A new carotenoid glycoside from Rehmannia glutinosa

A new carotenoid glycoside, namely neo-rehmannioside (1), together with five known compounds, 6-O-seco-hydroxyaeginetoyl ajugol (2), oxyrehmaionoside B (3), ajugol (4), geniposidic acid (5) and geniposide (6) was isolated from the 95% ethanol extract of dry roots of Rehmannia glutinosa. The structure of the new compound (1) was determined based on MS, IR, 1-D and 2-D NMR spectral data.

[1]  B. G. de los Reyes,et al.  The activities of antioxidant enzymes in response to oxidative stresses and hormones in paraquat-tolerant Rehmannia glutinosa plants. , 2004, Journal of biochemistry and molecular biology.

[2]  H. Ryoo,et al.  Effect of Rehmannia glutinosa Libosch extracts on bone metabolism. , 2003, Clinica chimica acta; international journal of clinical chemistry.

[3]  C. An,et al.  Rehmannia glutinosa inhibits tumour necrosis factor-alpha and interleukin-1 secretion from mouse astrocytes. , 1999, Pharmacological research.

[4]  H. Kim,et al.  Effect of Rehmannia glutinosa on immediate type allergic reaction. , 1998, International journal of immunopharmacology.

[5]  I. Kitagawa,et al.  Absolute configurations of rehmaionosides A, B, and C and rehmapicroside three new ionone glucosides and a new monoterpene glucoside from rehmanniae radix , 1986 .

[6]  R. Oshima,et al.  DETERMINATION OF CONFIGURATION OF MONOSACCHARIDES BY HPLC ON DIASTEREOISOMERIC 1-DEOXY-1-(N-ACETYL-α-METHYLBENZYLAMINO)ALDITOL ACETATES , 1981 .

[7]  Yongxiang Zhang,et al.  Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. , 2004, Journal of ethnopharmacology.

[8]  T. Morota,et al.  Norcarotenoids of Rehmannia glutinosa var. Hueichingensis , 1991 .

[9]  T. Morota,et al.  Norcarotenoid glycosides of Rehmannia glutinosa var. Purpurea , 1991 .

[10]  T. Morota,et al.  Two non-glycosidic iridoids from Rehmannia glutinosa , 1990 .

[11]  T. Morota,et al.  Two iridoid glycosides from Rehmannia glutinosa , 1989 .

[12]  T. Morota,et al.  Five cyclopentanoid monoterpenes from Rehmannia glutinosa , 1989 .

[13]  H. Sasaki,et al.  Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. Purpurea , 1989 .