How to close a gap junction channel. Efficacies and potencies of uncoupling agents.

[1]  A. Noma,et al.  Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea‐pig. , 1987, The Journal of physiology.

[2]  E. Eugenin,et al.  Gap junctional communication coordinates vasopressin-induced glycogenolysis in rat hepatocytes. , 1998, American journal of physiology. Gastrointestinal and liver physiology.

[3]  Christian Giaume,et al.  Control of gap-junctional communication in astrocytic networks , 1996, Trends in Neurosciences.

[4]  Calcium waves between astrocytes from Cx43 knockout mice , 1998 .

[5]  R. Werner,et al.  Mutational analysis of gap junction formation. , 1992, Biophysical journal.

[6]  R. Lerner,et al.  The Sleep-inducing Lipid Oleamide Deconvolutes Gap Junction Communication and Calcium Wave Transmission in Glial Cells , 1997, The Journal of cell biology.

[7]  D. Logothetis,et al.  Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons , 1989, Neuron.

[8]  R. Manalis.  Voltage-dependent effect of curare at the frog neuromuscular junction , 1977, Nature.

[9]  R. Bruzzone,et al.  Expression of a dominant negative inhibitor of intercellular communication in the early Xenopus embryo causes delamination and extrusion of cells. , 1995, Development.

[10]  P. Andrews,et al.  Structural specificity of barbiturates and related drugs. , 1982, Anesthesiology.

[11]  C. Lo,et al.  Genes, gene knockouts, and mutations in the analysis of gap junctions. , 1999, Developmental genetics.

[12]  M Delmar,et al.  PH regulation of connexin43: molecular analysis of the gating particle. , 1996, Biophysical journal.

[13]  G. Fishman,et al.  Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. , 1996, Gene therapy.

[14]  K. Fischbeck,et al.  Connexin32‐null mice develop demyelinating peripheral neuropathy , 1998, Glia.

[15]  R. Dehaan,et al.  Specific motifs in the external loops of connexin proteins can determine gap junction formation between chick heart myocytes. , 1995, The Journal of physiology.

[16]  E. Niggli,et al.  Effects of general anesthetics on current flow across membranes in guinea pig myocytes. , 1989, The American journal of physiology.

[17]  S. Hagiwara,et al.  Voltage—current relations in nerve cell membrane of Onchidium verruculatum , 1959, The Journal of physiology.

[18]  D. Spray,et al.  Gap junctional conductance: comparison of sensitivities to H and Ca ions. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[19]  C. Edwards,et al.  Licorice inhibits corticosteroid 11 beta-dehydrogenase of rat kidney and liver: in vivo and in vitro studies. , 1989, Endocrinology.

[20]  D C Spray,et al.  Single-channel events and gating behavior of the cardiac gap junction channel. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Sutcliffe,et al.  Oleamide‐induced Modulation of 5‐Hydroxytryptamine Receptor‐mediated Signaling a , 1998, Annals of the New York Academy of Sciences.

[22]  M. Rook,et al.  Gap junction channels: distinct voltage-sensitive and -insensitive conductance states. , 1994, Biophysical journal.

[23]  G. Lees,et al.  Modulation of GABAA receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis‐9,10‐octadecenoamide (cOA) , 1998, British journal of pharmacology.

[24]  R. Dermietzel,et al.  Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[25]  K. Krnjević.  Cellular and synaptic actions of general anaesthetics. , 1992, General pharmacology.

[26]  D. Spray,et al.  Changes in the Properties of Gap Junctions during Neuronal Differentiation of Hippocampal Progenitor Cells , 1998, The Journal of Neuroscience.

[27]  E. Harley,et al.  Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid. , 1986, Biochemical and biophysical research communications.

[28]  R. Bruzzone,et al.  DOMINANT INHIBITION OF INTERCELLULAR COMMUNICATION BY TWO CHIMERIC CONNEXINS , 1996, Clinical and experimental pharmacology & physiology.

[29]  R. Bruzzone,et al.  Gap junctions: Getting the message through , 1997, Current Biology.

[30]  R. Weingart,et al.  Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells. , 1995, Journal of molecular and cellular cardiology.

[31]  D. Terrar,et al.  Influence of halothane on electrical coupling in cell pairs isolated from guinea‐pig ventricle , 1988, British journal of pharmacology.

[32]  H. Jongsma,et al.  Selective inhibition of gap junction channel activity by synthetic peptides , 1999, The Journal of physiology.

[33]  D. Spray,et al.  Gap junctions in the brain: where, what type, how many and why? , 1993, Trends in Neurosciences.

[34]  M. Lazdunski,et al.  Inhalational anesthetics activate two-pore-domain background K+ channels , 1999, Nature Neuroscience.

[35]  D. Colquhoun,et al.  The actions of tubocurarine at the frog neuromuscular junction. , 1979, The Journal of physiology.

[36]  S. Mathieu,et al.  Inhibition of gap junction intercellular communications of cultured rat hepatocytes by ethanol: role of ethanol metabolism. , 1996, Journal of hepatology.

[37]  M. Frame,et al.  Propagation of mechanically induced intercellular calcium waves via gap junctions and ATP receptors in rat liver epithelial cells. , 1997, Experimental cell research.

[38]  J. Holtman,et al.  Barbiturates: Their in vivo effects and potential biochemical mechanisms , 1982, Progress in Neurobiology.

[39]  R. Weingart,et al.  Modulation of cardiac gap junctions: the mode of action of arachidonic acid. , 1997, Journal of Molecular and Cellular Cardiology.

[40]  J. Délèze,et al.  The recovery of resting potential and input resistance in sheep heart injured by knife or laser , 1970, The Journal of physiology.

[41]  R. Harris,et al.  Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes. , 1997, European journal of pharmacology.

[42]  A Fort,et al.  Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells , 1999, The Journal of physiology.

[43]  R. Werner,et al.  Attempts to define functional domains of gap junction proteins with synthetic peptides. , 1994, Biophysical journal.

[44]  C. Y. Lee.  Chemistry and pharmacology of polypeptide toxins in snake venoms. , 1972, Annual review of pharmacology.

[45]  C. Peracchia,et al.  Chemical Gating of Heteromeric and Heterotypic Gap Junction Channels , 1998, The Journal of Membrane Biology.

[46]  C. Peracchia,et al.  Connexin domains relevant to the chemical gating of gap junction channels. , 1997, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[47]  J. Lindstrom,et al.  Ion channel modulation as the basis for general anesthesia. , 1998, Toxicology letters.

[48]  C. Naus,et al.  A pre-loading method of evaluating gap junctional communication by fluorescent dye transfer. , 1995, BioTechniques.

[49]  C. Bernard.  LEÇONS SUR LES EFFECTS DES SUBSTANCES TOXIQUES ET MÉDICAMENTEUSES , 1968 .

[50]  J. Davidson,et al.  Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. , 1988, The Journal of pharmacology and experimental therapeutics.

[51]  H. Jongsma,et al.  Heptanol-induced decrease in cardiac gap junctional conductance is mediated by a decrease in the fluidity of membranous cholesterol-rich domains , 1993, The Journal of Membrane Biology.

[52]  R. Lerner.  A hypothesis about the endogenous analogue of general anesthesia. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[53]  D. Spray,et al.  Volatile Anesthetics Block Intercellular Communication Between Neonatal Rat Myocardial Cells , 1989, Circulation research.

[54]  D C Spray,et al.  Equilibrium properties of a voltage-dependent junctional conductance , 1981, The Journal of general physiology.

[55]  E. Albuquerque,et al.  The density of acetylcholine receptors and their sensitivity in the postsynaptic membrane of muscle endplates. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[56]  K. Willecke,et al.  Growth inhibition of oncogene-transformed rat fibroblasts by cocultured normal cells: relevance of metabolic cooperation mediated by gap junctions. , 1991, Cancer research.

[57]  C. Ginter,et al.  Opposite voltage gating polarities of two closely related onnexins , 1994, Nature.

[58]  A. Scholz,et al.  Two types of TTX‐resistant and one TTX‐sensitive Na+ channel in rat dorsal root ganglion neurons and their blockade by halothane , 1998, The European journal of neuroscience.

[59]  Intramolecular interactions mediate pH regulation of connexin43 channels. , 1996, Biophysical journal.

[60]  T. Narahashi,et al.  Saxitoxin and Tetrodotoxin: Comparison of Nerve Blocking Mechanism , 1967, Science.

[61]  T. Griffith,et al.  Peptides Homologous to Extracellular Loop Motifs of Connexin 43 Reversibly Abolish Rhythmic Contractile Activity in Rabbit Arteries , 1997, The Journal of physiology.

[62]  J. Burt,et al.  Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides. , 1994, The American journal of physiology.

[63]  J. Trosko,et al.  Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communication. , 1987, Experimental cell research.

[64]  C. R. Fourtner,et al.  Identification of a proline residue as a transduction element involved in voltage gating of gap junctions , 1993, Nature.

[65]  D C Spray,et al.  Gap junctional conductance is a simple and sensitive function of intracellular pH. , 1981, Science.

[66]  W. R. Lieb,et al.  Molecular and cellular mechanisms of general anaesthesia , 1994, Nature.

[67]  J. Trudell,et al.  Sites of Volatile Anesthetic Action on Kainate (Glutamate Receptor 6) Receptors* , 1998, The Journal of Biological Chemistry.

[68]  R. Doll,et al.  Clinical trial of a new carbenoxolone analogue (BX24), zinc sulphate, and vitamin A in the treatment of gastric ulcer , 1972, Gut.

[69]  David C. Spray,et al.  Structure-activity relations of the cardiac gap junction channel. , 1990 .

[70]  J. Nagy,et al.  Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance , 1999, Neuroscience.

[71]  E. R. Dirksen,et al.  Sequence-specific antibodies to connexins block intercellular calcium signaling through gap junctions. , 1998, Cell calcium.

[72]  M. Salpeter,et al.  Distribution of acetylcholine receptors at frog neuromuscular junctions with a discussion of some physiological implications. , 1978, The Journal of physiology.

[73]  M. Rook,et al.  Mechanism of heptanol-induced uncoupling of cardiac gap junctions: a perforated patch-clamp study. , 1992, The American journal of physiology.

[74]  E. Eger,et al.  Anesthetics produce subunit-selective actions on glutamate receptors. , 1996, The Journal of pharmacology and experimental therapeutics.

[75]  T. I. Chao,et al.  Autocellular coupling by gap junctions in cultured astrocytes: A new view on cellular autoregulation during process formation , 1998, Glia.

[76]  D C Spray,et al.  Gap junctional conductance and permeability are linearly related. , 1986, Science.

[77]  K. Patel,et al.  Roles for alpha 1 connexin in morphogenesis of chick embryos revealed using a novel antisense approach. , 1999, Developmental genetics.

[78]  K. Jungermann,et al.  Signal propagation via gap junctions, a key step in the regulation of liver metabolism by the sympathetic hepatic nerves , 1992, FEBS letters.

[79]  R. Lerner,et al.  Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[80]  K. Willecke,et al.  Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cells. , 1995, Biophysical journal.

[81]  M. Durieux,et al.  Influence of volatile anesthetics on thromboxane A2 signaling. , 1998, Anesthesiology.

[82]  D. Spray,et al.  Physiology and pharmacology of gap junctions. , 1985, Annual review of physiology.

[83]  T. Narahashi,et al.  Stabilization and rectification of muscle fiber membrane by tetrodotoxin. , 1960, The American journal of physiology.

[84]  C. Lo,et al.  Expression of a connexin 43/beta-galactosidase fusion protein inhibits gap junctional communication in NIH3T3 cells , 1995, The Journal of cell biology.

[85]  D. Paul,et al.  Genetic diseases and gene knockouts reveal diverse connexin functions. , 1999, Annual review of physiology.

[86]  B. Walker,et al.  Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess. , 1994, Endocrinology and metabolism clinics of North America.

[87]  R. Dermietzel,et al.  Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytes , 1998, Glia.

[88]  T. Griffith,et al.  Central role of heterocellular gap junctional communication in endothelium‐dependent relaxations of rabbit arteries , 1998, The Journal of physiology.

[89]  D. Spray,et al.  Voltage dependence of junctional conductance in early amphibian embryos. , 1979, Science.

[90]  J. Doeller,et al.  Gap junctional conductance between pairs of ventricular myocytes is modulated synergistically by H+ and Ca++ , 1990, The Journal of general physiology.

[91]  P. D'andrea,et al.  Gap junctions mediate intercellular calcium signalling in cultured articular chondrocytes. , 1996, Cell calcium.