GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha.

[1]  M. Montminy,et al.  The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism , 2005, Nature.

[2]  Jiandie D. Lin,et al.  Nutritional Regulation of Hepatic Heme Biosynthesis and Porphyria through PGC-1α , 2005, Cell.

[3]  Christoph Handschin,et al.  Metabolic control through the PGC-1 family of transcription coactivators. , 2005, Cell metabolism.

[4]  L. Guarente,et al.  Calorie restriction, SIRT1 and metabolism: understanding longevity , 2005, Nature Reviews Molecular Cell Biology.

[5]  Wilhelm Haas,et al.  Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 , 2005, Nature.

[6]  John R Yates,et al.  Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions , 2004, Science.

[7]  B. Rogina,et al.  Sir2 mediates longevity in the fly through a pathway related to calorie restriction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Mark H. Ellisman,et al.  Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei , 2004, The Journal of cell biology.

[9]  Victor G Corces,et al.  Boundary elements and nuclear organization , 2004, Biology of the cell.

[10]  P. So,et al.  Nuclear receptor corepressor RIP140 regulates fat accumulation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[11]  Marc Montminy,et al.  PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 , 2004, Nature Medicine.

[12]  Jennifer M. A. Tullet,et al.  Characterization of Four Autonomous Repression Domains in the Corepressor Receptor Interacting Protein 140* , 2004, Journal of Biological Chemistry.

[13]  J. Flier.  Obesity Wars Molecular Progress Confronts an Expanding Epidemic , 2004, Cell.

[14]  B. Spiegelman,et al.  Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. , 2003, Molecular cell.

[15]  A. Pandey,et al.  A proteomic approach for quantitation of phosphorylation using stable isotope labeling in cell culture. , 2003, Analytical chemistry.

[16]  D. Sinclair,et al.  Longevity Regulation in Saccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin , 2003, Microbiology and Molecular Biology Reviews.

[17]  David L. Spector,et al.  Nuclear speckles: a model for nuclear organelles , 2003, Nature Reviews Molecular Cell Biology.

[18]  Jiandie D. Lin,et al.  Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells* , 2003, Journal of Biological Chemistry.

[19]  M. Daly,et al.  PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.

[20]  Yvonne A. Evrard,et al.  c-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation* , 2003, Journal of Biological Chemistry.

[21]  Bruce M. Spiegelman,et al.  Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction , 2003, Nature.

[22]  M. Kagey,et al.  The Polycomb Protein Pc2 Is a SUMO E3 , 2003, Cell.

[23]  P. Puigserver,et al.  Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[24]  V. Ogryzko,et al.  Immunoaffinity purification of mammalian protein complexes. , 2003, Methods in enzymology.

[25]  J. Workman,et al.  Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes , 2002, Cell.

[26]  D. Accili,et al.  The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. , 2001, The Journal of clinical investigation.

[27]  A. Kralli,et al.  PGC-1, a versatile coactivator , 2001, Trends in Endocrinology & Metabolism.

[28]  B. Chait,et al.  Human STAGA Complex Is a Chromatin-Acetylating Transcription Coactivator That Interacts with Pre-mRNA Splicing and DNA Damage-Binding Factors In Vivo , 2001, Molecular and Cellular Biology.

[29]  Marc Montminy,et al.  CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 , 2001, Nature.

[30]  Guillaume Adelmant,et al.  Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 , 2001, Nature.

[31]  J. Gustafsson,et al.  Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140. , 2001, Molecular endocrinology.

[32]  A. Saltiel.  New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes , 2001, Cell.

[33]  R. Evans,et al.  Identification of a nuclear domain with deacetylase activity. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[34]  Jun Qin,et al.  Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis , 2000, Cell.

[35]  P. Puigserver,et al.  Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. , 2000, Molecular cell.

[36]  G. Shulman,et al.  On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance , 2022 .

[37]  Guillaume Adelmant,et al.  Activation of PPARγ coactivator-1 through transcription factor docking , 1999 .

[38]  K. Howe,et al.  Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies. , 1998, American journal of human genetics.

[39]  J. Gustafsson,et al.  Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene , 1990, Molecular and cellular biology.

[40]  R. Roeder,et al.  Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. , 1983, Nucleic acids research.

[41]  H. Krebs,et al.  The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. , 1967, The Biochemical journal.