Catechol-o-Methyltransferase Genotype and Childhood Trauma May Interact to Impact Schizotypal Personality Traits

[1]  A. Meyer-Lindenberg,et al.  Dopamine and psychosis: Theory, pathomechanisms and intermediate phenotypes , 2010, Neuroscience & Biobehavioral Reviews.

[2]  Peter B. Jones,et al.  Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children. , 2009, The American journal of psychiatry.

[3]  L. Krabbendam,et al.  Subtle gene–environment interactions driving paranoia in daily life , 2009, Genes, brain, and behavior.

[4]  L. Krabbendam,et al.  Evidence that the COMTVal158Met Polymorphism Moderates Subclinical Psychotic and Affective Symptoms in Unaffected First-Degree Relatives of Patients With Schizophrenia , 2008, European Psychiatry.

[5]  A. Serretti,et al.  The genetics of bipolar disorder: genome ‘hot regions,’ genes, new potential candidates and future directions , 2008, Molecular Psychiatry.

[6]  C. Stefanis,et al.  COMT Val158Met moderation of stress-induced psychosis , 2007, Psychological Medicine.

[7]  C. K. Hsiao,et al.  Genetic and Environmental Influences on Schizotypy among Adolescents in Taiwan: A Multivariate Twin/sibling Analysis , 2007, Behavior genetics.

[8]  M. Leboyer,et al.  Schizotypal dimensions: An intermediate phenotype associated with the COMT high activity allele , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[9]  A. Elkin,et al.  The genetics of bipolar affective disorder , 2007, Current opinion in psychiatry.

[10]  K. Shokat,et al.  Human Catechol-O-Methyltransferase Haplotypes Modulate Protein Expression by Altering mRNA Secondary Structure , 2006, Science.

[11]  Dan J Stein,et al.  Warriors Versus Worriers: The Role of COMT Gene Variants , 2006, CNS Spectrums.

[12]  C. Stefanis,et al.  Mixed handedness is associated with the Disorganization dimension of schizotypy in a young male population , 2006, Schizophrenia Research.

[13]  L. Krabbendam,et al.  Impact of psychological trauma on the development of psychotic symptoms: relationship with psychosis proneness , 2006, British Journal of Psychiatry.

[14]  Hidehiro Iida,et al.  The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia. , 2006, Brain : a journal of neurology.

[15]  M. Leboyer,et al.  Schizotypal dimensions: Continuity between schizophrenia and bipolar disorders , 2005, Schizophrenia Research.

[16]  J. Read,et al.  Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications , 2005, Acta psychiatrica Scandinavica.

[17]  Gonçalo R. Abecasis,et al.  PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data , 2005, Bioinform..

[18]  M. Rietschel,et al.  Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study , 2005, Molecular Psychiatry.

[19]  A. Caspi,et al.  Moderation of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis by a Functional Polymorphism in the Catechol-O-Methyltransferase Gene: Longitudinal Evidence of a Gene X Environment Interaction , 2005, Biological Psychiatry.

[20]  C. Duijn,et al.  The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: A meta-analysis , 2005, Biological Psychiatry.

[21]  P. Chinnery,et al.  Correction: no evidence of an association between the T16189C mtDNA variant and late onset dementia (Gibson et al) , 2004, Journal of Medical Genetics.

[22]  J. Savitz,et al.  Genetic variants implicated in personality: A review of the more promising candidates , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[23]  C. Stefanis,et al.  Variation in catechol-o-methyltransferase val158 met genotype associated with schizotypy but not cognition: A population study in 543 young men , 2004, Biological Psychiatry.

[24]  Abraham Weizman,et al.  COMT: A common susceptibility gene in bipolar disorder and schizophrenia , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[25]  L. Jones,et al.  Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire , 2003, Schizophrenia Research.

[26]  R. Murray,et al.  A quantitative genetic analysis of schizotypal personality traits , 2003, Psychological Medicine.

[27]  R. Bentall,et al.  Childhood trauma and hallucinations in bipolar affective disorder: preliminary investigation. , 2003, The British journal of psychiatry : the journal of mental science.

[28]  M. Newcomb,et al.  Development and validation of a brief screening version of the Childhood Trauma Questionnaire. , 2003, Child abuse & neglect.

[29]  J. Beckmann,et al.  A highly significant association between a COMT haplotype and schizophrenia. , 2002, American journal of human genetics.

[30]  Alessandro Rossi,et al.  Schizotypal dimensions in normals and schizophrenic patients: a comparison with other clinical samples , 2002, Schizophrenia Research.

[31]  J. Os,et al.  Evidence that three dimensions of psychosis have a distribution in the general population , 2002, Psychological Medicine.

[32]  D. Rawlings,et al.  Principal components analysis of the Schizotypal Personality Scale (STA) and the Borderline Personality Scale (STB) , 2001 .

[33]  R. Straub,et al.  Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[34]  F. Coolidge,et al.  Heritability of personality disorders in childhood: a preliminary investigation. , 2001, Journal of personality disorders.

[35]  Jim van Os,et al.  Strauss (1969) revisited: a psychosis continuum in the general population? , 2000, Schizophrenia Research.

[36]  G. Abecasis,et al.  Pedigree tests of transmission disequilibrium , 2000, European Journal of Human Genetics.

[37]  J. Knutson,et al.  The veridicality of punitive childhood experiences reported by adolescents and young adults. , 2000, Child abuse & neglect.

[38]  M. Startup.  Schizotypy, dissociative experiences and childhood abuse: relationships among self-report measures. , 1999, The British journal of clinical psychology.

[39]  U. Wolfradt,et al.  Factor structure of schizotypal traits among adolescents , 1998 .

[40]  Donald Hedeker,et al.  The Altman Self-Rating Mania Scale , 1997, Biological Psychiatry.

[41]  H. Berenbaum,et al.  Familial resemblance of schizotypic traits , 1993, Psychological Medicine.

[42]  G. Claridge,et al.  Reliability and validity of a psychotic traits questionnaire (STQ). , 1991, The British journal of clinical psychology.

[43]  J. Os,et al.  An Experimental Study of Catechol-O-Methyltransferase Val158Met Moderation of Δ-9-Tetrahydrocannabinol-Induced Effects on Psychosis and Cognition , 2006, Neuropsychopharmacology.

[44]  M. Preisig,et al.  Monoamine Oxidase A and Tryptophan Hydroxylase Gene Polymorphisms , 2005, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

[45]  H. Berenbaum,et al.  Psychological trauma and schizotypal symptoms. , 2003, Schizophrenia bulletin.

[46]  C. Stefanis,et al.  Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele , 2002, Molecular Psychiatry.

[47]  G. Gessa,et al.  The role of stress in the pathophysiology of the dopaminergic system , 2000, Molecular Psychiatry.

[48]  G. Abecasis,et al.  A general test of association for quantitative traits in nuclear families. , 2000, American journal of human genetics.

[49]  J. Hewitt,et al.  The factor structure of schizotypy in a normal population , 1989 .

[50]  K. Kendler.  Diagnostic approaches to schizotypal personality disorder: a historical perspective. , 1985, Schizophrenia bulletin.

[51]  G. Claridge,et al.  Schizotypy and hemisphere function—I: Theoretical considerations and the measurement of schizotypy , 1984 .