Knockdown of EWSR1/FLI1 expression alters the transcriptome of Ewing sarcoma cells in vitro

[1]  Guo-Ping Zhou,et al.  Analysis of differentially expressed genes based on microarray data of glioma. , 2015, International journal of clinical and experimental medicine.

[2]  Mark Girolami,et al.  EWS-FLI1 employs an E2F switch to drive target gene expression , 2015, Nucleic acids research.

[3]  Zhen Liu,et al.  Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis , 2015, Journal of experimental & clinical cancer research : CR.

[4]  R. Skotheim,et al.  TIN: An R Package for Transcriptome Instability Analysis , 2015, Cancer informatics.

[5]  Jihan Wang,et al.  Altered Expression of Hypoxia-Inducible Factor-1α (HIF-1α) and Its Regulatory Genes in Gastric Cancer Tissues , 2014, PloS one.

[6]  Allen R. Chen,et al.  WT1 regulates angiogenesis in Ewing Sarcoma , 2014, Oncotarget.

[7]  Min Li,et al.  Research on the Typical miRNA and Target Genes in Squamous Cell Carcinoma and Adenocarcinoma of Esophagus Cancer with DNA Microarray , 2014, Pathology & Oncology Research.

[8]  P. Meltzer,et al.  Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer , 2013, Genome research.

[9]  L. Embree,et al.  Ewing sarcoma fusion protein EWSR1/FLI1 interacts with EWSR1 leading to mitotic defects in zebrafish embryos and human cell lines. , 2009, Cancer research.

[10]  O. Delattre,et al.  Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer , 2008, Proceedings of the National Academy of Sciences.

[11]  John Anderson,et al.  B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: implications for cell survival. , 2007, Blood cells, molecules & diseases.

[12]  Michael Q. Zhang,et al.  TRED: a transcriptional regulatory element database, new entries and other development , 2007, Nucleic Acids Res..

[13]  S. Lessnick,et al.  Identification of Target Genes in Their Native Cellular Context , 2006, Cell cycle.

[14]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[15]  T. Golub,et al.  Supplemental Information for , 2002 .

[16]  Olivier Delattre,et al.  EWS, but Not EWS-FLI-1, Is Associated with Both TFIID and RNA Polymerase II: Interactions between Two Members of the TET Family, EWS and hTAFII68, and Subunits of TFIID and RNA Polymerase II Complexes , 1998, Molecular and Cellular Biology.

[17]  Marcienne M Wright,et al.  EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic , 1997, Nature Genetics.

[18]  P. Chambon,et al.  hTAF(II)68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. , 1996, The EMBO journal.

[19]  C. Denny,et al.  A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. , 1995, Oncogene.

[20]  C. Denny,et al.  Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene. , 1995, Oncogene.

[21]  P. Sorensen,et al.  A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG , 1994, Nature Genetics.

[22]  E. Reddy,et al.  Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein. , 1993, Oncogene.

[23]  C. Denny,et al.  Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[24]  G. Thomas,et al.  Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours , 1992, Nature.