Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine.

[1]  A. Cowman,et al.  Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falciparum. , 1994, The Journal of biological chemistry.

[2]  E. Bauminger,et al.  Further evidence for the interaction of the antimalarial drug amodiaquine with ferriprotoporphyrin IX. , 1993, Biochemical pharmacology.

[3]  S. Ward,et al.  Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation. , 1992, Biochemical pharmacology.

[4]  M. Simon,et al.  Sequence‐specific interaction of the Salmonella Hin recombinase in both major and minor grooves of DNA. , 1992, The EMBO journal.

[5]  I. Gluzman,et al.  Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum. , 1992, Biochemical pharmacology.

[6]  I. Gluzman,et al.  Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. , 1987, Science.

[7]  H. Scott,et al.  Antimalarial activity of Mannich bases derived from 4-(7'-bromo-1',5'-naphthyridin-4'-ylamino)phenol and 4-(7'-trifluoromethylquinolin-4'-ylamino)phenol against Plasmodium falciparum in vitro. , 1987, Annals of tropical medicine and parasitology.

[8]  H. Ginsburg,et al.  Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum. , 1986, Biochemical pharmacology.

[9]  P. Schlesinger,et al.  A perspective on antimalarial action: effects of weak bases on Plasmodium falciparum. , 1986, Biochemical pharmacology.

[10]  D. Warhurst,et al.  A study of the uptake of chloroquine in malaria-infected erythrocytes. High and low affinity uptake and the influence of glucose and its analogues. , 1985, Biochemical pharmacology.

[11]  H. Ginsburg,et al.  Susceptibility of human malaria parasites to chloroquine is pH dependent. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[12]  J. Le bras,et al.  Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance , 1985, Antimicrobial Agents and Chemotherapy.

[13]  H. Ginsburg,et al.  Identification of the acidic compartment of Plasmodium falciparum‐infected human erythrocytes as the target of the antimalarial drug chloroquine. , 1984, The EMBO journal.

[14]  J. Jensen,et al.  Lack of cross-resistance to 4-aminoquinolines in chloroquine-resistant Plasmodium falciparum in vitro. , 1983, The Journal of parasitology.

[15]  D. Warhurst,et al.  The quinine-haemin interaction and its relationship to antimalarial activity. , 1981, Biochemical pharmacology.

[16]  A. Chou,et al.  Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites. , 1980, Biochemistry.

[17]  J. Haynes,et al.  Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique , 1979, Antimicrobial Agents and Chemotherapy.

[18]  C. Lambros,et al.  Synchronization of Plasmodium falciparum erythrocytic stages in culture. , 1979, The Journal of parasitology.

[19]  W. Trager,et al.  Plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method. , 1977, The Journal of parasitology.

[20]  C. D. Fitch,et al.  Chloroquine resistance in malaria: variations of substrate-stimulated chloroquine accumulation. , 1975, The Journal of pharmacology and experimental therapeutics.

[21]  P. Tulkens,et al.  Commentary. Lysosomotropic agents. , 1974, Biochemical pharmacology.

[22]  C. D. Fitch,et al.  High-affinity accumulation of chloroquine by mouse erythrocytes infected with Plasmodium berghei. , 1974, Journal of Clinical Investigation.

[23]  C. D. Fitch.  Chloroquine-Resistant Plasmodium falciparum: Difference in the Handling of 14C-Amodiaquin and 14C-Chloroquine , 1973, Antimicrobial Agents and Chemotherapy.

[24]  C. D. Fitch.  Chloroquine resistance in malaria: a deficiency of chloroquine binding. , 1969, Proceedings of the National Academy of Sciences of the United States of America.

[25]  F. Tendick,et al.  Aminoalkylphenols as Antimalarials. II.1 (Heterocyclic-amino)-α-amino-o-cresols. The Synthesis of Camoquin2 , 1948 .

[26]  O. Sodeinde,et al.  Comparison of the relative in vitro activity of chloroquine and amodiaquine against chloroquine-sensitive strains of P. falciparum. , 1987, Annals of tropical medicine and parasitology.

[27]  D. Warhurst.  Antimalarial interaction with ferriprotoporphyrin IX monomer and its relationship to activity of the blood schizontocides. , 1987, Annals of tropical medicine and parasitology.

[28]  J. Jensen,et al.  Activity of quinoline-containing antimalarials against chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. , 1987, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[29]  A. Breckenridge,et al.  High-performance liquid chromatographic analysis of amodiaquine in human plasma. , 1985, Journal of chromatography.

[30]  W. Peters,et al.  Chemotherapy and drug resistance in malaria. , 1970 .

[31]  E. Weibel.  Stereological principles for morphometry in electron microscopic cytology. , 1969, International review of cytology.