Water‐fat imaging with direct phase encoding

A new method is Introduced for water‐fat imaging. With three acquisitions, a general direct phase encoding (DPE) of the chemical shift information is achieved. Pixels containing both water and fat are solved directly. Pixels with only a single component are resolved with local and global orientation filters, which use phase information from neighboring pixels. The fact that a single component is more likely to be water than fat in living tissues is also useful. A second pass solution yields water and fat images with superior signal‐to‐noise ratio. Unlike other methods, DPE does not rely on the error‐prone phase unwrapping; also, it easily handles disconnected tissues. Because the magnetization vectors of water and fat are sampled not only at parallel or antiparallel, they can be not only separated but also identified respectively, which is desirable for routine clinical work. DPE has been implemented on several imagers at various field strengths and has been demonstrated in a large number of clinical cases to be useful and robust in various parts of the body.

[1]  S. F. Quinn,et al.  Double‐echo three‐point‐dixon method for fat suppression MRI , 1995, Magnetic resonance in medicine.

[2]  G H Glover,et al.  Three‐point dixon technique for true water/fat decomposition with B0 inhomogeneity correction , 1991, Magnetic resonance in medicine.

[3]  W. C. Dickinson Dependence of the F$sup 19$ Nuclear Resonance Position on Chemical Compound , 1950 .

[4]  P M Joseph,et al.  A Spin Echo Chemical Shift MR Imaging Technique , 1985, Journal of computer assisted tomography.

[5]  D. M. Fleming,et al.  Hematologic bone marrow disorders: quantitative chemical shift MR imaging. , 1988, Radiology.

[6]  D. Mitchell,et al.  Liver and pancreas: improved spin-echo T1 contrast by shorter echo time and fat suppression at 1.5 T. , 1991, Radiology.

[7]  D. Mitchell,et al.  Focal manifestations of diffuse liver disease at MR imaging. , 1992, Radiology.

[8]  J. Singer,et al.  MR imaging of adrenal masses: value of chemical-shift imaging for distinguishing adenomas from other tumors. , 1995, AJR. American journal of roentgenology.

[9]  T. R. Judge,et al.  A review of phase unwrapping techniques in fringe analysis , 1994 .

[10]  J Szumowski,et al.  Two‐point Dixon technique for water‐fat signal decomposition with B0 inhomogeneity correction , 1997, Magnetic resonance in medicine.

[11]  R M Henkelman,et al.  Motion artifact reduction with three‐point ghost phase cancellation , 1991, Journal of magnetic resonance imaging : JMRI.

[12]  W. G. Proctor,et al.  The Dependence of a Nuclear Magnetic Resonance Frequency upon Chemical Compound , 1950 .

[13]  Jean A. Tkach,et al.  Separation of fat and water in fast spin‐echo MR imaging with the three‐point dixon technique , 1995, Journal of magnetic resonance imaging : JMRI.

[14]  G. Glover Multipoint dixon technique for water and fat proton and susceptibility imaging , 1991, Journal of magnetic resonance imaging : JMRI.

[15]  W. Perman,et al.  Spatially resolved high resolution spectroscopy by “four-dimensional” NMR , 1983 .

[16]  D. Twieg,et al.  A general treatment of NMR imaging with chemical shifts and motion , 1987, Magnetic resonance in medicine.

[17]  Orhan Nalcioglu,et al.  Spectroscopic imaging by quadrature modulated echo time shifting , 1986 .

[18]  R M Henkelman,et al.  K‐space description for MR imaging of dynamic objects , 1993, Magnetic resonance in medicine.

[19]  B. Rosen,et al.  Nuclear magnetic resonance: in vivo proton chemical shift imaging. Work in progress. , 1983, Radiology.

[20]  K. Uğurbil,et al.  NMR chemical shift imaging in three dimensions. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J Szumowski,et al.  Phase unwrapping in the three-point Dixon method for fat suppression MR imaging. , 1994, Radiology.

[22]  D. Mitchell,et al.  Benign adrenocortical masses: diagnosis with chemical shift MR imaging. , 1992, Radiology.

[23]  R. Sepponen,et al.  A Method for Chemical Shift Imaging: Demonstration of Bone Marrow Involvement with Proton Chemical Shift Imaging , 1984, Journal of computer assisted tomography.

[24]  P Schmalbrock,et al.  Multisection fat-water imaging with chemical shift selective presaturation. , 1987, Radiology.

[25]  D W Kormos,et al.  Separation of true fat and water images by correcting magnetic field inhomogeneity in situ. , 1986, Radiology.

[26]  W E Smith,et al.  Flow compensation in MRI using a phase‐corrected real reconstruction , 1993, Magnetic resonance in medicine.

[27]  L. Hall,et al.  True water and fat MR imaging with use of multiple-echo acquisition. , 1989, Radiology.

[28]  R D Tien,et al.  Fat-suppression MR imaging in neuroradiology: techniques and clinical application. , 1992, AJR. American journal of roentgenology.

[29]  G H Glover,et al.  An extended two‐point dixon algorithm for calculating separate water, fat, and B0 images , 1997, Magnetic resonance in medicine.

[30]  W. T. Dixon Simple proton spectroscopic imaging. , 1984, Radiology.

[31]  R M Henkelman,et al.  Two‐point interference method for suppression of ghost artifacts due to motion , 1993, Journal of magnetic resonance imaging : JMRI.

[32]  David P. Towers,et al.  Automatic interferogram analysis techniques applied to quasi-heterodyne holography and ESPI , 1991 .

[33]  C. Ahn,et al.  A New Phase Correction Method in NMR Imaging Based on Autocorrelation and Histogram Analysis , 1987, IEEE Transactions on Medical Imaging.

[34]  D B Plewes,et al.  Changes in fibroglandular volume and water content of breast tissue during the menstrual cycle observed by MR imaging at 1.5 t , 1995, Journal of magnetic resonance imaging : JMRI.

[35]  J. Felmlee,et al.  Proton MR chemical shift imaging using double and triple phase contrast acquisition methods. , 1989, Journal of computer assisted tomography.

[36]  D. Sebok,et al.  Single-acquisition chemical-shift imaging of a binary system with use of stimulated echoes. , 1988, Radiology.