Stability of Boolean networks with generalized canalizing rules.

Boolean networks are discrete dynamical systems in which the state (0 or 1) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to model genetic control, the case of canalizing update rules is of particular interest. A canalizing rule is one for which a node state at time t is determined by the state at time t-1 of a single one of its inputs when that inputting node is in its canalizing state. Previous work on the order-disorder transition in Boolean networks considered complex, nonrandom network topology. In the current paper we extend this previous work to account for canalizing behavior.

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