Gene regulation by steroid hormones

[1]  B. O’Malley,et al.  Regulation of progesterone receptor-mediated transcription by phosphorylation. , 1990, Science.

[2]  M. Beato,et al.  Structural features of a regulatory nucleosome. , 1990, Journal of molecular biology.

[3]  H. Richard-Foy,et al.  Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[4]  C. Hutchison,et al.  Structural determinants of a glucocorticoid receptor recognition element. , 1990, Molecular endocrinology.

[5]  K. Dahlman-Wright,et al.  The steroid-binding properties of recombinant glucocorticoid receptor: A putative role for heat shock protein hsp90 , 1990, The Journal of Steroid Biochemistry and Molecular Biology.

[6]  J. Schwabe,et al.  Solution structure of the DNA-binding domain of the oestrogen receptor. , 1990, Nature.

[7]  P. Chambon,et al.  Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes. , 1990, The Journal of biological chemistry.

[8]  S. Lindquist,et al.  Reduced levels of hsp90 compromise steroid receptor action in vivo , 1990, Nature.

[9]  I. Issemann,et al.  Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators , 1990, Nature.

[10]  T. Perlmann,et al.  Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element. , 1990, The Journal of biological chemistry.

[11]  S. Fawell,et al.  A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor , 1990, Molecular and cellular biology.

[12]  G. Hager,et al.  Sequence-specific DNA binding by glucocorticoid receptor "zinc finger peptides". , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[13]  B. O’Malley,et al.  Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites. , 1990, The Journal of biological chemistry.

[14]  M. Karin,et al.  Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction , 1990, Cell.

[15]  Stephan Gebel,et al.  Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone , 1990, Cell.

[16]  S. Kliewer,et al.  Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor , 1990, Cell.

[17]  K. Yamamoto,et al.  Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. , 1990, Science.

[18]  F. C. Lucibello,et al.  Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB. , 1990, The EMBO journal.

[19]  M. Beato,et al.  Binding of the glucocorticoid receptor induces a topological change in plasmids containing the hormone-responsive element of mouse mammary tumor virus. , 1990, DNA and cell biology.

[20]  G. Chalepakis,et al.  Contacts between steroid hormone receptors and thymines in DNA: an interference method. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[21]  K. Dahlman-Wright,et al.  Protein-protein interactions facilitate DNA binding by the glucocorticoid receptor DNA-binding domain. , 1990, The Journal of biological chemistry.

[22]  W. Pratt,et al.  Evidence that the conserved region in the steroid binding domain of the glucocorticoid receptor is required for both optimal binding of hsp90 and protection from proteolytic cleavage. A two-site model for hsp90 binding to the steroid binding domain. , 1990, The Journal of biological chemistry.

[23]  M. Ptashne,et al.  Activators and targets , 1990, Nature.

[24]  K. Yamamoto,et al.  Mapping the HSP90 binding region of the glucocorticoid receptor. , 1990, The Journal of biological chemistry.

[25]  K. Yamamoto,et al.  Solution structure of the glucocorticoid receptor DNA-binding domain. , 1990, Science.

[26]  M. Beato,et al.  Nuclear factor I acts as a transcription factor on the MMTV promoter but competes with steroid hormone receptors for DNA binding. , 1990, The EMBO journal.

[27]  Forman Bm,et al.  Dimerization among nuclear hormone receptors. , 1990 .

[28]  M. Schauer,et al.  Efficient binding of glucocorticoid receptor to its responsive element requires a dimer and DNA flanking sequences. , 1990, DNA and cell biology.

[29]  P Chambon,et al.  Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. , 1990, The EMBO journal.

[30]  J. Gustafsson,et al.  Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment that mediates a delayed secondary response to glucocorticoids in vivo. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[31]  M. Beato,et al.  The uteroglobin promoter contains a noncanonical estrogen responsive element. , 1990, Molecular endocrinology.

[32]  S. Fawell,et al.  Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor , 1990, Cell.

[33]  M. Beato,et al.  Progesterone receptor stimulates transcription of mouse mammary tumour virus in a cell-free system , 1990, Nature.

[34]  M. Beato,et al.  Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter , 1990, Cell.

[35]  W. Pratt,et al.  In contrast to the glucocorticoid receptor, the thyroid hormone receptor is translated in the DNA binding state and is not associated with hsp90. , 1990, The Journal of biological chemistry.

[36]  B. O’Malley.  The steroid receptor superfamily: more excitement predicted for the future. , 1990, Molecular endocrinology.

[37]  G. Chalepakis,et al.  Hormonal induction of transfected genes depends on DNA topology , 1990, Molecular and cellular biology.

[38]  S. Rusconi,et al.  A single DNA‐binding transcription factor is sufficient for activation from a distant enhancer and/or from a promoter position. , 1990, The EMBO journal.

[39]  A. Shimamura,et al.  Histone H1 represses transcription from minichromosomes assembled in vitro , 1989, Molecular and cellular biology.

[40]  N. Webster,et al.  The human estrogen receptor has two independent nonacidic transcriptional activation functions , 1989, Cell.

[41]  P. Godowski,et al.  Steroid receptors. How to be both a receptor and a transcription factor. , 1989, Biochemical pharmacology.

[42]  K. Yamamoto,et al.  Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. , 1989, Genes & development.

[43]  D. Edwards,et al.  Human progesterone receptor complexed with the antagonist RU 486 binds to hormone response elements in a structurally altered form. , 1989, Molecular endocrinology.

[44]  H. Stunnenberg,et al.  Glucocorticoid receptor binds cooperatively to adjacent recognition sites. , 1989, The EMBO journal.

[45]  P. Chambon,et al.  Phosphorylation on tyrosine of in vitro synthesized human estrogen receptor activates its hormone binding. , 1989, Molecular endocrinology.

[46]  G. Ringold,et al.  Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor , 1989, Cell.

[47]  K. Umesono,et al.  Determinants of target gene specificity for steroid/thyroid hormone receptors , 1989, Cell.

[48]  B. O’Malley,et al.  Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements , 1989, Cell.

[49]  P. Chambon,et al.  The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. , 1989, Nucleic acids research.

[50]  F. Auricchio,et al.  Phosphorylation of steroid receptors. , 1989, Journal of steroid biochemistry.

[51]  P. Chambon,et al.  Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element , 1989, Nature.

[52]  M. Schauer,et al.  Binding of hormone accelerates the kinetics of glucocorticoid and progesterone receptor binding to DNA. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[53]  A. Wolffe,et al.  Dominant and specific repression of Xenopus oocyte 5S RNA genes and satellite I DNA by histone H1. , 1989, The EMBO journal.

[54]  P. Chambon,et al.  Expression of active hormone and DNA‐binding domains of the chicken progesterone receptor in E. coli. , 1989, The EMBO journal.

[55]  S. Elgin,et al.  The formation and function of DNase I hypersensitive sites in the process of gene activation. , 1988, The Journal of biological chemistry.

[56]  M. Grunstein,et al.  Nucleosome loss activates yeast downstream promoters in vivo , 1988, Cell.

[57]  B. O’Malley,et al.  Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets. , 1988, Science.

[58]  R. Evans,et al.  Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein , 1988, Cell.

[59]  M. Perricaudet,et al.  Receptors bound to antiprogestin form abortive complexes with hormone responsive elements , 1988, Nature.

[60]  R. Schüle,et al.  Many transcription factors interact synergistically with steroid receptors. , 1988, Science.

[61]  R. Evans,et al.  Multiple and cooperative trans-activation domains of the human glucocorticoid receptor , 1988, Cell.

[62]  M. Beato,et al.  Sequences downstream of the glucocorticoid regulatory element mediate cycloheximide inhibition of steroid induced expression from the rat alpha 1-acid glycoprotein promoter: evidence for a labile transcription factor. , 1988, Molecular endocrinology.

[63]  G. Chalepakis,et al.  A model for hormone receptor binding to the mouse mammary tumour virus regulatory element based on hydroxyl radical footprinting. , 1988, Nucleic acids research.

[64]  G. Schütz,et al.  Synergistic action of the glucocorticoid receptor with transcription factors. , 1988, The EMBO journal.

[65]  P. Chambon,et al.  Genomic organization of the human oestrogen receptor gene. , 1988, The EMBO journal.

[66]  J. Stavenhagen,et al.  An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene , 1988, Cell.

[67]  B. O’Malley,et al.  Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation , 1988, Cell.

[68]  M. Ptashne.  How eukaryotic transcriptional activators work , 1988, Nature.

[69]  P. Chambon,et al.  The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer , 1988, Cell.

[70]  M. Grunstein,et al.  Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast , 1988, Cell.

[71]  P. Chambon,et al.  The N‐terminal DNA‐binding ‘zinc finger’ of the oestrogen and glucocorticoid receptors determines target gene specificity. , 1988, The EMBO journal.

[72]  T. Perlmann,et al.  Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome. , 1988, The EMBO journal.

[73]  K. Yamamoto,et al.  Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene. , 1988, Genes & development.

[74]  K. Yamamoto,et al.  Mammalian glucocorticoid receptor derivatives enhance transcription in yeast. , 1988, Science.

[75]  K. Yamamoto,et al.  Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins. , 1988, Science.

[76]  K. Yamamoto,et al.  The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain , 1988, Nature.

[77]  Mark Ptashne,et al.  Negative effect of the transcriptional activator GAL4 , 1988, Nature.

[78]  S. Rusconi,et al.  Metal binding ‘finger’ structures in the glucocorticoid receptor defined by site‐directed mutagenesis. , 1988, The EMBO journal.

[79]  C. Glass,et al.  The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements , 1988, Cell.

[80]  J D Baxter,et al.  Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. , 1988, Science.

[81]  P. Chambon,et al.  The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function , 1988, Cell.

[82]  P. Chambon,et al.  The human oestrogen receptor functions in yeast , 1988, Nature.

[83]  M. Grunstein,et al.  Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae. , 1988, The EMBO journal.

[84]  A. E. Sippel,et al.  A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin. , 1988, The EMBO journal.

[85]  P. Webb,et al.  Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus. , 1988, Nucleic acids research.

[86]  M. Pfahl,et al.  A new retinoic acid receptor identified from a hepatocellular carcinoma , 1988, Nature.

[87]  L. Poellinger,et al.  Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state , 1988, Nature.

[88]  M. Karin,et al.  Progesterone induction of metallothionein-IIA gene expression. , 1988, Molecular endocrinology.

[89]  A. Cato,et al.  Mineralocorticoid regulation of transcription of transfected mouse mammary tumor virus DNA in cultured kidney cells , 1988, The Journal of cell biology.

[90]  A. Munck,et al.  Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells. , 1988, Biochemistry.

[91]  B. Persson,et al.  Identification of hormone-interacting amino acid residues within the steroid-binding domain of the glucocorticoid receptor in relation to other steroid hormone receptors. , 1988, The Journal of biological chemistry.

[92]  R. Evans,et al.  The steroid and thyroid hormone receptor superfamily. , 1988, Science.

[93]  P. Chambon,et al.  The N-terminal region of the chicken progesterone receptor specifies target gene activation , 1988, Nature.

[94]  G. Chalepakis,et al.  Differential gene activation by glucocorticoids and progestins through the hormone regulatory element of mouse mammary tumor virus , 1988, Cell.

[95]  H. Ponta,et al.  DNA sequences outside the receptor‐binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones. , 1988, The EMBO journal.

[96]  Chawnshang Chang,et al.  Molecular cloning of human and rat complementary DNA encoding androgen receptors. , 1988, Science.

[97]  H. Willard,et al.  Cloning of human androgen receptor complementary DNA and localization to the X chromosome. , 1988, Science.

[98]  M. Rosenfeld,et al.  Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain , 1988, Cell.

[99]  R. Schüle,et al.  Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor , 1988, Nature.

[100]  G. McKnight,et al.  The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen. , 1988, Molecular endocrinology.

[101]  G. Hager,et al.  Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts. , 1988, Nucleic acids research.

[102]  R. Evans,et al.  Zinc fingers: Gilt by association , 1988, Cell.

[103]  R. Evans,et al.  Identification of a new class of steroid hormone receptors , 1988, Nature.

[104]  R. Evans,et al.  A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex. , 1988, The Journal of biological chemistry.

[105]  P. Chambon,et al.  Functional domains of the human estrogen receptor , 1987, Cell.

[106]  Pierre Chambon,et al.  A human retinoic acid receptor which belongs to the family of nuclear receptors , 1987, Nature.

[107]  V. Giguère,et al.  Identification of a receptor for the morphogen retinoic acid , 1987, Nature.

[108]  B. O’Malley,et al.  Structure of the chromosomal chicken progesterone receptor gene. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[109]  J. Drouin,et al.  Pro‐opiomelanocortin gene: A model for negative regulation of transcription by glucocorticoids , 1987, Journal of cellular biochemistry.

[110]  G. Schütz,et al.  A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[111]  P. Mellon,et al.  Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements , 1987, Molecular and cellular biology.

[112]  K. Yamamoto,et al.  Two signals mediate hormone‐dependent nuclear localization of the glucocorticoid receptor. , 1987, The EMBO journal.

[113]  G. Schütz,et al.  Oestrogen and glucocorticoid responsive elements are closely related but distinct , 1987, Nature.

[114]  Jun Ma,et al.  A new class of yeast transcriptional activators , 1987, Cell.

[115]  R. Evans,et al.  Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. , 1987, Science.

[116]  J. Jameson,et al.  Cyclic AMP responsiveness of human gonadotropin-alpha gene transcription is directed by a repeated 18-base pair enhancer. Alpha-promoter receptivity to the enhancer confers cell-preferential expression. , 1987, The Journal of biological chemistry.

[117]  R. King.  Structure and function of steroid receptors. , 1987, The Journal of endocrinology.

[118]  J. Jameson,et al.  trans-acting factors interact with a cyclic AMP response element to modulate expression of the human gonadotropin alpha gene , 1987, Molecular and cellular biology.

[119]  E. Baulieu,et al.  Antiglucocorticosteroid effects suggest why steroid hormone is required for receptors to bind DNA in vivo but not in vitro , 1987, Nature.

[120]  H. Richard-Foy,et al.  Sequence‐specific positioning of nucleosomes over the steroid‐inducible MMTV promoter. , 1987, The EMBO journal.

[121]  D. Housman,et al.  Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. , 1987, Science.

[122]  S. Rudikoff,et al.  Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate. , 1987, The Journal of biological chemistry.

[123]  J. Gustafsson,et al.  Domain structure of the glucocorticoid receptor protein. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[124]  M. Beato,et al.  Partial overlapping of binding sequences for steroid hormone receptors and DNaseI hypersensitive sites in the rabbit uteroglobin gene region. , 1987, Nucleic acids research.

[125]  C. Calladine,et al.  Sequence-specific positioning of core histones on an 860 base-pair DNA. Experiment and theory. , 1987, Journal of molecular biology.

[126]  K. Yamamoto,et al.  Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. , 1987, The EMBO journal.

[127]  J. Nowock,et al.  Interaction of the TGGCA‐binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus. , 1987, The EMBO journal.

[128]  K. Yamamoto,et al.  Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation. , 1987, Science.

[129]  R. Evans,et al.  Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor , 1987, Cell.

[130]  B. Gloss,et al.  Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene , 1987, Cell.

[131]  E. Vallen,et al.  Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[132]  F. Galibert,et al.  Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA. , 1987, Biochemical and biophysical research communications.

[133]  M. Haussler,et al.  Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. , 1987, Science.

[134]  B. Gloss,et al.  Glucocorticoid induction of the rat tryptophan oxygenase gene is mediated by two widely separated glucocorticoid‐responsive elements. , 1987, The EMBO journal.

[135]  H. Ponta,et al.  The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region. , 1987, The EMBO journal.

[136]  G. Hager,et al.  Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo , 1987, Cell.

[137]  R. Evans,et al.  The c-erb-A gene encodes a thyroid hormone receptor , 1986, Nature.

[138]  M. Beato,et al.  Steroid-free glucocorticoid receptor binds specifically to mouse mammary tumour virus DNA , 1986, Nature.

[139]  H. Beug,et al.  The c-erb-A protein is a high-affinity receptor for thyroid hormone , 1986, Nature.

[140]  Pierre Chambon,et al.  Carcinogenesis: A superfamily of potentially oncogenic hormone receptors , 1986, Nature.

[141]  C. Le Page,et al.  Sequence‐specific DNA binding of the progesterone receptor to the uteroglobin gene: effects of hormone, antihormone and receptor phosphorylation. , 1986, The EMBO journal.

[142]  E. Milgrom,et al.  Cloning and sequence analysis of rabbit progesterone-receptor complementary DNA. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[143]  H. Drew,et al.  Sequence periodicities in chicken nucleosome core DNA. , 1986, Journal of molecular biology.

[144]  M. Beato,et al.  Molecular model of the interaction between the glucocorticoid receptor and the regulatory elements of inducible genes. , 1986, DNA.

[145]  A. Hinnen,et al.  Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activating DNA elements. , 1986, The EMBO journal.

[146]  W Hörz,et al.  Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast. , 1986, The EMBO journal.

[147]  J. Gustafsson,et al.  Stoichiometric analysis of the specific interaction of the glucocorticoid receptor with DNA. , 1986, The Journal of biological chemistry.

[148]  M. Beato,et al.  The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. , 1986, The EMBO journal.

[149]  P. Chambon,et al.  Localisation of the oestradiol‐binding and putative DNA‐binding domains of the human oestrogen receptor. , 1986, The EMBO journal.

[150]  R. Evans,et al.  Functional domains of the human glucocorticoid receptor , 1986, Cell.

[151]  Mark Ptashne,et al.  Gene regulation by proteins acting nearby and at a distance , 1986, Nature.

[152]  B. O’Malley,et al.  Molecular cloning of the chicken progesterone receptor , 1986, Science.

[153]  P. Chambon,et al.  Cloning of the chicken progesterone receptor. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[154]  B. Dombroski,et al.  Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[155]  R. King,et al.  Androgen regulation by the long terminal repeat of mouse mammary tumor virus , 1986, Molecular and cellular biology.

[156]  K. Yamamoto,et al.  Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA , 1986, Cell.

[157]  M. Beato,et al.  Glucocorticoid responsiveness of the transcriptional enhancer of Moloney Murine Sarcoma Virus , 1986, Cell.

[158]  L. Maquat,et al.  Localization of DNA sequences involved in dexamethasone-dependent expression of the rat alpha 1-acid glycoprotein gene , 1986, Molecular and cellular biology.

[159]  D. von der Ahe,et al.  Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[160]  K. Yamamoto,et al.  Two different factors act separately or together to specify functionally distinct activities at a single transcriptional enhancer , 1986, Molecular and cellular biology.

[161]  P. Argos,et al.  Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A , 1986, Nature.

[162]  P. Chambon,et al.  Steroid hormone dependence of four DNase I‐hypersensitive regions located within the 7000‐bp 5′‐flanking segment of the ovalbumin gene. , 1986, The EMBO journal.

[163]  R. Evans,et al.  Primary structure and expression of a functional human glucocorticoid receptor cDNA , 1985, Nature.

[164]  P. Chambon,et al.  Cloning of the human estrogen receptor cDNA. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[165]  M. Beato,et al.  Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters , 1985, Nature.

[166]  J D Baxter,et al.  Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene , 1985, Molecular and cellular biology.

[167]  A Klug,et al.  Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes. , 1985, The EMBO journal.

[168]  P. Feigelson,et al.  Rat alpha 1-acid glycoprotein. Gene sequence and regulation by glucocorticoids in transfected L-cells. , 1985, The Journal of biological chemistry.

[169]  M. Beato,et al.  The nucleotide sequences recognized by the glucocorticoid receptor in the rabbit uteroglobin gene region are located far upstream from the initiation of transcription. , 1984, The EMBO journal.

[170]  L. Dixon,et al.  Initiation of translation of the cauliflower mosaic virus genome from a polycistronic mRNA: evidence from deletion mutagenesis , 1984, The EMBO journal.

[171]  A. E. Sippel,et al.  Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme gene , 1984, Nature.

[172]  W. Richardson,et al.  Sequence requirements for nuclear location of simian virus 40 large-T antigen , 1984, Nature.

[173]  G. Schütz,et al.  Tissue‐specific DNaseI hypersensitive sites in the 5′‐flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes. , 1984, The EMBO journal.

[174]  Keith R. Yamamoto,et al.  Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element , 1984, Cell.

[175]  J. Taylor,et al.  Glucocorticoid-mediated induction of alpha 1-acid glycoprotein: evidence for hormone-regulated RNA processing. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[176]  M. Beato,et al.  Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding , 1984, Cell.

[177]  M. Beato,et al.  Contacts between hormone receptor and DNA double helix within a glucocorticoid regulatory element of mouse mammary tumor virus. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[178]  J. Gustafsson,et al.  Characterization of the purified activated glucocorticoid receptor from rat liver cytosol. , 1984, The Journal of biological chemistry.

[179]  M. Karin,et al.  Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene , 1984, Nature.

[180]  K. Yamamoto,et al.  Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region , 1983, Cell.

[181]  M. Beato,et al.  The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus , 1983, Nature.

[182]  K. Yamamoto,et al.  DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo , 1983, Cell.

[183]  H. Weintraub,et al.  Temporal order of chromatin structural changes associated with activation of the major chicken vitellogenin gene , 1983, Cell.

[184]  K. Yamamoto,et al.  Dexamethasone regulation of alpha 1-acid glycoprotein and other acute phase reactants in rat liver and hepatoma cells. , 1983, The Journal of biological chemistry.

[185]  B. Groner,et al.  Glucocorticoid receptors recognize DNA sequences in and around murine mammary tumour virus DNA. , 1982, The EMBO journal.

[186]  M. Beato,et al.  Monoclonal antibodies to the rat liver glucocorticoid receptor. , 1982, The EMBO journal.

[187]  B. Howard,et al.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells , 1982, Molecular and cellular biology.

[188]  J. Gustafsson,et al.  Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[189]  R. Palmiter,et al.  Changes in hormone responsiveness of chick oviduct during primary stimulation with estrogen. , 1980, Developmental biology.

[190]  M. Beato,et al.  The Activated Glucocorticoid Receptor of Rat Liver , 1980 .

[191]  R. Palmiter,et al.  The action of estrogen and progesterone on the expression of the transferrin gene. A comparison of the response in chick liver and oviduct. , 1978, The Journal of biological chemistry.

[192]  J. Gustafsson,et al.  Separation of the hormone- and DNA-binding sites of the hepatic glucocorticoid receptor by means of proteolysis. , 1978, The Journal of biological chemistry.

[193]  J. Gordon,et al.  Kinetics of avian vitellogenin messenger RNA induction. Comparison between primary and secondary response to estrogen. , 1977, The Journal of biological chemistry.

[194]  A. E. Sippel,et al.  mRNA complexity and egg white protein mRNA content in mature and hormone-withdrawn oviduct , 1977, Cell.

[195]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[196]  E. Jensen,et al.  A two-step mechanism for the interaction of estradiol with rat uterus. , 1968, Proceedings of the National Academy of Sciences of the United States of America.

[197]  P. Karlson,et al.  Induktion von puff-veränderungen in den speicheldrüsenchromosomen von Chironomus t̆entans durch Ecdyson , 1960 .

[198]  M. Beato,et al.  DNA rotational positioning in a regulatory nucleosome is determined by base sequence. An algorithm to model the preferred superhelix. , 1990, Nucleic acids research.

[199]  P. Chambon,et al.  Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor , 1987, Nature.

[200]  K. Yamamoto,et al.  Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement , 1987, Nature.

[201]  B. Gloss,et al.  In vivo protein–DNA interactions in a glucocorticoid response element require the presence of the hormone , 1986, Nature.

[202]  R. Evans,et al.  Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product , 1985, Nature.

[203]  K. Yamamoto,et al.  Steroid receptor regulated transcription of specific genes and gene networks. , 1985, Annual review of genetics.

[204]  M. Beato,et al.  Regulation of the Expression of the Uteroglobin Gene by Ovarian Hormones , 1983 .

[205]  J. Taylor,et al.  Induction of the acute-phase reactant, alpha 1-acid glycoprotein, by glucocorticoids in rat hepatoma cells. , 1983, DNA.