Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway
暂无分享,去创建一个
I. Shimomura | M. Otsuki | Hironori Kobayashi | A. Fukuhara | E. Hashimoto | Y. Okuno | Sachiko Kobayashi
[1] R. Cox,et al. Exploring the Lean Phenotype of Glutathione-Depleted Mice: Thiol, Amino Acid and Fatty Acid Profiles , 2016, PloS one.
[2] M. Ciriolo,et al. Glutathione Decrement Drives Thermogenic Program In Adipose Cells , 2015, Scientific Reports.
[3] K. Clément,et al. Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity , 2015, Nature Medicine.
[4] K. Cho,et al. Flow cytometry analyses of adipose tissue macrophages. , 2014, Methods in enzymology.
[5] Y. Inagaki,et al. Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis , 2014, Nature Communications.
[6] Fajun Yang,et al. Regulation of Lipogenic Gene Expression by Lysine-specific Histone Demethylase-1 (LSD1)* , 2014, The Journal of Biological Chemistry.
[7] Jing Liang,et al. Destabilizing LSD1 by Jade-2 promotes neurogenesis: an antibraking system in neural development. , 2014, Molecular cell.
[8] Caroline Tao,et al. Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling. , 2014, Cell metabolism.
[9] Chi Wang,et al. The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells. , 2013, Cell reports.
[10] A. Salmon,et al. Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase. , 2013, Biochemical and biophysical research communications.
[11] A. Saito,et al. Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue , 2012, Scientific Reports.
[12] D. McClain,et al. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity , 2012, Nature Medicine.
[13] I. Shimomura,et al. Expression of activating transcription factor 2 in inflammatory macrophages in obese adipose tissue , 2012, Obesity.
[14] M. Blüher,et al. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism , 2012, Nature.
[15] T. Funahashi,et al. Contribution of glucocorticoid-mineralocorticoid receptor pathway on the obesity-related adipocyte dysfunction. , 2012, Biochemical and biophysical research communications.
[16] D. Nebert,et al. Lipid metabolism and body composition in Gclm(-/-) mice. , 2011, Toxicology and applied pharmacology.
[17] T. Funahashi,et al. Cross-sectional and longitudinal study of association between circulating thiobarbituric acid-reacting substance levels and clinicobiochemical parameters in 1,178 middle-aged Japanese men - the Amagasaki Visceral Fat Study , 2011, Nutrition & metabolism.
[18] P. Scherer,et al. Adipose tissue remodeling and obesity. , 2011, The Journal of clinical investigation.
[19] U. Klein,et al. Transcriptional control of adipose lipid handling by IRF4. , 2011, Cell metabolism.
[20] K. Petersen,et al. Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. , 2010, Cell metabolism.
[21] B. Aggarwal,et al. Oxidative stress, inflammation, and cancer: how are they linked? , 2010, Free radical biology & medicine.
[22] M. Matsuda,et al. Human catalase gene is regulated by peroxisome proliferator activated receptor-gamma through a response element distinct from that of mouse. , 2010, Endocrine journal.
[23] Jimmy D Bell,et al. Fat distribution in men of different waist girth, fitness level and exercise habit , 2009, International Journal of Obesity.
[24] D. James,et al. Insulin resistance is a cellular antioxidant defense mechanism , 2009, Proceedings of the National Academy of Sciences.
[25] Masayuki Orimo,et al. A crucial role for adipose tissue p53 in the regulation of insulin resistance , 2009, Nature Medicine.
[26] P. Neufer,et al. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. , 2009, The Journal of clinical investigation.
[27] Philipp E. Scherer,et al. Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI , 2008, Molecular and Cellular Biology.
[28] R. Bibiloni,et al. Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice , 2008, Diabetes.
[29] M. Matsuda,et al. Adipose expression of catalase is regulated via a novel remote PPARgamma-responsive region. , 2008, Biochemical and Biophysical Research Communications - BBRC.
[30] M. Matsuda,et al. Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation , 2007, Diabetes.
[31] P. Froguel,et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions , 2007, Nature Medicine.
[32] I. Lemieux,et al. Abdominal obesity and metabolic syndrome , 2006, Nature.
[33] S. Kihara,et al. Blockade of Angiotensin II type-1 receptor reduces oxidative stress in adipose tissue and ameliorates adipocytokine dysregulation. , 2006, Kidney international.
[34] T. Funahashi,et al. Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome. , 2006, Circulation journal : official journal of the Japanese Circulation Society.
[35] E. Lander,et al. Reactive oxygen species have a causal role in multiple forms of insulin resistance , 2006, Nature.
[36] Remi Rabasa-Lhoret,et al. The metabolically healthy but obese individual presents a favorable inflammation profile. , 2005, The Journal of clinical endocrinology and metabolism.
[37] P. Iyengar,et al. Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy , 2005, Nature Medicine.
[38] S. Simpson. Of Mice . . . , 2004, Science.
[39] Morihiro Matsuda,et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. , 2004, The Journal of clinical investigation.
[40] L. Glimcher,et al. Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes , 2004, Science.
[41] H. Towle,et al. Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes* , 2004, Journal of Biological Chemistry.
[42] M. Desai,et al. Obesity is associated with macrophage accumulation in adipose tissue. , 2003, The Journal of clinical investigation.
[43] U. Smith,et al. Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects* , 2003, Journal of Biological Chemistry.
[44] Hitoshi Shimano,et al. Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes DOI 10.1194/jlr.M100417-JLR200 , 2002, Journal of Lipid Research.
[45] M. Matsuda,et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 , 2002, Nature Medicine.
[46] E. A. Sims,et al. Are there persons who are obese, but metabolically healthy? , 2001, Metabolism: clinical and experimental.
[47] M. Lazar,et al. The hormone resistin links obesity to diabetes , 2001, Nature.
[48] T. Burris,et al. PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes. , 1999, Biochemical and biophysical research communications.
[49] M. Lean,et al. Effects of a thiazolidinedione compound on body fat and fat distribution of patients with type 2 diabetes. , 1999, Diabetes care.
[50] R. Hammer,et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. , 1998, Genes & development.
[51] S. Kiechl,et al. Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. , 1998, Diabetes.
[52] K. Uysal,et al. Protection from obesity-induced insulin resistance in mice lacking TNF-α function , 1997, Nature.
[53] E. Ferrannini,et al. Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). , 1997, The Journal of clinical investigation.
[54] J. Morrow,et al. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[55] E. Ferrannini,et al. Insulin Resistance and Hypersecretion in Obesity , 2013 .
[56] Karen Gallagher-Dorval,et al. Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity. , 2011, Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.
[57] Jianrong Han,et al. Nutrition & Metabolism Modulation of Adipocyte Lipogenesis by Octanoate: Involvement of Reactive Oxygen Species , 2006 .
[58] T. Awata,et al. The ligands/activators for peroxisome proliferator-activated receptor α (PPARα) and PPARγ increase Cu2+, Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells , 2001 .
[59] T. Awata,et al. The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. , 2001, Metabolism: clinical and experimental.
[60] K. Uysal,et al. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. , 1997, Nature.