Geometric calibration and correction for a lens-coupled detector in x-ray phase-contrast imaging

Abstract. A lens-coupled x-ray camera with a tilted phosphor collects light emission from the x-ray illuminated (front) side of phosphor. Experimentally, it has been shown to double x-ray photon capture efficiency and triple the spatial resolution along the phosphor tilt direction relative to the same detector at normal phosphor incidence. These characteristics benefit grating-based phase-contrast methods, where linear interference fringes need to be clearly resolved. However, both the shallow incident angle on the phosphor and lens aberrations of the camera cause geometric distortions. When tiling multiple images of limited vertical view into a full-field image, geometric distortion causes blurring due to image misregistration. Here, we report a procedure of geometric correction based on global polynomial transformation of image coordinates. The corrected image is equivalent to one obtained with a single full-field flat panel detector placed at the sample plane. In a separate evaluation scan, the position deviations in the horizontal and vertical directions were reduced from 0.76 and 0.028 mm, respectively, to 0.006 and 0.009 mm, respectively, by the correction procedure, which were below the 0.028-mm pixel size of the imaging system. In a demonstration of a phase-contrast imaging experiment, the correction reduced blurring of small structures.

[1]  J M Boone,et al.  Analysis and correction of imperfections in the image intensifier-TV-digitizer imaging chain. , 1991, Medical physics.

[2]  Marco Stampanoni,et al.  Tilted-grating approach for scanning-mode X-ray phase contrast imaging. , 2014, Optics express.

[3]  L L Fajardo,et al.  Lens distortion in optically coupled digital x-ray imaging. , 2000, Medical physics.

[4]  N. A. Borghese,et al.  Distortion correction for x-ray image intensifiers: local unwarping polynomials and RBF neural networks. , 2002, Medical physics.

[5]  Rebecca Fahrig,et al.  Correction of XRII geometric distortion using a liquid-filled grid and image subtraction. , 2004, Medical physics.

[6]  Dong Gyu Kim,et al.  Distortion correction for digital subtraction angiography imaging: PC based system for radiosurgery planning , 2003, Comput. Methods Programs Biomed..

[7]  A. Panna,et al.  Performance of low-cost X-ray area detectors with consumer digital cameras , 2015 .

[8]  Shiju Yan,et al.  A method based on moving least squares for XRII image distortion correction. , 2007, Medical physics.

[9]  David M Paganin,et al.  Quantitative x-ray phase-contrast imaging using a single grating of comparable pitch to sample feature size. , 2011, Optics Letters.

[10]  N. Pallikarakis,et al.  A novel approach for distortion correction for X-ray image intensifiers. , 2003, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[11]  Angela E. Kedgley,et al.  Image intensifier distortion correction for fluoroscopic RSA: the need for independent accuracy assessment , 2012, Journal of applied clinical medical physics.

[12]  R Fahrig,et al.  Three-dimensional computed tomographic reconstruction using a C-arm mounted XRII: correction of image intensifier distortion. , 1997, Medical physics.

[13]  S Rudin,et al.  Super-global distortion correction for a rotational C-arm x-ray image intensifier. , 1999, Medical physics.

[14]  Angelo Cappello,et al.  A global method based on thin-plate splines for correction of geometric distortion: an application to fluoroscopic images. , 2003, Medical physics.

[15]  Luis F. Gutiérrez,et al.  A practical global distortion correction method for an image intensifier based x-ray fluoroscopy system. , 2008, Medical physics.

[16]  Gerhard Martens,et al.  Slit-scanning differential phase-contrast mammography: first experimental results , 2014, Medical Imaging.

[17]  David A Jaffray,et al.  Accurate technique for complete geometric calibration of cone-beam computed tomography systems. , 2005, Medical physics.

[18]  E. Gronenschild,et al.  Correction for geometric image distortion in the x-ray imaging chain: local technique versus global technique. , 1999, Medical physics.

[19]  Han Wen,et al.  Enhancing Tabletop X-Ray Phase Contrast Imaging with Nano-Fabrication , 2015, Scientific reports.

[20]  A. Pedotti,et al.  Hierarchical radial basis function networks and local polynomial un-warping for X-ray image intensifier distortion correction: A comparison with global techniques , 2003, Medical and Biological Engineering and Computing.

[21]  H. Wen,et al.  A Universal Moiré Effect and Application in X-Ray Phase-Contrast Imaging , 2016, Nature Physics.

[22]  Han Wen,et al.  Spatial Harmonic Imaging of X-ray Scattering—Initial Results , 2008, IEEE Transactions on Medical Imaging.

[23]  E. Gronenschild,et al.  The accuracy and reproducibility of a global method to correct for geometric image distortion in the x-ray imaging chain. , 1997, Medical physics.

[24]  J H Siewerdsen,et al.  High energy x-ray phase contrast CT using glancing-angle grating interferometers. , 2014, Medical physics.