Design, synthesis and biological evaluation of (E)-3-(3,4,5-trimethoxyphenyl) acrylic acid (TMCA) amide derivatives as anticonvulsant and sedative agents

[1]  S. Wakode,et al.  Design, synthesis and evaluation of newer 5,6-dihydropyrimidine-2(1H)-thiones as GABA-AT inhibitors for anticonvulsant potential. , 2017, Bioorganic chemistry.

[2]  A. Waszkielewicz,et al.  Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3. , 2017, Bioorganic & medicinal chemistry.

[3]  A. Kamal,et al.  Synthesis and biological evaluation of arylcinnamide linked combretastatin-A4 hybrids as tubulin polymerization inhibitors and apoptosis inducing agents. , 2016, Bioorganic & medicinal chemistry letters.

[4]  Chang-Rui Chen,et al.  3,4,5-Trimethoxycinnamic acid, one of the constituents of Polygalae Radix exerts anti-seizure effects by modulating GABAAergic systems in mice. , 2016, Journal of pharmacological sciences.

[5]  A. Waszkielewicz,et al.  Cinnamamide Derivatives for Central and Peripheral Nervous System Disorders—A Review of Structure–Activity Relationships , 2015, ChemMedChem.

[6]  J. Jun,et al.  Synthesis and biological evaluation of piperlongumine derivatives as potent anti-inflammatory agents. , 2014, Bioorganic & medicinal chemistry letters.

[7]  R. Guedes,et al.  3-Hydroxypyrrolidine and (3,4)-dihydroxypyrrolidine derivatives: inhibition of rat intestinal α-glucosidase. , 2014, Bioorganic chemistry.

[8]  Y. Kuang,et al.  Anticonvulsant and sedative effects of paederosidic acid isolated from Paederia scandens (Lour.) Merrill. in mice and rats , 2013, Pharmacology Biochemistry and Behavior.

[9]  Wen Li,et al.  Piperine exerts anti-seizure effects via the TRPV1 receptor in mice. , 2013, European journal of pharmacology.

[10]  J. Hong,et al.  3,4,5-Trimethoxycinnamic acid (TMCA), one of the constituents of Polygalae Radix enhances pentobarbital-induced sleeping behaviors via GABAAergic systems in mice , 2013, Archives of pharmacal research.

[11]  Seikwan Oh,et al.  Synthesis and Evaluation of a Series of 3,4,5‐Trimethoxycinnamic Acid Derivatives as Potential Antinarcotic Agents , 2013, Chemical biology & drug design.

[12]  F. Scorza,et al.  Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms , 2013, Pharmacology Biochemistry and Behavior.

[13]  C. Xue,et al.  Chinese herbs for memory disorders: a review and systematic analysis of classical herbal literature. , 2013, Journal of acupuncture and meridian studies.

[14]  Werner J Geldenhuys,et al.  Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease. , 2012, Bioorganic & medicinal chemistry letters.

[15]  Mahfoozur Rahman,et al.  Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats. , 2012, Journal of ethnopharmacology.

[16]  V. Cechinel Filho,et al.  A pharmacognostic approach to the Polygala genus: phytochemical and pharmacological aspects. , 2012, Chemistry & biodiversity.

[17]  V. C. Filho,et al.  A Pharmacognostic Approach to the Polygala Genus: Phytochemical and Pharmacological Aspects , 2012, Chemistry & biodiversity.

[18]  Yuan Zhang,et al.  Trial of antiepilepsirine (AES) in children with epilepsy , 1999, Brain and Development.

[19]  J. Poupaert,et al.  Anticonvulsant activity and interactions with neuronal voltage-dependent sodium channel of analogues of ameltolide. , 1998, Journal of medicinal chemistry.

[20]  Isa,et al.  Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives , 1998, Journal of medicinal chemistry.

[21]  Yasuhiro Suzuki,et al.  Antiepileptic effect of antiepilepsirine in pentylenetetrazol and amygdala kindled rats , 1993, Epilepsy Research.

[22]  S. Naik,et al.  Effect of piperine on pentobarbitone induced hypnosis in rats. , 1990, Indian journal of experimental biology.

[23]  E. A. Swinyard.  Laboratory Evaluation of Antiepileptic Drugs , 1969 .

[24]  E. A. Swinyard.  Laboratory evaluation of antiepileptic drugs. Review of laboratory methods. , 1969, Epilepsia.

[25]  T. Miya,et al.  The pharmacological activity of a series of basic esters of mono- and dialkylmalonic acids. , 1957, Journal of the American Pharmaceutical Association. American Pharmaceutical Association.