Soluble epoxide hydrolase modulates immune responses in activated astrocytes involving regulation of STAT3 activity

[1]  B. Hammock,et al.  Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders , 2019, Progress in Neurobiology.

[2]  R. Koehler,et al.  Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia , 2018, Scientific Reports.

[3]  C. J. Lee,et al.  Reactive astrocytes in Alzheimer’s disease: A double-edged sword , 2018, Neuroscience Research.

[4]  R. González-Reyes,et al.  Involvement of Astrocytes in Alzheimer’s Disease from a Neuroinflammatory and Oxidative Stress Perspective , 2017, Front. Mol. Neurosci..

[5]  S. Shyue,et al.  Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage , 2017, Journal of Neuroinflammation.

[6]  L. Steardo,et al.  Targeting neuroinflammation in Alzheimer’s disease , 2016, Journal of inflammation research.

[7]  O. Garaschuk,et al.  Neuroinflammation in Alzheimer's disease , 2015, The Lancet Neurology.

[8]  C. Brayne,et al.  A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment , 2015, PloS one.

[9]  Yung-Yang Lin,et al.  Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy , 2015, Brain, Behavior, and Immunity.

[10]  M. Sofroniew,et al.  Early Activation of STAT3 Regulates Reactive Astrogliosis Induced by Diverse Forms of Neurotoxicity , 2014, PloS one.

[11]  Y. Ao,et al.  Heterogeneity of reactive astrocytes , 2014, Neuroscience Letters.

[12]  S. Hwang,et al.  Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. , 2013, American journal of physiology. Heart and circulatory physiology.

[13]  D. Miranda-Saavedra,et al.  The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges , 2013, Briefings in functional genomics.

[14]  B. Barres,et al.  Genomic Analysis of Reactive Astrogliosis , 2012, The Journal of Neuroscience.

[15]  G. Ricevuti,et al.  Mitochondrial Alterations, Oxidative Stress and Neuroinflammation in Alzheimer's Disease , 2012, International journal of immunopathology and pharmacology.

[16]  R. Vassar,et al.  The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis , 2011, Journal of Neuroinflammation.

[17]  A. Pozzi,et al.  EET signaling in cancer , 2011, Cancer and Metastasis Reviews.

[18]  Jialin C. Zheng,et al.  HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway , 2011, PloS one.

[19]  Zheng Zachory Wei,et al.  Astrocytes: implications for neuroinflammatory pathogenesis of Alzheimer's disease. , 2011, Current Alzheimer research.

[20]  O. Pascual,et al.  Glia: The many ways to modulate synaptic plasticity , 2010, Neurochemistry International.

[21]  P. Agostinho,et al.  Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease. , 2010, Current pharmaceutical design.

[22]  G. Münch,et al.  Activated astrocytes: a therapeutic target in Alzheimer’s disease? , 2009, Expert review of neurotherapeutics.

[23]  B. Song,et al.  Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS , 2009, The Journal of Neuroscience.

[24]  S. Bilbo,et al.  Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System , 2009, Front. Behav. Neurosci..

[25]  R. D. Rudic,et al.  Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. , 2009, The American journal of pathology.

[26]  R. Jope,et al.  Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain , 2009, Journal of Neuroinflammation.

[27]  J. Iliff,et al.  Soluble Epoxide Hydrolase Gene Deletion Is Protective Against Experimental Cerebral Ischemia , 2008, Stroke.

[28]  D. Grant,et al.  Distribution and Expression of Soluble Epoxide Hydrolase in Human Brain , 2008, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[29]  D. Gutmann,et al.  Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis , 2008, Nature Neuroscience.

[30]  R. Woltjer,et al.  Manipulation of microglial activation as a therapeutic strategy in Alzheimer's disease. , 2007, Current medicinal chemistry.

[31]  J. Rothstein,et al.  Mechanisms of Disease: astrocytes in neurodegenerative disease , 2006, Nature Clinical Practice Neurology.

[32]  M. Sofroniew,et al.  Essential protective roles of reactive astrocytes in traumatic brain injury. , 2006, Brain : a journal of neurology.

[33]  P. Murray The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[34]  S. Paul,et al.  Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides , 2004, Nature Medicine.

[35]  D. Grant,et al.  Distribution of Soluble Epoxide Hydrolase and of Cytochrome P450 2C8, 2C9, and 2J2 in Human Tissues , 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[36]  S. Haeberlein,et al.  Migration and differentiation of neural precursor cells can be directed by microglia , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[37]  T. Wyss-Coray,et al.  Adult mouse astrocytes degrade amyloid-β in vitro and in situ , 2003, Nature Network Boston.

[38]  C. Kawas,et al.  Immune reactive cells in senile plaques and cognitive decline in Alzheimer’s disease , 2003, Neurobiology of Aging.

[39]  F. Oesch,et al.  The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Tony Wyss-Coray,et al.  Inflammation in Neurodegenerative Disease—A Double-Edged Sword , 2002, Neuron.

[41]  D. Miranda-Saavedra,et al.  The IL-10 / STAT 3-mediated anti-inflammatory response : recent developments and future challenges , 2013 .

[42]  Fotios Pasiouras Recent Developments and Future Challenges , 2012 .