High expression of LipL21 protein of Iranian Leptospira interrogans in E. coli, applicable for diagnostic ELISA

Leptospirosis is an emerging infectious zoonotic disease caused by pathogenic Leptospira. The disease is more prevalent among farmers in hot and humid areas of Iran. Lack of clear clinical signs have impeded the diagnosis of leptospirosis. In this study

[1]  K. Sumathi,et al.  Protective immunity of recombinant LipL21 and I-LipL21 against Leptospira interrogans serovar Autumnalis N2 infection. , 2018, Journal of infection in developing countries.

[2]  F. Kremer,et al.  Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology , 2017, Front. Immunol..

[3]  M. Picardeau Virulence of the zoonotic agent of leptospirosis: still terra incognita? , 2017, Nature Reviews Microbiology.

[4]  B. Adler,et al.  Leptospira and Leptospirosis , 2001, Current Topics in Microbiology and Immunology.

[5]  S. M. Bidhendi,et al.  Molecular detection of pathogenic leptospiral serovars by PCR, based on lipL21 gene , 2015 .

[6]  S. M. Bidhendi,et al.  APPLICATION OF MICRO AGGLUTINATION TEST IN DETECTING SEROVARS OF LEPTOSPIRA , 2014 .

[7]  R. Mirnejad,et al.  Epidemiological patterns of Leptospira spp. among slaughterhouse workers in Zanjan– Iran , 2012 .

[8]  D. Haake,et al.  Leptospira: a spirochaete with a hybrid outer membrane , 2010, Molecular microbiology.

[9]  G. Abdollahpour,et al.  SERODIAGNOSIS OF LEPTOSPIROSIS IN CATTLE IN NORTH OF IRAN, GILAN , 2009 .

[10]  N. D. Djadid,et al.  A simple and rapid nested polymerase chain reaction-restriction fragment length polymorphism technique for differentiation of pathogenic and nonpathogenic Leptospira spp. , 2009, Diagnostic microbiology and infectious disease.

[11]  H. Honarmand,et al.  ISOLATION AND SEROTYPING OF ENDEMIC LEPTOSPIRES OF EASTERN PART OF FLAT AREA OF GUILAN PROVINCE, IRAN , 2009 .

[12]  S. Asuthkar,et al.  Expression and Characterization of an Iron-Regulated Hemin-Binding Protein, HbpA, from Leptospira interrogans Serovar Lai , 2007, Infection and Immunity.

[13]  J. Leake,et al.  Acute pancreatitis in fatal anicteric leptospirosis. , 2007, The American journal of tropical medicine and hygiene.

[14]  A. Berlioz-Arthaud,et al.  [Human leptospirosis in French Polynesia. Epidemiological, clinical and bacteriological features]. , 2007, Medecine tropicale : revue du Corps de sante colonial.

[15]  M. Mahdavi,et al.  Seroepidemiological study of leptospirosis in Ghaemshahr Mazandaran province-Iran, Sept-Oct 2004 , 2006 .

[16]  A. Seguro,et al.  Leptospirosis-induced meningitis and acute renal failure in a 19-month-old male child. , 2006, Journal of medical microbiology.

[17]  A. Ko,et al.  Surfaceome of Leptospira spp , 2005, Infection and Immunity.

[18]  V. Martin,et al.  Prevention of renal infection and urinary shedding in dogs by a Leptospira vaccination. , 2005, Veterinary microbiology.

[19]  M. Fishbein,et al.  Changes in Lipopolysaccharide O Antigen Distinguish Acute versus Chronic Leptospira interrogans Infections , 2005, Infection and Immunity.

[20]  M. Willig,et al.  Leptospirosis: a zoonotic disease of global importance. , 2003, The Lancet. Infectious diseases.

[21]  J. Sejvar,et al.  Leptospirosis in “Eco-Challenge” Athletes, Malaysian Borneo, 2000 , 2003, Emerging infectious diseases.

[22]  R. Zuerner,et al.  LipL21 Is a Novel Surface-Exposed Lipoprotein of Pathogenic Leptospira Species , 2003, Infection and Immunity.

[23]  I. Christova,et al.  Human leptospirosis in Bulgaria, 1989-2001: epidemiological, clinical, and serological features. , 2003, Scandinavian journal of infectious diseases.

[24]  S. Cordwell,et al.  Global Analysis of Outer Membrane Proteins from Leptospira interrogans Serovar Lai , 2002, Infection and Immunity.

[25]  Christovam Barcellos,et al.  The place behind the case: leptospirosis risks and associated environmental conditions in a flood-related outbreak in Rio de Janeiro. , 2001, Cadernos de saude publica.

[26]  J. Vandyousefi,et al.  A SEROLOGICAL SURVEY ON BOVINE LEPTOSPIROSIS IN SHIRAZ, IRAN , 2000 .

[27]  L. Guigand,et al.  Chronic hepatitis associated with leptospiral infection in vaccinated beagles. , 1997, Journal of comparative pathology.

[28]  R. Figueroa Barrios [Chronic hepatitis]. , 1995, Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru.

[29]  S. Faine Guidelines for the control of leptospirosis. , 1982, WHO offset publication.

[30]  J. Kathe [Leptospirosis as an occupational disease]. , 1959, Archiv fur Gewerbepathologie und Gewerbehygiene.

[31]  C. Cox Human leptospirosis. , 1955, The South Dakota journal of medicine and pharmacy.