Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

[1]  J. Trojanowski,et al.  More than just two peas in a pod: common amyloidogenic properties of tau and α-synuclein in neurodegenerative diseases , 2004, Trends in Neurosciences.

[2]  J Ovádi,et al.  TPPP/p25 promotes tubulin assemblies and blocks mitotic spindle formation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[3]  J. Kovács,et al.  Brain-specific p25 protein binds to tubulin and microtubules and induces aberrant microtubule assemblies at substoichiometric concentrations. , 2002, Biochemistry.

[4]  K. Arima,et al.  Tubulin Seeds α-Synuclein Fibril Formation* , 2002, The Journal of Biological Chemistry.

[5]  J. Ávila,et al.  P24, a glycogen synthase kinase 3 (GSK 3) inhibitor. , 2002, Biochimica et biophysica acta.

[6]  J. Payton,et al.  Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells. , 2001, Brain research. Molecular brain research.

[7]  Michel Goedert,et al.  Alpha-synuclein and neurodegenerative diseases , 2001, Nature Reviews Neuroscience.

[8]  Patrick R. Hof,et al.  Tau protein isoforms, phosphorylation and role in neurodegenerative disorders 1 1 These authors contributed equally to this work. , 2000, Brain Research Reviews.

[9]  J. Kenney,et al.  Microtubule-associated Protein 1B Is a Component of Cortical Lewy Bodies and Binds α-Synuclein Filaments* , 2000, The Journal of Biological Chemistry.

[10]  S. Hayashi,et al.  NACP/α-synuclein-positive filamentous inclusions in astrocytes and oligodendrocytes of Parkinson’s disease brains , 2000, Acta Neuropathologica.

[11]  J. Culvenor,et al.  α‐Synuclein Immunoisolation of Glial Inclusions from Multiple System Atrophy Brain Tissue Reveals Multiprotein Components , 1999, Journal of neurochemistry.

[12]  Sid Gilman,et al.  Widespread Alterations of α-Synuclein in Multiple System Atrophy , 1999 .

[13]  P. Højrup,et al.  α-Synuclein Binds to Tau and Stimulates the Protein Kinase A-catalyzed Tau Phosphorylation of Serine Residues 262 and 356* , 1999, The Journal of Biological Chemistry.

[14]  E. Rajnavölgyi,et al.  Carrier design: new generation of polycationic branched polypeptides containing OH groups with prolonged blood survival and diminished in vitro cytotoxicity. , 1999, Bioconjugate chemistry.

[15]  S. Sugano,et al.  A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3 , 1999, Journal of Human Genetics.

[16]  R. Kopito,et al.  Aggresomes: A Cellular Response to Misfolded Proteins , 1998, The Journal of cell biology.

[17]  S. W. Davies,et al.  Filamentous nerve cell inclusions in neurodegenerative diseases , 1998, Current Opinion in Neurobiology.

[18]  R. Aebersold,et al.  A brain-specific activator of cyclin-dependent kinase 5 , 1994, Nature.

[19]  P. Lantos,et al.  Cellular pathology of multiple system atrophy: a review. , 1994, Journal of neurology, neurosurgery, and psychiatry.

[20]  K. Imahori,et al.  A Brain‐Specific Protein p25 Is Localized and Associated with Oligodendrocytes, Neuropil, and Fiber‐Like Structures of the CA3 Hippocampal Region in the Rat Brain , 1993, Journal of neurochemistry.

[21]  V. Saudek,et al.  Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions , 1992, Journal of biomolecular NMR.

[22]  K. Imahori,et al.  A novel brain‐specific 25 kDa protein (p25) is phosphorylated by a Ser/Thr‐Pro kinase (TPK II) from tau protein kinase fractions , 1991, FEBS letters.

[23]  J. Lowe,et al.  The latent membrane protein‐1 in Epstein‐Barr virus‐transformed lymphoblastoid cells is found with ubiquitin‐protein conjugates and heat‐shock protein 70 in lysosomes oriented around the microtubule organizing centre , 1991, The Journal of pathology.

[24]  Jørgen Holst Christensen,et al.  Sequence‐specific binding of the N‐terminal three‐finger fragment of Xenopus transcription factor IIIA to the internal control region of a 5S RNA gene , 1991, FEBS letters.

[25]  K. Jellinger,et al.  Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease , 1989, Brain Research.

[26]  Vladimir N Uversky,et al.  What does it mean to be natively unfolded? , 2002, European journal of biochemistry.

[27]  R. Maccioni,et al.  Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies , 2002, Journal of cellular biochemistry.

[28]  T. Kitagawa,et al.  Enzyme coupled immunoassay of insulin using a novel coupling reagent. , 1976, Journal of biochemistry.