Rotura prematura de membranas en embarazos pretérmino en un centro hospitalario en Puerto Cabello, Venezuela

Objetive: To determine the incidence of pre-term pregnancies with PrOM, maternal characteristics and perinatal impact. Sitting: Hospital “dr. Adolfo Prince Lara “, Puerto Cabello, Carabobo State, Venezuela. Methods: A retrospective descriptive analysis in 7749 pregnancies occurred during 2005-2007, of which 185 had pre-term pregnancy with PrOM, there was one every 40 pregnancies. Results: The incidence was 2.02% (185/7749). Neighborhood residents predominated patients (64.86%), unmarried (59.46%) of 24 years and less (38.38%), history of previous cesarean section (6.94%) and smokers (6.48%). With gestations between V-II (52.97%), gestational age 34-36 weeks (57.3%), cesarean delivery rate at admission (45.95%), diagnosis on admission PrOM (71.28%) , initial rate of cesarean delivery (45.95%). The diagnostic method speculum (55.68%), treated with antibiotics, corticosteroids and cesarean section (40%), ant ibiot ics and caesarean section (21.08%). Newborn state, male infants (53.51%), weight 2000-2499 g (49.73%), height 50-54 cm (58.92%) and index Apgar ≤ 6 (35.68%). Neonatal morbidity 14.59 % (27/159), neonatal mortality 7.56 % (14/159), and maternal morbidity 21.08 % (38/185). Conclusion: PrOM in the preterm pregnancy presented an Conclusión: La

[1]  P. Faneite,et al.  Estado neonatal en prematurez: 2005-2007 , 2008 .

[2]  M. Kaminski,et al.  Prolonged sedation and/or analgesia and 5-year neurodevelopment outcome in very preterm infants: results from the EPIPAGE cohort. , 2008, Archives of pediatrics & adolescent medicine.

[3]  G. Breart,et al.  Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study , 2008, The Lancet.

[4]  M. Kaminski,et al.  Prevalence and associated factors of minor neuromotor dysfunctions at age 5 years in prematurely born children: the EPIPAGE Study. , 2007, Archives of pediatrics & adolescent medicine.

[5]  P. Faneite,et al.  Nacimientos según tipo de asistencia obstétrica. Hospital Dr. Adolfo Prince Lara, Puerto Cabello, Estado Carabobo, 1969-2004 , 2007 .

[6]  P. Faneite,et al.  Prematurez: Resultados perinatales , 2006 .

[7]  Y. D. L. Torre,et al.  Morbimortalidad perinatal de la rotura prematura de membrana en el embarazo pretérmino , 2006 .

[8]  S. Kilpatrick,et al.  Risk factors for previable premature rupture of membranes or advanced cervical dilation: a case control study. , 2006, American journal of obstetrics and gynecology.

[9]  D. Hill,et al.  Preterm premature rupture of membranes: diagnosis and management. , 2006, American family physician.

[10]  B. Mercer,et al.  Periviable birth at 20 to 26 weeks of gestation: proximate causes, previous obstetric history and recurrence risk. , 2005, American journal of obstetrics and gynecology.

[11]  H. Simhan,et al.  Preterm premature rupture of membranes: diagnosis, evaluation and management strategies , 2005, BJOG : an international journal of obstetrics and gynaecology.

[12]  F. Bello,et al.  ß-hCG en fluidos vaginales como marcador de rotura prematura de membranas , 2003 .

[13]  S. Kenyon,et al.  Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial , 2001, The Lancet.

[14]  P. Meis,et al.  Fetal Membrane Histology in Preterm Premature Rupture of Membranes: Comparison to Controls, and between Antibiotic and Placebo Treatment , 1999, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

[15]  Abhik Das,et al.  ANTIBIOTIC THERAPY FOR REDUCTION OF INFANT MORBIDITY AFTER PRETERM PREMATURE RUPTURE OF THE MEMBRANES : A RANDOMIZED CONTROLLED TRIAL , 1998 .

[16]  D. Ferris.  Management of bacterial vaginosis during pregnancy. , 1998, American family physician.

[17]  R. Romero,et al.  Pathogenesis of preterm labor and preterm premature rupture of membranes associated with intraamniotic infection. , 1997, Infectious disease clinics of North America.

[18]  I. Merkatz,et al.  Preterm delivery and low birth weight--a dire legacy. , 1995, The New England journal of medicine.

[19]  K. Arheart,et al.  Antimicrobial therapy in expectant management of preterm premature rupture of the membranes , 1995, The Lancet.

[20]  D A Savitz,et al.  Epidemiologic characteristics of preterm delivery: etiologic heterogeneity. , 1991, American journal of obstetrics and gynecology.

[21]  P. Meis,et al.  Causes of low birth weight births in public and private patients. , 1987, American journal of obstetrics and gynecology.

[22]  J. Dungan,et al.  Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study , 2009 .

[23]  ACOG Committee Opinion No. 402: Antenatal corticosteroid therapy for fetal maturation. , 2008, Obstetrics and gynecology.

[24]  H. Powers,et al.  Reduced Collagen and Ascorbic Acid Concentrations and Increased Proteolytic Susceptibility with Prelabor Fetal Membrane Rupture in Women1 , 2005, Biology of reproduction.

[25]  G. Thurnau,et al.  Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. A randomized controlled trial. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. , 1997, JAMA.

[26]  G. Ramírez Cueto,et al.  [Premature rupture of membranes]. , 1975, Ginecologia y obstetricia de Mexico.