Fluoridated HAp:Ln3+ (Ln = Eu or Tb) nanoparticles for cell-imaging.

Water-dispersible hydrophilic fluoridated HAp:Ln(3+) (Ln = Eu or Tb) nanoparticles were prepared via hydrophobic/hydrophilic transformation with surfactants (Pluronic F127). The HAp:Ln(3+) (Ln = Eu or Tb) nanoparticles with unique luminescent properties and excellent biocompatibility are promising for cell imaging applications.

[1]  Jun Lin,et al.  Bioactive, luminescent and mesoporous europium-doped hydroxyapatite as a drug carrier. , 2008, Biomaterials.

[2]  Lei Tao,et al.  PolyPEGylated nanodiamond for intracellular delivery of a chemotherapeutic drug , 2012 .

[3]  N. Margiotta,et al.  Nanocrystalline carbonate-apatites: role of Ca/P ratio on the upload and release of anticancer platinum bisphosphonates. , 2012, Nanoscale.

[4]  Delyan R. Hristov,et al.  Stabilising fluorescent silica nanoparticles against dissolution effects for biological studies. , 2012, Chemical communications.

[5]  Rui L Reis,et al.  Bone tissue engineering: state of the art and future trends. , 2004, Macromolecular bioscience.

[6]  Chunhua Yan,et al.  Colloidal synthesis and blue based multicolor upconversion emissions of size and composition controlled monodisperse hexagonal NaYF4:Yb,Tm nanocrystals. , 2010, Nanoscale.

[7]  Ying-Jie Zhu,et al.  Multifunctional Eu3+/Gd3+ dual-doped calcium phosphate vesicle-like nanospheres for sustained drug release and imaging. , 2012, Biomaterials.

[8]  Xun Wang,et al.  Luminescent, colloidal, F-substituted, hydroxyapatite nanocrystals. , 2011, Chemistry.

[9]  Shiqi Peng,et al.  The intracellular controlled release from bioresponsive mesoporous silica with folate as both targeting and capping agent. , 2012, Nanoscale.

[10]  Xurong Xu,et al.  Surface Modification of Hydroxyapatite Nanocrystallite by a Small Amount of Terbium Provides a Biocompatible Fluorescent Probe , 2008 .

[11]  Ying-Jie Zhu,et al.  Porous nanocomposites of PEG-PLA/calcium phosphate: room-temperature synthesis and its application in drug delivery. , 2010, Dalton transactions.

[12]  R. Yan,et al.  Down/Up Conversion in Ln3+‐Doped YF3 Nanocrystals , 2005 .

[13]  Michel Orrit,et al.  Photobleaching of Rhodamine 6G in Poly(vinyl alcohol) at the Ensemble and Single-Molecule Levels , 2004 .

[14]  Caroline M Curtin,et al.  Innovative Collagen Nano‐Hydroxyapatite Scaffolds Offer a Highly Efficient Non‐Viral Gene Delivery Platform for Stem Cell‐Mediated Bone Formation , 2012, Advanced materials.

[15]  Vishal Saxena,et al.  Enhanced photo-stability, thermal-stability and aqueous-stability of indocyanine green in polymeric nanoparticulate systems. , 2004, Journal of photochemistry and photobiology. B, Biology.

[16]  Clifford R. Pollock,et al.  Synthesis and Fluorescence of Neodymium-Doped Barium Fluoride Nanoparticles , 2000 .

[17]  Xun Wang,et al.  Liquid–Solid–Solution Synthesis of Biomedical Hydroxyapatite Nanorods , 2006 .

[18]  Jeeseong Hwang,et al.  High-sensitivity bacterial detection using biotin-tagged phage and quantum-dot nanocomplexes. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Bin Chen,et al.  Biocompatible Fluorescent Hydroxyapatite: Synthesis and Live Cell Imaging Applications , 2011 .

[20]  Jin Wu,et al.  The photoluminescence, drug delivery and imaging properties of multifunctional Eu3+/Gd3+ dual-doped hydroxyapatite nanorods. , 2011, Biomaterials.

[21]  G. Jiang,et al.  Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling. , 2012, Nanoscale.

[22]  Chunhai Fan,et al.  The cytotoxicity of cadmium-based quantum dots. , 2012, Biomaterials.

[23]  J. Chane-Ching,et al.  Colloidal and monocrystalline Ln3+ doped apatite calcium phosphate as biocompatible fluorescent probes. , 2006, Chemical communications.

[24]  Lei Tao,et al.  A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond , 2012 .

[25]  Hicham A. Chibli,et al.  Cytotoxicity of InP/ZnS quantum dots related to reactive oxygen species generation. , 2011, Nanoscale.

[26]  M. Epple,et al.  Lanthanide-doped calcium phosphate nanoparticles with high internal crystallinity and with a shell of DNA as fluorescent probes in cell experiments , 2007 .

[27]  Lei Tao,et al.  Cellular responses of aniline oligomers: a preliminary study , 2012 .

[28]  Xun Wang,et al.  Monodisperse F-substituted hydroxyapatite single-crystal nanotubes with amphiphilic surface properties. , 2009, Inorganic chemistry.

[29]  Jiang Chang,et al.  Facile synthesis of hydroxyapatite nanoparticles, nanowires and hollow nano-structured microspheres using similar structured hard-precursors. , 2011, Nanoscale.

[30]  Jun Lin,et al.  Solvothermal synthesis and characterization of Ln (Eu3+, Tb3+) doped hydroxyapatite. , 2008, Journal of colloid and interface science.

[31]  Chunhua Yan,et al.  Fluorescent-magnetic nanocrystals: synthesis and property of YP(x)V(1-x)O4:Eu@GdPO4 core/shell structure. , 2011, Nanoscale.

[32]  S. Bhatia,et al.  Probing the Cytotoxicity Of Semiconductor Quantum Dots. , 2004, Nano letters.

[33]  Qing Peng,et al.  A general strategy for nanocrystal synthesis , 2005, Nature.

[34]  Juan L. Vivero-Escoto,et al.  Mesoporous silica nanoparticles for reducing hemolytic activity towards mammalian red blood cells. , 2009, Small.

[35]  Jun Lin,et al.  Size and shape controllable synthesis and luminescent properties of BaGdF5:Ce3+/Ln3+ (Ln = Sm, Dy, Eu, Tb) nano/submicrocrystals by a facile hydrothermal process. , 2011, Nanoscale.

[36]  J. W. Stouwdam,et al.  Near-infrared Emission of Redispersible Er3+, Nd3+, and Ho3+ Doped LaF3 Nanoparticles , 2002 .

[37]  Laetitia Gonzalez,et al.  Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. , 2009, Small.

[38]  Samuel I Stupp,et al.  Biomimetic systems for hydroxyapatite mineralization inspired by bone and enamel. , 2008, Chemical reviews.

[39]  Y. Huang,et al.  Micro-/nano- sized hydroxyapatite directs differentiation of rat bone marrow derived mesenchymal stem cells towards an osteoblast lineage. , 2012, Nanoscale.

[40]  Shaohua Huang,et al.  Controlled synthesis of luminescent F-substituted strontium hydroxyapatite with hierarchical structures for drug delivery , 2012 .

[41]  Y. Mély,et al.  Identification of a thermally activated process in the Cy3 photobleaching mechanism. , 2012, Physical chemistry chemical physics : PCCP.

[42]  Lei Tao,et al.  Biocompatible polydopamine fluorescent organic nanoparticles: facile preparation and cell imaging. , 2012, Nanoscale.

[43]  Jun Lin,et al.  Facile synthesis of an up-conversion luminescent and mesoporous Gd2O3 : Er3+@nSiO2@mSiO2 nanocomposite as a drug carrier. , 2011, Nanoscale.

[44]  Ron C. Hardman.  A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors , 2005, Environmental health perspectives.