Theoretical Backgrounds of Flow Analysis

I. INTRODUCTION A. What Is Flow Analysis? To most workers in the field of flow analysis it appears to be self-explanatory that what they are doing is flow analysis (FA), and they will easily quote many advantages of their system. Nevertheless, it is not easy to properly define what flow analysis is. Even more difficult is defending its advantages against other semiautomatic or automatic analysis methods, in general, because of the wide variety and the fast development of both FA and other instrumentation. A very broad definition of FA might be that in flow analysis the transport of the sample from the place of sampling to the waste (or back to the sampling area in case of recirculation) through stages of various kinds of manipulation like separation, chemical reaction, heating or cooling, detection, etc. is done by imparting the sample or an aliquot of it into a flowing stream. The flow moves the sample through the spatially separated stages of the analysis process in an automatic way.

[1]  H. Mottola,et al.  Novel approach to reaction-rate based determinations by use of transient redox effects , 1975 .

[2]  K K Stewart,et al.  Flow-injection analysis: A review of its early history. , 1981, Talanta.

[3]  M. Golay,et al.  Dispersion of peaks by short straight open tubes in liquid chromatography systems , 1981 .

[4]  Ernő Pungor,et al.  Application of silicone rubber-based graphite electrodes for continuous flow measurements : Part II. Voltammetric study of active substances injected into electrolyte streams , 1970 .

[5]  H. Mottola,et al.  Kinetics in continuous flow sample processing Chemical Contributions to Dispersion in Flow-Injection Techniques , 1984 .

[6]  R. S. Deelder,et al.  Evaluation and comparison of reaction detectors , 1983 .

[7]  H. Pardue,et al.  Kinetic treatment of unsegmented flow systems : Part 3. Flow-injection system with gradient chamber evaluated with a linearly responding detector , 1986 .

[8]  H. Diebler,et al.  Capsule chemistry technology for high-speed clinical chemistry analyses. , 1985, Clinical chemistry.

[9]  Kent K. Stewart,et al.  Automated titrations: the use of automated multiple flow injection analysis for the titration of discrete samples , 1981, The Journal of automatic chemistry.

[10]  J. Tyson Peak width and reagent dispersion in flow injection analysis , 1986 .

[11]  Henrik Pedersen,et al.  Axial dispersion in a segmented gas-liquid flow , 1981 .

[12]  K. Stewart,et al.  Exponential dilution chambers for scale expansion in flow injection analysis , 1982 .

[13]  G. Gerhardt,et al.  Determination of diffusion coefficients by flow injection analysis , 1982 .

[14]  H. Mottola,et al.  Repetitive determination of isonicotinic acid hydrazide in flow-through systems by series reactions. , 1977, Analytical chemistry.

[15]  G. Taylor Dispersion of soluble matter in solvent flowing slowly through a tube , 1953, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.

[16]  G. Beecher,et al.  Laminar-flow bolus shapes in flow injection analysis , 1986 .

[17]  L. R. Snyder,et al.  Dispersion in segmented flow through glass tubing in continuous-flow analysis: the ideal model , 1976 .

[18]  R. Trivedi,et al.  Axial dispersion in laminar flow in helical coils , 1975 .

[19]  T. S. Stevens,et al.  Packed hollow fiber suppressors for ion chromatography , 1982 .

[20]  J. Ruzicka,et al.  The principles and theory of high-speed titrations by flow injection analysis , 1981 .

[21]  H. Poppe,et al.  Some theoretical aspects of flow injection analysis , 1980 .

[22]  L. Skeggs An automatic method for colorimetric analysis. , 1957, American journal of clinical pathology.

[23]  U. Neue,et al.  Reaction detector with three dimensional coiled open tubes in HPLC , 1982 .

[24]  B. Karlberg,et al.  Extraction based on the flow-injection principle , 1980 .

[25]  R. W. Frei,et al.  Solvent segmentation in liquid chromatography —application to photochemical reactions detectors☆ , 1981 .

[26]  J. Janata,et al.  Combination of flow injection analysis and voltammetry , 1982 .

[27]  R. W. Frei,et al.  Comparison of liquid segmented with nonsegmented flow systems in post-column reactors for liquid chromatography , 1982 .

[28]  R. W. Frei,et al.  Post-column reaction detectors for high-performance liquid chromatography , 1985 .

[29]  D. Scott,et al.  The measurement of transport coefficients in gas-solid heterogeneous reactions , 1974 .

[30]  H. Poppe,et al.  Optimal design of tubular and packed-bed homogeneous flow chemical reactors for column liquid chromatography , 1980 .

[31]  H. Poppe,et al.  Dispersion in open tubes and tubes packed with large glass beads , 1981 .

[32]  J. M. Harris Flow Injection of Ultratrace Level Samples into Laser-Based Detectors , 1982 .

[33]  B. Fleet,et al.  Gradient titration. Novel approach to continuous monitoring using ion-selective electrodes , 1974 .

[34]  B. Fields,et al.  Kinetic treatment of unsegmented flow systems : Part 1. Subjective and semiquantitative evaluations of flow-injection systems with gradient chamber , 1981 .

[35]  Ernő Pungor,et al.  A simple continuous method for calibration and measurement with ion-selective electrodes , 1976 .

[36]  S. M. Abicht Controlled dynamic titrator , 1980 .

[37]  K. Stewart Time-based flow injection analysis , 1986 .

[38]  Flow injection analysis , 1978 .

[39]  B. Fields,et al.  Kinetic treatment of unsegmented flow systems : Part 2. Detailed Treatment of Flow-Injection Systems with Gradient Chamber , 1981 .

[40]  G. Beecher,et al.  Determination of first-order reaction rate constants by flow injection analysis , 1984 .

[41]  M. Golay,et al.  Early phases of the dispersion of a sample injected in poiseuille flow , 1979 .

[42]  R. R. Cole,et al.  Kinetic parameters of continuous flow analysis. , 1967, Clinical chemistry.

[43]  G. Beecher,et al.  Dispersion and diffusion coefficients in flow injection analysis , 1984 .

[44]  J. Ruzicka,et al.  Flow injection analysis : Part IX. A New Approach to Continuous Flow Titrations , 1977 .

[45]  John W. Dolan,et al.  Introduction to modern liquid chromatography , 1974 .

[46]  C. Pennock,et al.  Practical considerations in kinetics of continuous flow analysis. , 1970, Clinica chimica acta; international journal of clinical chemistry.

[47]  H. Mottola,et al.  Dispersion in continuous-flow sample processing , 1983 .

[48]  R. Scott,et al.  A vapour dilution system for detector calibration. , 1963, Journal of chromatography.

[49]  D. Higgs,et al.  Laminar dispersion in flow-injection analysis. , 1981, Talanta.

[50]  G. Nagy,et al.  A detailed study of sample injection into flowing streams with potentiometric detection , 1978 .

[51]  L. Snyder Reaction colorimeters as detectors in high-performance liquid chromatography , 1976 .

[52]  J. Sirs,et al.  Influence of diffusion on dispersion of indicators in blood flow. , 1973, Journal of applied physiology.

[53]  H. Poppe,et al.  A possible approach to the optimization of flow injectin analysis , 1983 .

[54]  J. L. Duda,et al.  Numerical Simulation of Solute Dispersion in Laminar Tube Flow , 1980 .

[55]  M. Gisin,et al.  Hydrodynamically limited precision of gradient techniques in flow injection analysis , 1986 .

[56]  R. Tijssen Axial dispersion and flow phenomena in helically coiled tubular reactors for flow analysis and chromatography , 1980 .

[57]  G. Nagy,et al.  The use of precipitate based silicone rubber ion-selective electrodes and silicone rubber based graphite voltammetric electrodes in continuous analysis. A review , 1974 .

[58]  M. Margoshes Pumping pressure and reagent consumption in flow injection analysis. Reply to comments , 1977 .

[59]  B. Fleet,et al.  A semi-automated single-cell gradient-titration system, using ion-selective electrodes as end-point sensors. , 1980, Talanta.

[60]  H. Poppe,et al.  Kinetics in a single bead string reactor for flow injection analysis , 1984 .

[61]  H. Mottola,et al.  Chemical kinetic contributions to practical dispersion in flow injection analysis , 1981 .

[62]  R. S. Deelder,et al.  Dispersion phenomena in reactors for flow analysis , 1980 .

[63]  M. Margoshes Pumping pressure and reagent consumption in continuous flow analysis with unsegmented reaction streams , 1977 .

[64]  I. Halasz,et al.  Mass transfer in ideal and geometrically deformed open tubes. , 1979 .

[65]  R. W. Frei,et al.  Use of non-segmented flow, post-columns reaction detection with miniaturized HPLC systems , 1983 .

[66]  W. Gill,et al.  Laminar dispersion in capillaries: Part I. Mathematical analysis , 1965 .

[67]  D. Betteridge,et al.  A random walk simulation of flow injection analysis , 1984 .

[68]  L. Snyder Continuous-flow analysis: present and future , 1980 .

[69]  G. Horvai,et al.  Injection techniques in dynamic flow-through analysis with electroanalytical sensors , 1979 .

[70]  H. Mosbaek,et al.  Exchange of comments: Pumping pressure and reagent consumption in flow injection analysis , 1977 .

[71]  J. Knox,et al.  The Performance of Packings in High Speed Liquid Chromatography II. ZIPAX® The Effect of Particle Size , 1972 .

[72]  J. Ruzicka,et al.  Flow injection analyses , 1975 .

[73]  W. Gill,et al.  Laminar dispersion in capillaries: Part IV. The slug stimulus , 1967 .

[74]  G. Nagy,et al.  Novel programmed coulometric titration technique. Chloride determination in streaming solutions , 1975 .

[75]  C. Simpson,et al.  Determination of the Extra Column Dispersion Occurring in the Different Components of a Chromatographic System , 1982 .