Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation

[1]  A. Madabhushi,et al.  Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation , 2021, NPJ breast cancer.

[2]  Ellery Wulczyn,et al.  Deep learning-based survival prediction for multiple cancer types using histopathology images , 2019, PloS one.

[3]  A. Madabhushi,et al.  Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings , 2019, Breast Cancer Research.

[4]  A. Madabhushi,et al.  Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology , 2019, Nature Reviews Clinical Oncology.

[5]  A. Madabhushi,et al.  HistoQC: An Open-Source Quality Control Tool for Digital Pathology Slides. , 2019, JCO clinical cancer informatics.

[6]  The Gene Ontology Consortium,et al.  The Gene Ontology Resource: 20 years and still GOing strong , 2018, Nucleic Acids Res..

[7]  Brendon M. Baker,et al.  Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration , 2018, APL bioengineering.

[8]  A. Madabhushi,et al.  Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer , 2018, Clinical Cancer Research.

[9]  A. Madabhushi,et al.  Nuclear shape and orientation features from H&E images predict survival in early-stage estrogen receptor-positive breast cancers , 2018, Laboratory Investigation.

[10]  Virginia G Kaklamani,et al.  Adjuvant Chemotherapy Guided by a 21‐Gene Expression Assay in Breast Cancer , 2018, The New England journal of medicine.

[11]  A. Madabhushi,et al.  Image-based risk score to predict recurrence of ER+ breast cancer in ECOG-ACRIN Cancer Research Group E2197. , 2018 .

[12]  A. Madabhushi,et al.  Quantitative nuclear histomorphometry predicts oncotype DX risk categories for early stage ER+ breast cancer , 2018, BMC Cancer.

[13]  A. Madabhushi,et al.  Prediction of recurrence in early stage non-small cell lung cancer using computer extracted nuclear features from digital H&E images , 2017, Scientific Reports.

[14]  Gabriel Popescu,et al.  Quantifying collagen fiber orientation in breast cancer using quantitative phase imaging , 2017, Journal of biomedical optics.

[15]  Jon Griffin,et al.  Digital pathology in clinical use: where are we now and what is holding us back? , 2017, Histopathology.

[16]  Lukas Kontenis,et al.  Changes of collagen ultrastructure in breast cancer tissue determined by second-harmonic generation double Stokes-Mueller polarimetric microscopy. , 2016, Biomedical optics express.

[17]  Virginia G Kaklamani,et al.  Prospective Validation of a 21-Gene Expression Assay in Breast Cancer. , 2015, The New England journal of medicine.

[18]  Alex J Walsh,et al.  Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts , 2015, Journal of biomedical optics.

[19]  B. R. Bass,et al.  3D collagen alignment limits protrusions to enhance breast cancer cell persistence. , 2014, Biophysical journal.

[20]  Simon Osindero,et al.  Conditional Generative Adversarial Nets , 2014, ArXiv.

[21]  H. Jaafar,et al.  Pattern of Collagen Fibers and Localization of Matrix Metalloproteinase 2 and 9 during Breast Cancer Invasion , 2014, Tumori.

[22]  V. Seewaldt ECM stiffness paves the way for tumor cells , 2014, Nature Medicine.

[23]  Guanqing Ou,et al.  Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression , 2014, Nature Medicine.

[24]  Kevin W. Eliceiri,et al.  Automated quantification of aligned collagen for human breast carcinoma prognosis , 2014, Journal of pathology informatics.

[25]  Yuming Liu,et al.  Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer , 2014, Journal of biomedical optics.

[26]  George Lee,et al.  Cell Orientation Entropy (COrE): Predicting Biochemical Recurrence from Prostate Cancer Tissue Microarrays , 2013, MICCAI.

[27]  Andrew H. Beck,et al.  Systematic Analysis of Breast Cancer Morphology Uncovers Stromal Features Associated with Survival , 2011, Science Translational Medicine.

[28]  Early Breast Cancer Trialists' Collaborative Group Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials , 2011, The Lancet.

[29]  K. Eliceiri,et al.  Aligned collagen is a prognostic signature for survival in human breast carcinoma. , 2011, The American journal of pathology.

[30]  Mikala Egeblad,et al.  Dynamic interplay between the collagen scaffold and tumor evolution. , 2010, Current opinion in cell biology.

[31]  P. Friedl,et al.  The Journal of Cell Biology , 2002 .

[32]  Mikala Egeblad,et al.  Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling , 2009, Cell.

[33]  Richard O. Hynes,et al.  The Extracellular Matrix: Not Just Pretty Fibrils , 2009, Science.

[34]  Ben S. Wittner,et al.  Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 , 2009, Nature.

[35]  Kevin W Eliceiri,et al.  Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization. , 2008, Biophysical journal.

[36]  C. Rueden,et al.  Bmc Medicine Collagen Density Promotes Mammary Tumor Initiation and Progression , 2022 .

[37]  E Amler,et al.  Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix. , 2007, Physiological research.

[38]  Paolo P. Provenzano,et al.  Collagen reorganization at the tumor-stromal interface facilitates local invasion , 2006, BMC medicine.

[39]  F. Monzon A Multigene Assay to Predict Recurrence of Tamoxifen-Treated, Node-Negative Breast Cancer , 2006 .

[40]  E. Perez,et al.  E2197: Phase III AT (doxorubicin/docetaxel) vs. AC (doxorubicin/cyclophosphamide) in the adjuvant treatment of node positive and high risk node negative breast cancer , 2005 .

[41]  Y Wang,et al.  Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials , 2005, The Lancet.

[42]  Harvey F. Lodish,et al.  MOLECULAR.CELL.BIOLOGY 5TH.ED , 2003 .

[43]  J. Zavadil,et al.  Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. , 2002, Cancer research.

[44]  Yudong D. He,et al.  Gene expression profiling predicts clinical outcome of breast cancer , 2002, Nature.

[45]  M. Shekhar,et al.  Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression. , 2001, Cancer research.

[46]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[47]  D.,et al.  Regression Models and Life-Tables , 2022 .

[48]  M.,et al.  Statistical and Structural Approaches to Texture , 2022 .