Model studies of blood flow in basilar artery with 3D laser Doppler anemometer

It is proposed an integrated approach to the study of basilar artery blood flow using 3D laser Doppler anemometer for identifying the causes of the formation and development of cerebral aneurysms. Feature of the work is the combined usage of both mathematical modeling and experimental methods. Described the experimental setup and the method of measurement of basilar artery blood flow, carried out in an interdisciplinary laboratory of Hospital Rechts der Isar of Technical University of Munich. The experimental setup used to simulate the blood flow in the basilar artery and to measure blood flow characteristics using 3D laser Doppler anemometer (3D LDA). Described a method of numerical studies carried out in Tambov State Technical University and the Bakoulev Center for Cardiovascular Surgery. Proposed an approach for sharing experimental and numerical methods of research to identify the causes of the basilar artery aneurysms.

[1]  Frederick R. Haselton,et al.  Flow visualization of steady streaming in oscillatory flow through a bifurcating tube , 1982, Journal of Fluid Mechanics.

[2]  R C Schroter,et al.  Proposal of a shear dependent mass transfer mechanism for atherogenesis. , 1971, Clinical science.

[3]  Dieter W. Liepsch,et al.  Hemodynamic stress in terminal saccular aneurysms: A laser-doppler study , 2005, Heart and Vessels.

[4]  D. Liepsch An introduction to biofluid mechanics--basic models and applications. , 2002, Journal of biomechanics.

[5]  D. Ku,et al.  Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation: Positive Correlation between Plaque Location and Low and Oscillating Shear Stress , 1985, Arteriosclerosis.

[6]  D. Liepsch,et al.  MATHEMATICAL MODELING OF BLOOD FLOW IN BASILAR ARTERY BIFURCATION REGION , 2014 .

[7]  D D Duncan,et al.  Effects of arterial compliance and non-Newtonian rheology on correlations between intimal thickness and wall shear. , 1992, Journal of biomechanical engineering.

[8]  K. Hayashi,et al.  An LDA and flow visualization study of pulsatile flow in an aortic bifurcation model. , 1995, Biorheology.

[9]  C. M. Rodkiewicz,et al.  Flow in Large Arteries , 1983 .

[10]  Fundamental flow studies in models of human arteries. , 1993, Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering.

[11]  D. Liepsch,et al.  Experimental flow studies in an elastic Y-model. , 2003, Technology and health care : official journal of the European Society for Engineering and Medicine.

[12]  J. Tarbell,et al.  Nonlinear analysis of oscillatory flow, with a nonzero mean, in an elastic tube (artery). , 1995, Journal of biomechanical engineering.

[13]  M. Motomiya,et al.  Flow visualization in isolated transparent natural blood vessels. , 1983, Biorheology.

[14]  R. T. Eppink,et al.  Study of stress concentration in the walls of the bovine coronary arterial branch. , 1990, Journal of biomechanics.