The acute effect of different NAD+ precursors included in the combined metabolic activators.
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J. Borén | M. Uhlén | A. Mardinoğlu | H. Turkez | Gurkan Ozturk | Xiangyu Li | H. Doğanay | Hong Yang | Cheng Zhang | Jens Nielsen | Han Jin
[1] D. Eidelberg,et al. The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. , 2022, Cell metabolism.
[2] N. Sabri,et al. Nicotinamide supplementation in diabetic nonalcoholic fatty liver disease patients: randomized controlled trial , 2022, Therapeutic advances in chronic disease.
[3] J. Nielsen,et al. Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients , 2021, Molecular systems biology.
[4] J. Błasiak,et al. Kynurenine Pathway of Tryptophan Metabolism in Migraine and Functional Gastrointestinal Disorders , 2021, International journal of molecular sciences.
[5] S. Harrison,et al. Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease , 2021, The American journal of gastroenterology.
[6] Danica Chen,et al. The therapeutic promises of NAD+ boosters. , 2021, Cell metabolism.
[7] A. Mouzaki,et al. N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study , 2021, Infectious diseases.
[8] J. Nielsen,et al. Combined Metabolic Activators Accelerates Recovery in Mild‐to‐Moderate COVID‐19 , 2021, Advanced science.
[9] J. Xia,et al. MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights , 2021, Nucleic Acids Res..
[10] A. Hevener,et al. ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity , 2021, Science Translational Medicine.
[11] E. Chini,et al. Evolving concepts in NAD+ metabolism. , 2021, Cell metabolism.
[12] S. Klein,et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women , 2021, Science.
[13] N. Seidah,et al. L-Carnitine Tartrate Downregulates the ACE2 Receptor and Limits SARS-CoV-2 Infection , 2021, Nutrients.
[14] S. Amini,et al. Application of methylene blue -vitamin C –N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial , 2020, European Journal of Pharmacology.
[15] M. Mattson,et al. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing , 2020, Nature Reviews Drug Discovery.
[16] A. Perl,et al. Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine , 2020, Clinical Immunology.
[17] G. Kroemer,et al. Nutritional Aspects of Spermidine. , 2020, Annual review of nutrition.
[18] Mark S. Schmidt,et al. Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy. , 2020, Cell metabolism.
[19] J. Auwerx,et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans , 2020, The American journal of clinical nutrition.
[20] J. Nielsen,et al. The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non‐alcoholic fatty liver disease , 2020, Molecular systems biology.
[21] D. Sinclair,et al. Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers , 2020, Cells.
[22] Ying Wang,et al. COVID-19 infection: the perspectives on immune responses , 2020, Cell Death & Differentiation.
[23] P. Wilmes,et al. Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function. , 2020, Cell metabolism.
[24] D. Sabatini,et al. Dietary modifications for enhanced cancer therapy , 2020, Nature.
[25] Michel E. Vandenberghe,et al. Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease , 2019, SSRN Electronic Journal.
[26] David A. Knowles,et al. Molecular Choreography of Acute Exercise , 2020, Cell.
[27] J. Auwerx,et al. NAD+ homeostasis in health and disease , 2020, Nature Metabolism.
[28] P. Chanson,et al. Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case–control study , 2019, Psychiatry and clinical neurosciences.
[29] E. Rhee,et al. NAD+ homeostasis in renal health and disease , 2019, Nature Reviews Nephrology.
[30] Mark S. Schmidt,et al. Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures , 2019, Cell reports.
[31] Markus M. Rinschen,et al. Identification of bioactive metabolites using activity metabolomics , 2019, Nature Reviews Molecular Cell Biology.
[32] D. Butterfield,et al. Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease , 2019, Nature Reviews Neuroscience.
[33] H. A. Abd El Latif,et al. Improvement of insulin resistance via increase of GLUT4 and PPARγ in metabolic syndrome‐induced rats treated with omega‐3 fatty acid or l‐carnitine , 2018, Journal of biochemical and molecular toxicology.
[34] Mark S. Schmidt,et al. A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. , 2018, The American journal of clinical nutrition.
[35] A. Whitworth,et al. The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease. , 2018, Cell reports.
[36] W. Le,et al. Potential biomarkers of Parkinson's disease revealed by plasma metabolic profiling. , 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[37] M. McQueen,et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults , 2018, Nature Communications.
[38] D. Sinclair,et al. Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence. , 2018, Cell metabolism.
[39] M. Mattson,et al. NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency , 2018, Proceedings of the National Academy of Sciences.
[40] Guido Kroemer,et al. Spermidine in health and disease , 2018, Science.
[41] M. Mattson,et al. Intermittent metabolic switching, neuroplasticity and brain health , 2018, Nature Reviews Neuroscience.
[42] Hong Wang,et al. Protein Expression Landscape of Mouse Embryos during Pre-implantation Development. , 2017, Cell reports.
[43] B. Ogretmen,et al. Sphingolipid metabolism in cancer signalling and therapy , 2017, Nature Reviews Cancer.
[44] Jens Nielsen,et al. Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD , 2017, Molecular systems biology.
[45] P. Lewitt,et al. Metabolomic biomarkers as strong correlates of Parkinson disease progression , 2017, Neurology.
[46] K. Hirata,et al. 2-Aminobutyric acid modulates glutathione homeostasis in the myocardium , 2016, Scientific Reports.
[47] Mark S. Schmidt,et al. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans , 2016, Nature Communications.
[48] B. Gregory,et al. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. , 2016, Cell metabolism.
[49] G. Hatch,et al. Mitochondrial phospholipids: role in mitochondrial function , 2016, Journal of Bioenergetics and Biomembranes.
[50] B. Weinberger,et al. Inherited disorders of bilirubin clearance , 2016, Pediatric Research.
[51] I. Poon,et al. The phospholipid code: a key component of dying cell recognition, tumor progression and host–microbe interactions , 2015, Cell Death and Differentiation.
[52] Jens Nielsen,et al. New paradigms for metabolic modeling of human cells. , 2015, Current opinion in biotechnology.
[53] S. Claypool,et al. Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes , 2015, Front. Genet..
[54] J. Stuart,et al. Unbalanced Activation of Glutathione Metabolic Pathways Suggests Potential Involvement in Plant Defense against the Gall Midge Mayetiola destructor in Wheat , 2015, Scientific Reports.
[55] Malika Charrad,et al. NbClust: An R Package for Determining the Relevant Number of Clusters in a Data Set , 2014 .
[56] Sarah Spiegel,et al. Sphingolipid metabolites in inflammatory disease , 2014, Nature.
[57] M. Uhlén,et al. Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease , 2014, Nature Communications.
[58] Jens Nielsen,et al. Genome‐scale modeling of human metabolism – a systems biology approach , 2013, Biotechnology journal.
[59] S. Imai,et al. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. , 2011, Cell metabolism.
[60] David S. Wishart,et al. MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data , 2010, Nucleic Acids Res..
[61] Ulrich Klotz,et al. Pharmacokinetics and drug metabolism in the elderly , 2009, Drug metabolism reviews.
[62] R. Pamplona. Membrane phospholipids, lipoxidative damage and molecular integrity: a causal role in aging and longevity. , 2008, Biochimica et biophysica acta.
[63] R. Weinshilboum,et al. Metabolomics: a global biochemical approach to drug response and disease. , 2008, Annual review of pharmacology and toxicology.
[64] Lokesh Kumar,et al. Mfuzz: A software package for soft clustering of microarray data , 2007, Bioinformation.
[65] H. Bays,et al. Safety considerations with niacin therapy. , 2007, The American journal of cardiology.
[66] Z. Benyó,et al. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. , 2005, The Journal of clinical investigation.
[67] A. Tchernof,et al. Lipid metabolism in the elderly , 2000, European journal of clinical nutrition.
[68] Dean P. Jones,et al. Redox state of glutathione in human plasma. , 2000, Free radical biology & medicine.
[69] Jacob Cohen,et al. A power primer. , 1992, Psychological bulletin.
[70] H. Jörnvall,et al. Metabolism of glutathione and a glutathione conjugate by isolated kidney cells. , 1979, The Journal of biological chemistry.
[71] T. Becker,et al. Effects of lipids on mitochondrial functions. , 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.
[72] Yuan Luo,et al. A Phase II Randomized Clinical Trial of a Nutritional Formulation for Cognition and Mood in Alzheimer's Disease. , 2015, Journal of Alzheimer's disease : JAD.
[73] S. Carrasco,et al. Diacylglycerol, when simplicity becomes complex. , 2007, Trends in biochemical sciences.
[74] J. Slotte,et al. Cholesterol interactions with phospholipids in membranes. , 2002, Progress in lipid research.