A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation
暂无分享,去创建一个
M. Hentze | M. Beck | T. Bock | G. Neu-Yilik | A. Kulozik | M. Karuppasamy | Karine Huard | C. Schaffitzel | A. Deniaud | F. Garzoni | S. Masiulis | Kathrin Kerschgens | Martin Beck
[1] G. Hong,et al. Nucleic Acids Research , 2015, Nucleic Acids Research.
[2] R. Melero,et al. Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD. , 2014, Structure.
[3] Gabor T. Herman,et al. Computational Methods for Three-Dimensional Microscopy Reconstruction , 2014 .
[4] S. Cusack,et al. Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2 , 2013, Nucleic acids research.
[5] Bo Chen,et al. Quantitative Analysis in Iterative Classification Schemes for Cryo-EM Application , 2014 .
[6] L. Maquat,et al. Organizing principles of mammalian nonsense-mediated mRNA decay. , 2013, Annual review of genetics.
[7] Osamu Onodera,et al. Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity , 2013, Proceedings of the National Academy of Sciences.
[8] O. Mühlemann,et al. Nonsense-mediated mRNA decay - mechanisms of substrate mRNA recognition and degradation in mammalian cells. , 2013, Biochimica et biophysica acta.
[9] N. Pavletich,et al. mTOR kinase structure, mechanism and regulation by the rapamycin-binding domain , 2013, Nature.
[10] A. Yamashita. Role of SMG‐1‐mediated Upf1 phosphorylation in mammalian nonsense‐mediated mRNA decay , 2013, Genes to cells : devoted to molecular & cellular mechanisms.
[11] H. Le Hir,et al. Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains , 2012, Nucleic acids research.
[12] Genetic Characterization of smg-8 Mutants Reveals No Role in C. elegans Nonsense Mediated Decay , 2012, PloS one.
[13] O. Namy,et al. Sense from nonsense: therapies for premature stop codon diseases. , 2012, Trends in molecular medicine.
[14] Allan Jacobson,et al. NMD: a multifaceted response to premature translational termination , 2012, Nature Reviews Molecular Cell Biology.
[15] H. Urlaub,et al. The cryo-EM structure of the UPF–EJC complex shows UPF1 poised toward the RNA 3′ end , 2012, Nature Structural &Molecular Biology.
[16] F. Hirahara,et al. N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD , 2011, Nucleic acids research.
[17] Silvia Domcke,et al. Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. , 2011, Molecular cell.
[18] I. S. Fernández,et al. The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. , 2011, Genes & development.
[19] B. L. Sibanda,et al. Crystal Structure of DNA-PKcs Reveals a Large Open-Ring Cradle Comprised of HEAT Repeats , 2009, Nature.
[20] T. Halazonetis,et al. Emerging common themes in regulation of PIKKs and PI3Ks , 2009, The EMBO journal.
[21] Michael Sattler,et al. Unusual bipartite mode of interaction between the nonsense‐mediated decay factors, UPF1 and UPF2 , 2009, The EMBO journal.
[22] J. Lykke-Andersen,et al. Execution of nonsense-mediated mRNA decay: what defines a substrate? , 2009, Current opinion in cell biology.
[23] H. Hirano,et al. SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. , 2009, Genes & development.
[24] M Radermacher,et al. DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy. , 2009, Journal of structural biology.
[25] O. Mühlemann,et al. The meaning of nonsense. , 2008, Trends in cell biology.
[26] Phoebe L Stewart,et al. Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. , 2008, Structure.
[27] M. Hentze,et al. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways , 2008, The EMBO journal.
[28] José María Carazo,et al. Image processing for electron microscopy single-particle analysis using XMIPP , 2008, Nature Protocols.
[29] F. Bonneau,et al. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity , 2008, Nature Structural &Molecular Biology.
[30] José María Carazo,et al. Modeling experimental image formation for likelihood-based classification of electron microscopy data. , 2007, Structure.
[31] Ernesto Arias-Palomo,et al. Structure of TOR and its complex with KOG1. , 2007, Molecular cell.
[32] D. Cane,et al. The nonsense-mediated decay RNA surveillance pathway. , 2007, Annual review of biochemistry.
[33] T. Richmond,et al. Multiprotein expression strategy for structural biology of eukaryotic complexes. , 2007, Structure.
[34] G. Herman,et al. Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization , 2007, Nature Methods.
[35] J Bernard Heymann,et al. Bsoft: image processing and molecular modeling for electron microscopy. , 2007, Journal of structural biology.
[36] Wen Jiang,et al. EMAN2: an extensible image processing suite for electron microscopy. , 2007, Journal of structural biology.
[37] Weixian Lu,et al. A time- and cost-efficient system for high-level protein production in mammalian cells. , 2006, Acta crystallographica. Section D, Biological crystallography.
[38] G. Dreyfuss,et al. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. , 2006, Genes & development.
[39] Johannes Söding,et al. The HHpred interactive server for protein homology detection and structure prediction , 2005, Nucleic Acids Res..
[40] Laurence H Pearl,et al. Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs). , 2005, Structure.
[41] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[42] M. Hentze,et al. Nonsense-mediated decay approaches the clinic , 2004, Nature Genetics.
[43] K. Anders,et al. Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. , 2003, Molecular cell.
[44] N. Kleckner,et al. The ATRs, ATMs, and TORs Are Giant HEAT Repeat Proteins , 2003, Cell.
[45] O. Hammarsten,et al. DNA-dependent Protein Kinase Catalytic Subunit STRUCTURAL REQUIREMENTS FOR KINASE ACTIVATION BY DNA ENDS , 2002 .
[46] J. Steitz,et al. Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon , 2000, Cell.
[47] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[48] M van Heel,et al. A new generation of the IMAGIC image processing system. , 1996, Journal of structural biology.
[49] S. Peltz,et al. Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation. , 1995, RNA.