( DEFUSE 2 ) Investigators for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2

for Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 Gregory W. Albers Stephanie Kemp, Ryan McTaggart, Manabu Inoue, Greg Zaharchuk, Roland Bammer and Michael P. Marks, Maarten G. Lansberg, Michael Mlynash, Jean-Marc Olivot, Matus Straka, Ischemic Stroke Effect of Collateral Blood Flow on Patients Undergoing Endovascular Therapy for Acute Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/STROKEAHA.113.004085 2014;45:1035-1039; originally published online February 25, 2014; Stroke. http://stroke.ahajournals.org/content/45/4/1035 World Wide Web at: The online version of this article, along with updated information and services, is located on the

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[6]  Geoffrey A. Donnan,et al.  RAPID Automated Patient Selection for Reperfusion Therapy: A Pooled Analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study , 2011, Stroke.

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[8]  R. Bammer,et al.  Real‐time diffusion‐perfusion mismatch analysis in acute stroke , 2010, Journal of magnetic resonance imaging : JMRI.

[9]  R. Bammer,et al.  Optimal Tmax Threshold for Predicting Penumbral Tissue in Acute Stroke , 2009, Stroke.

[10]  Keith Muir,et al.  Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial , 2008, The Lancet Neurology.

[11]  F Viñuela,et al.  Impact of collateral flow on tissue fate in acute ischaemic stroke , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.

[12]  Scott Hamilton,et al.  Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study , 2006, Annals of neurology.

[13]  Steven Warach,et al.  Trial design and reporting standards for intraarterial cerebral thrombolysis for acute ischemic stroke. , 2003, Journal of vascular and interventional radiology : JVIR.

[14]  R. Higashida,et al.  Trial Design and Reporting Standards for Intra-Arterial Cerebral Thrombolysis for Acute Ischemic Stroke , 2003, Stroke.

[15]  M. Kaste,et al.  Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS) , 1995, JAMA.

[16]  M. Kaste,et al.  The European Cooperative Acute Stroke Study (ECASS) , 1993 .

[17]  J. Broadhead,et al.  WHO consensus statement. , 1990, The British journal of psychiatry : the journal of mental science.

[18]  Joanna M. Wardlaw,et al.  Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke: A Consensus Statement , 2013, Stroke.

[19]  P. Barber,et al.  Failure of Collateral Blood Flow is Associated with Infarct Growth in Ischemic Stroke , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[20]  Manabu Inoue,et al.  MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study , 2012, The Lancet Neurology.

[21]  C. Molina,et al.  Extending the Time Window for Endovascular Procedures According to Collateral Pial Circulation , 2011, Stroke.

[22]  D. Liebeskind,et al.  Collateral Flow Averts Hemorrhagic Transformation After Endovascular Therapy for Acute Ischemic Stroke , 2011, Stroke.

[23]  Geoffrey A. Donnan,et al.  RAPID Automated Patient Selection for Reperfusion Therapy: A Pooled Analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study , 2011, Stroke.

[24]  D. Liebeskind,et al.  Collateral Flow Predicts Response to Endovascular Therapy for Acute Ischemic Stroke , 2011, Stroke.

[25]  R. Bammer,et al.  Real‐time diffusion‐perfusion mismatch analysis in acute stroke , 2010, Journal of magnetic resonance imaging : JMRI.

[26]  R. Bammer,et al.  Optimal Tmax Threshold for Predicting Penumbral Tissue in Acute Stroke , 2009, Stroke.

[27]  Keith Muir,et al.  Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial , 2008, The Lancet Neurology.

[28]  F Viñuela,et al.  Impact of collateral flow on tissue fate in acute ischaemic stroke , 2007, Journal of Neurology, Neurosurgery, and Psychiatry.

[29]  Scott Hamilton,et al.  Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study , 2006, Annals of neurology.

[30]  R. Higashida,et al.  Trial design and reporting standards for intraarterial cerebral thrombolysis for acute ischemic stroke. 2003. , 2003, Journal of vascular and interventional radiology : JVIR.

[31]  M. Kaste,et al.  Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS) , 1995, JAMA.

[32]  J. Broadhead,et al.  WHO consensus statement. , 1990, The British journal of psychiatry : the journal of mental science.