Predicting Clinical Efficacy of Photoangiolytic and Cutting/Ablating Lasers using the Chick Chorioallantoic Membrane Model: Implications for Endoscopic Voice Surgery

Objectives/Hypothesis: The optimal balance between a laser's clinical efficacy and collateral thermal damage is the major determinant for selection of a particular laser in endolaryngeal surgery. The chick chorioallantoic membrane (CAM) simulates the microvasculature of the human vocal fold and is, therefore, useful for testing effects of laser settings, mode of delivery, active cooling, and wavelength. Such information is essential for optimizing the effectiveness of lasers in treating laryngeal pathology while preserving vocal function.

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