An improved ANN controller is presented inspired from hormone modulation function. This ANN controller consists of the main ANN controller and the conventional controller. To increase the learning efficiency, the slop of the excitation function is changed by the correcting parameters according to the hormone modulation law. To improve the control accuracy, we chose the accumulation of control error during the regulating process. And to avoid the integrated saturation, we judge the input of BP based on the absolute value of error. The main ANN controller adjusts the control input of the secondary conventional controller. To testify the effectiveness of the improved ANN controller, we apply it on the experiment device of offshore oil platform. The results show that the improved ANN controller has better control performance than the conventional controller and the normal ANN controller.