论文信息 - Kinetic-Effect Models and Their Applications

Kinetic-Effect Models and Their Applications

This article focuses on mathematical models that analyze the time course of drug effects in humans. Any such model, whether parametric or nonparametric, is termed a kinetic-effect model (KEM). These models serve to describe (interpolation) and to predict (extrapolation) the effect–time profile. KEMs are applicable to many problems in pharmaceutics, pharmacology, and clinical pharmacology.

Joachim Grevel

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