Enhanced butanol production in Clostridium acetobutylicum ATCC 824 by double overexpression of 6-phosphofructokinase and pyruvate kinase genes

[1]  Tina Lütke-Eversloh,et al.  New options to engineer biofuel microbes: development and application of a high-throughput screening system. , 2013, Metabolic engineering.

[2]  Tina Lütke-Eversloh,et al.  Thiolase engineering for enhanced butanol production in Clostridium acetobutylicum , 2013, Biotechnology and bioengineering.

[3]  Ying Zhang,et al.  Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway. , 2012, Metabolic engineering.

[4]  Y. Jang,et al.  Enhanced Butanol Production Obtained by Reinforcing the Direct Butanol-Forming Route in Clostridium acetobutylicum , 2012, mBio.

[5]  Z. Dragovic,et al.  Over-expression of stress protein-encoding genes helps Clostridium acetobutylicum to rapidly adapt to butanol stress , 2012, Biotechnology Letters.

[6]  H. Bahl,et al.  The redox-sensing protein Rex, a transcriptional regulator of solventogenesis in Clostridium acetobutylicum , 2012, Applied Microbiology and Biotechnology.

[7]  James C. Liao,et al.  ATP drives direct photosynthetic production of 1-butanol in cyanobacteria , 2012, Proceedings of the National Academy of Sciences.

[8]  Bryan S. Biehl,et al.  Insight into the Transmission Biology and Species-Specific Functional Capabilities of Tsetse (Diptera: Glossinidae) Obligate Symbiont Wigglesworthia , 2012, mBio.

[9]  H. Bahl,et al.  Modifying the product pattern of Clostridium acetobutylicum , 2012, Applied Microbiology and Biotechnology.

[10]  H. Bahl,et al.  Metabolic engineering of Clostridium acetobutylicum: recent advances to improve butanol production. , 2011, Current opinion in biotechnology.

[11]  J. Rabinowitz,et al.  Metabolome Remodeling during the Acidogenic-Solventogenic Transition in Clostridium acetobutylicum , 2011, Applied and Environmental Microbiology.

[12]  J. Liao,et al.  Driving Forces Enable High-Titer Anaerobic 1-Butanol Synthesis in Escherichia coli , 2011, Applied and Environmental Microbiology.

[13]  Zugen Chen,et al.  Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield. , 2010, Journal of proteome research.

[14]  E. Papoutsakis,et al.  Aldehyde–alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations , 2009, Biotechnology and bioengineering.

[15]  E. Papoutsakis,et al.  Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. , 2008, Metabolic engineering.

[16]  E. Papoutsakis Engineering solventogenic clostridia. , 2008, Current opinion in biotechnology.

[17]  L. Nielsen,et al.  Fermentative butanol production by clostridia , 2008, Biotechnology and bioengineering.

[18]  P. Dürre Fermentative Butanol Production , 2008, Annals of the New York Academy of Sciences.

[19]  E. Papoutsakis,et al.  Transcriptional Analysis of spo0A Overexpression in Clostridium acetobutylicum and Its Effect on the Cell's Response to Butanol Stress , 2004, Journal of bacteriology.

[20]  E. Papoutsakis,et al.  Comparison between in vivo and in vitro enzyme activities in continuous and batch fermentations of Clostridium acetobutylicum , 1989, Applied Microbiology and Biotechnology.

[21]  E. Papoutsakis,et al.  Increased levels of ATP and NADH are associated with increased solvent production in continuous cultures of Clostridium acetobutylicum , 1989, Applied Microbiology and Biotechnology.

[22]  G. Gottschalk,et al.  The internal pH of Clostridium acetobutylicum and its effect on the shift from acid to solvent formation , 1985, Archives of Microbiology.

[23]  C. Tomas,et al.  Overexpression of groESL in Clostridium acetobutylicum Results in Increased Solvent Production and Tolerance, Prolonged Metabolism, and Changes in the Cell's Transcriptional Program , 2003, Applied and Environmental Microbiology.

[24]  N. Qureshi,et al.  Recent advances in ABE fermentation: hyper-butanol producing Clostridium beijerinckii BA101 , 2001, Journal of Industrial Microbiology and Biotechnology.

[25]  E. Papoutsakis,et al.  Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: need for new phenomenological models for solventogenesis and butanol inhibition? , 2000, Biotechnology and bioengineering.

[26]  E. Papoutsakis,et al.  Metabolic flux analysis elucidates the importance of the acid-formation pathways in regulating solvent production by Clostridium acetobutylicum. , 1999, Metabolic engineering.

[27]  George N. Bennett,et al.  Regulation of the sol Locus Genes for Butanol and Acetone Formation in Clostridium acetobutylicumATCC 824 by a Putative Transcriptional Repressor , 1999, Journal of bacteriology.

[28]  G. Bennett,et al.  Cloning, Sequence, and Expression of the Phosphofructokinase Gene of Clostridium acetobutylicum ATCC 824 in Escherichia coli , 1998, Current Microbiology.

[29]  E. Papoutsakis,et al.  Genetic manipulation of acid formation pathways by gene inactivation in Clostridium acetobutylicum ATCC 824. , 1996, Microbiology.

[30]  E. Papoutsakis,et al.  In vivo methylation in Escherichia coli by the Bacillus subtilis phage phi 3T I methyltransferase to protect plasmids from restriction upon transformation of Clostridium acetobutylicum ATCC 824 , 1993, Applied and environmental microbiology.

[31]  H. Blaschek,et al.  Isolation and characterization of Clostridium acetobutylicum mutants with enhanced amylolytic activity , 1991, Applied and environmental microbiology.

[32]  D. T. Jones,et al.  Acetone-butanol fermentation revisited. , 1986, Microbiological reviews.

[33]  S. Gatenbeck,et al.  Intermediary Metabolism in Clostridium acetobutylicum: Levels of Enzymes Involved in the Formation of Acetate and Butyrate , 1984, Applied and environmental microbiology.

[34]  G. L. Miller Use of Dinitrosalicylic Acid Reagent for Determination of Reducing Sugar , 1959 .