et al. Descending pain modulation and chronification of pain , 2014, Current opinion in supportive and palliative care.
[24] A. Swensen,et al. Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models. , 2014, The journal of pain : official journal of the American Pain Society.
[25] A. Swensen,et al. A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain. , 2014, Journal of neurophysiology.
[26] Gian Domenico Iannetti,et al. Neural coding of nociceptive stimuli—from rat spinal neurones to human perception , 2013, PAIN®.
[27] M. Jarvis,et al. Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats , 2013, PAIN®.
[28] D. Walsh,et al. Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis , 2012, Osteoarthritis and cartilage.
[29] P. Drummond. Sensory-autonomic interactions in health and disease. , 2013, Handbook of clinical neurology.
[30] A. Swensen,et al. A mixed Ca 2 channel blocker , A-1264087 , utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain , 2013 .
[31] J. Rodeau,et al. Interactions between superficial and deep dorsal horn spinal cord neurons in the processing of nociceptive information , 2012, The European journal of neuroscience.
[32] J. Brioni,et al. Antagonism of Supraspinal Histamine H3 Receptors Modulates Spinal Neuronal Activity in Neuropathic Rats , 2012, Journal of Pharmacology and Experimental Therapeutics.
[33] Jill-Desiree Brederson,et al. Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats , 2012, Journal of neuroscience research.
[34] A. Rice,et al. Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain , 2012, European journal of pain.
[35] S. Kishida,et al. Assessment of Gait in a Rat Model of Myofascial Inflammation Using the CatWalk System , 2011, Spine.
[36] R. Gutzmer,et al. Pathogenetic and therapeutic implications of the histamine H4 receptor in inflammatory skin diseases and pruritus. , 2011, Frontiers in bioscience.
[37] M. Rowbotham,et al. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial , 2011, PAIN.
[38] D. Pinho,et al. Does chronic pain alter the normal interaction between cardiovascular and pain regulatory systems? Pain modulation in the hypertensive-monoarthritic rat. , 2011, The journal of pain : official journal of the American Pain Society.
[39] P. Chandran,et al. TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain , 2011, Brain Research.
[40] M. Pitcher,et al. Role of the NKCC1 co-transporter in sensitization of spinal nociceptive neurons , 2010, PAIN®.
[41] A. Todd,et al. Neuronal circuitry for pain processing in the dorsal horn , 2010, Nature Reviews Neuroscience.
[42] A. Vasudevan,et al. Characterization of Fasudil in preclinical models of pain. , 2010, The journal of pain : official journal of the American Pain Society.
[43] R. Baron,et al. Post-herpetic neuralgia: 5% lidocaine medicated plaster, pregabalin, or a combination of both? A randomized, open, clinical effectiveness study , 2010, Current medical research and opinion.
[44] G. Carli,et al. Enriched environment and the recovery from inflammatory pain: Social versus physical aspects and their interaction , 2010, Behavioural Brain Research.
[45] Jill M. Wetter,et al. H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats , 2010, Pharmacology Biochemistry and Behavior.
[46] P. Kym,et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats , 2010, Molecular pain.
[47] Louis P. Vera-Portocarrero,et al. Unmasking the tonic-aversive state in neuropathic pain , 2009, Nature Neuroscience.
[48] M. L. Sotgiu,et al. Cooperative N-methyl-D-aspartate (NMDA) receptor antagonism and mu-opioid receptor agonism mediate the methadone inhibition of the spinal neuron pain-related hyperactivity in a rat model of neuropathic pain. , 2009, Pharmacological research.
[49] Ryan K. Butler,et al. Stress-induced analgesia , 2009, Progress in Neurobiology.
[50] S. McGaraughty,et al. A CB2 receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: Contributions of spinal and peripheral CB2 receptors , 2009, Neuroscience.
[51] T. Takazawa,et al. Actions of propofol on substantia gelatinosa neurones in rat spinal cord revealed by in vitro and in vivo patch‐clamp recordings , 2009, The European journal of neuroscience.
[52] J. Brioni,et al. Localization of histamine H4 receptors in the central nervous system of human and rat , 2009, Brain Research.
[53] K. Chu. CB 2 RECEPTOR AGONIST , A-836339 , MODULATES WIDE YNAMIC RANGE NEURONAL ACTIVITY IN NEUROPATHIC RATS : ONTRIBUTIONS OF SPINAL AND PERIPHERAL CB 2 RECEPTORS a , 2009 .
[54] P. Honore,et al. Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats. , 2008, Journal of neurophysiology.
[55] G. Pitcher,et al. Governing role of primary afferent drive in increased excitation of spinal nociceptive neurons in a model of sciatic neuropathy , 2008, Experimental Neurology.
[56] D. Simone,et al. Changes in response properties of nociceptive dorsal horn neurons in a murine model of cancer pain. , 2008, Sheng li xue bao : [Acta physiologica Sinica].
[57] P. Dougherty,et al. Behavioral and electrophysiological studies in rats with cisplatin-induced chemoneuropathy , 2008, Brain Research.
[58] A. Gomtsyan,et al. (R)-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo , 2008, Journal of Pharmacology and Experimental Therapeutics.
[59] Fei Yang,et al. Behavioral and Electrophysiological Evidence for the Differential Functions of TRPV1 at Early and Late Stages of Chronic Inflammatory Nociception in Rats , 2008, Neurochemical Research.
[60] T. Meert,et al. The impact of bodyweight and body condition on behavioral testing for painful diabetic neuropathy in the streptozotocin rat model , 2008, Neuroscience Letters.
[61] M. Jarvis,et al. A Selective Nav1.8 Sodium Channel Blocker, A-803467 [5-(4-Chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], Attenuates Spinal Neuronal Activity in Neuropathic Rats , 2008, Journal of Pharmacology and Experimental Therapeutics.
[62] J. Antognini,et al. Immobilizing Doses of Halothane, Isoflurane or Propofol, Do Not Preferentially Depress Noxious Heat-Evoked Responses of Rat Lumbar Dorsal Horn Neurons with Ascending Projections , 2008, Anesthesia and analgesia.
[63] Tomio Inoue,et al. NSAID loxoprofen inhibits high threshold or wide dynamic range neuronal responses in the rat at different time-courses. , 2008, Pharmacological reports : PR.
[64] N. Mirza,et al. Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety , 2007, Neuropharmacology.
[65] J. Antognini,et al. Neurons in the Ventral Spinal Cord Are More Depressed by Isoflurane, Halothane, and Propofol Than Are Neurons in the Dorsal Spinal Cord , 2007, Anesthesia and analgesia.
[66] M. Arras,et al. Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability , 2007, BMC veterinary research.
[67] D. Donnelly-roberts,et al. P2X7-related modulation of pathological nociception in rats , 2007, Neuroscience.
[68] Matthew S. Johnson,et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat , 2007, Proceedings of the National Academy of Sciences.
[69] Y. de Koninck,et al. Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain , 2007, Molecular pain.
[70] Louis P. Vera-Portocarrero,et al. Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization , 2006, Neuroscience.
[71] J. Walker,et al. Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain. , 2006, Journal of neurophysiology.
[72] G. Fox,et al. Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A‐841720, a novel non‐competitive mGluR1 receptor antagonist , 2006, British journal of pharmacology.
[73] S. Summerfield,et al. Investigation into the role of P2X3/P2X2/3 receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study , 2006, British journal of pharmacology.
[74] A. Dickenson,et al. Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury , 2006, Experimental Neurology.
[75] M. Jarvis,et al. Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats. , 2006, Journal of neurophysiology.
[76] D. R. Sagar,et al. Inhibitory effects of CB1 and CB2 receptor agonists on responses of DRG neurons and dorsal horn neurons in neuropathic rats , 2005, The European journal of neuroscience.
[77] K. Kanda,et al. Effect of chronic inflammation on dorsal horn nociceptive neurons in aged rats. , 2005, Journal of neurophysiology.
[78] M. Jarvis,et al. Increased WDR spontaneous activity and receptive field size in rats following a neuropathic or inflammatory injury: implications for mechanical sensitivity , 2004, Neuroscience Letters.
[79] V. Chapman,et al. Cannabinoid CB2 receptor activation inhibits mechanically evoked responses of wide dynamic range dorsal horn neurons in naïve rats and in rat models of inflammatory and neuropathic pain , 2004, The European journal of neuroscience.
[80] B. Stacey,et al. Neuropathic pain symptoms relative to overall pain rating. , 2004, The journal of pain : official journal of the American Pain Society.
[81] William D. Willis,et al. Sensory Mechanisms of the Spinal Cord , 1979, Springer US.
[82] A. Dickenson,et al. Alterations in dorsal horn neurones in a rat model of cancer-induced bone pain , 2003, Pain.
[83] E. Burgard,et al. Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. , 2003, Journal of neurophysiology.
[84] R. Richardson,et al. Effects of an odor paired with illness on startle, freezing, and analgesia in rats , 2003, Physiology & Behavior.
[85] S. Hunt,et al. Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways , 2002, Nature Neuroscience.
[86] P. Mantyh,et al. Spinal Neurons that Possess the Substance P Receptor Are Required for the Development of Central Sensitization , 2002, The Journal of Neuroscience.
[87] K. Martin,et al. An Electrophysiological Study Of The Effects Of Propofol On Native Neuronal Ligand‐Gated Ion Channels , 2001, Clinical and experimental pharmacology & physiology.
[88] A. Pertovaara,et al. Pain Behavior and Response Properties of Spinal Dorsal Horn Neurons Following Experimental Diabetic Neuropathy in the Rat: Modulation by Nitecapone, a COMT Inhibitor with Antioxidant Properties , 2001, Experimental Neurology.
[89] Clifford J. Woolf,et al. Neuronal Plasticity and Signal Transduction in Nociceptive Neurons: Implications for the Initiation and Maintenance of Pathological Pain , 2001, Neurobiology of Disease.
[90] Rie Suzuki,et al. Enlargement of the Receptive Field Size to Low Intensity Mechanical Stimulation in the Rat Spinal Nerve Ligation Model of Neuropathy , 2000, Experimental Neurology.
[91] Frank Birklein,et al. Neurological findings in complex regional pain syndromes--analysis of 145 cases. , 2000, Acta neurologica Scandinavica.
[92] E. Carstens,et al. Behavioral manifestations of neuropathic pain and mechanical allodynia, and changes in spinal dorsal horn neurons, following L4–L6 dorsal root constriction in rats , 1999, Pain.
[93] T. Doubell,et al. Peripheral Inflammation Facilitates Aβ Fiber-Mediated Synaptic Input to the Substantia Gelatinosa of the Adult Rat Spinal Cord , 1999, The Journal of Neuroscience.
[94] A. Dickenson,et al. Electrophysiological characterization of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5‐L6 , 1998, The Journal of physiology.
[95] S. McGaraughty,et al. Effects of Noxious Hindpaw Immersion on Evoked and Spontaneous Firing of Contralateral Convergent Dorsal Horn Neurons in Both Intact and Spinalized Rats , 1997, Brain Research Bulletin.
[96] A. Randich,et al. Responses of primary afferents and spinal dorsal horn neurons to thermal and mechanical stimuli before and during zymosan-induced inflammation of the rat hindpaw , 1997, Brain Research.
[97] T. Doubell,et al. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons , 1996, Nature.
[98] M. L. Sotgiu,et al. A study of early ongoing activity in dorsal horn units following sciatic nerve constriction. , 1994, Neuroreport.
[99] A. Brammer,et al. A comparison of propofol with other injectable anaesthetics in a rat model for measuring cardiovascular parameters , 1993, Laboratory animals.
[100] C. Woolf,et al. Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cord , 1986, The Journal of comparative neurology.
[101] M. Bushnell,et al. Wide-dynamic-range dorsal horn neurons participate in the encoding process by which monkeys perceive the intensity of noxious heat stimuli , 1986, Brain Research.
[102] R. Hughes,et al. Peripheral neuropathy. , 1982, The New England journal of medicine.
[103] W. Willis,et al. Sensory Mechanisms of the Spinal Cord , 1979, Springer US.
[104] R. Skinner,et al. Spinal cord potentials produced by ventral cord volleys in the cat. , 1970, Experimental neurology.
[105] E. Perl,et al. Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn. , 1970, Journal of neurophysiology.
[106] P. Wall,et al. Cord cells responding to touch, damage, and temperature of skin. , 1960, Journal of neurophysiology.
[107] P. Wall,et al. Repetitive discharge of neurons. , 1959, Journal of neurophysiology.
[108] I. Tasaki. Properties of myelinated fibers in frog sciatic nerve and in spinal cord as examined with micro-electrodes. , 1952, The Japanese journal of physiology.