Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway

[1]  J. Qi,et al.  Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli , 2019 .

[2]  J. Lian,et al.  Metabolic pathway engineering for high-level production of 5-hydroxytryptophan in Escherichia coli. , 2018, Metabolic engineering.

[3]  A. Zeng,et al.  Synthetic pathways and processes for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli , 2018, Journal of biological engineering.

[4]  A. Zeng,et al.  Protein and pathway engineering for the biosynthesis of 5‐hydroxytryptophan in Escherichia coli , 2017, Engineering in life sciences.

[5]  G. Jung,et al.  Optimum Rebalancing of the 3-Hydroxypropionic Acid Production Pathway from Glycerol in Escherichia coli. , 2016, ACS synthetic biology.

[6]  Sheng Yang,et al.  Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System , 2015, Applied and Environmental Microbiology.

[7]  Qipeng Yuan,et al.  Engineering bacterial phenylalanine 4-hydroxylase for microbial synthesis of human neurotransmitter precursor 5-hydroxytryptophan. , 2014, ACS synthetic biology.

[8]  K. Kino,et al.  Enhanced synthesis of 5-hydroxy-l-tryptophan through tetrahydropterin regeneration , 2013, AMB Express.

[9]  H. Salis,et al.  Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites , 2013, Nucleic acids research.

[10]  C. Collins,et al.  Modular optimization of multi-gene pathways for fatty acids production in E. coli , 2013, Nature Communications.

[11]  Xueli Zhang,et al.  Combinatorial modulation of galP and glk gene expression for improved alternative glucose utilization , 2012, Applied Microbiology and Biotechnology.

[12]  J. Keasling Manufacturing Molecules Through Metabolic Engineering , 2010, Science.

[13]  Ian K. Blaby,et al.  FolX and FolM Are Essential for Tetrahydromonapterin Synthesis in Escherichia coli and Pseudomonas aeruginosa , 2009, Journal of bacteriology.

[14]  H. Christensen,et al.  Expression, Purification and Enzymatic Characterization of the Catalytic Domains of Human Tryptophan Hydroxylase Isoforms , 2009, The protein journal.

[15]  K. Kino,et al.  Enhancement of L-tryptophan 5-hydroxylation activity by structure-based modification of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum. , 2009, Journal of bioscience and bioengineering.

[16]  R. Gainetdinov,et al.  A Regulatory Domain in the N Terminus of Tryptophan Hydroxylase 2 Controls Enzyme Expression* , 2008, Journal of Biological Chemistry.

[17]  P. Harris,et al.  A simple two step procedure for purification of the catalytic domain of chicken tryptophan hydroxylase 1 in a form suitable for crystallization. , 2008, Protein expression and purification.

[18]  J. W. Frost,et al.  Directed evolution of 2-keto-3-deoxy-6-phosphogalactonate aldolase to replace 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase. , 2007, Journal of the American Chemical Society.

[19]  K. Vrana,et al.  Functional Domains of Human Tryptophan Hydroxylase 2 (hTPH2)* , 2006, Journal of Biological Chemistry.

[20]  J. Loftis,et al.  Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan. , 2006, Pharmacology & therapeutics.

[21]  P. Fitzpatrick Mechanism of aromatic amino acid hydroxylation. , 2003, Biochemistry.

[22]  H. Ichinose,et al.  (6R)-5,6,7,8-Tetrahydro-L-Monapterin from Escherichia coli, a Novel Natural Unconjugated Tetrahydropterin , 2002, Biological chemistry.

[23]  T. Birdsall,et al.  5-Hydroxytryptophan: a clinically-effective serotonin precursor. , 1998, Alternative medicine review : a journal of clinical therapeutic.