Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus

[1]  Asla Pitkänen,et al.  Molecular and cellular basis of epileptogenesis in symptomatic epilepsy , 2009, Epilepsy & Behavior.

[2]  R. Vincentelli,et al.  Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR. , 2008, Human molecular genetics.

[3]  Aamir Ahmad,et al.  Evolving role of uPA/uPAR system in human cancers. , 2008, Cancer treatment reviews.

[4]  L. Kaczmarek,et al.  Important role of matrix metalloproteinase 9 in epileptogenesis , 2008, The Journal of cell biology.

[5]  N. Nagai,et al.  Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke , 2008, Neuroscience Letters.

[6]  S. Lorenzl,et al.  A role for the urokinase-type plasminogen activator system in amyotrophic lateral sclerosis , 2007, Experimental Neurology.

[7]  F. D. da Silva,et al.  Dynamic Changes of Proteases and Protease Inhibitors Revealed by Microarray Analysis in CA3 and Entorhinal Cortex during Epileptogenesis in the Rat , 2007, Epilepsia.

[8]  H. Kumamoto,et al.  Immunohistochemical detection of uPA, uPAR, PAI-1, and maspin in ameloblastic tumors. , 2007, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[9]  Philippe Coubes,et al.  Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. , 2007, Brain : a journal of neurology.

[10]  A. Erisir,et al.  Selective loss of dentate hilar interneurons contributes to reduced synaptic inhibition of granule cells in an electrical stimulation‐based animal model of temporal lobe epilepsy , 2007, The Journal of comparative neurology.

[11]  A. Pitkänen,et al.  Increased expression and activity of urokinase‐type plasminogen activator during epileptogenesis , 2006, The European journal of neuroscience.

[12]  D. Graham,et al.  Impaired fibrinolysis and traumatic brain injury in mice. , 2006, Journal of neurotrauma.

[13]  M. West,et al.  Electroconvulsive Seizures Induce Angiogenesis in Adult Rat Hippocampus , 2005, Biological Psychiatry.

[14]  Pat Levitt,et al.  Disruption of Interneuron Development , 2005, Epilepsia.

[15]  P. Levitt,et al.  Region‐ and age‐specific deficits in γ‐aminobutyric acidergic neuron development in the telencephalon of the uPAR–/– mouse , 2005, The Journal of comparative neurology.

[16]  M. Cuzner,et al.  A role for the plasminogen activator system in inflammation and neurodegeneration in the central nervous system during experimental allergic encephalomyelitis. , 2005, The American journal of pathology.

[17]  M. Caputi,et al.  The urokinase plasminogen activator and its receptor , 2005, Thrombosis and Haemostasis.

[18]  G. Rossi,et al.  Soluble and cleaved forms of the urokinase-receptor: degradation products or active molecules? , 2005, Thrombosis and Haemostasis.

[19]  Tiina Wahlfors,et al.  Cancer cells as targets for lentivirus-mediated gene transfer and gene therapy. , 2004, International journal of oncology.

[20]  P. Dash,et al.  A Molecular Description of Brain Trauma Pathophysiology Using Microarray Technology: An Overview , 2004, Neurochemical Research.

[21]  W. Schneider,et al.  LR11, an LDL Receptor Gene Family Member, Is a Novel Regulator of Smooth Muscle Cell Migration , 2004, Circulation research.

[22]  R. Farias-Eisner,et al.  Searching for Depolarization-Induced Genes that Modulate Synaptic Plasticity and Neurotrophin-Induced Genes that Mediate Neuronal Differentiation , 2000, Neurochemical Research.

[23]  Walter E. Laug,et al.  Urokinase induces receptor mediated brain tumor cell migration and invasion , 1998, Journal of Neuro-Oncology.

[24]  G. Lynch,et al.  Integrins, synaptic plasticity and epileptogenesis. , 2004, Advances in experimental medicine and biology.

[25]  V. Tkachuk,et al.  Plasminogen Activators in Vascular Remodeling and Angiogenesis , 2004, Biochemistry (Moscow).

[26]  H. Scharfman,et al.  Vascular endothelial growth factor (VEGF) in seizures: a double-edged sword. , 2004, Advances in experimental medicine and biology.

[27]  R G Sola,et al.  Histopathology and reorganization of chandelier cells in the human epileptic sclerotic hippocampus. , 2004, Brain : a journal of neurology.

[28]  E. Tremoli,et al.  Endogenous proteolytic activity in a rat model of spontaneous cerebral stroke , 2003, Brain Research.

[29]  D. Waisman,et al.  Exploitation of Astrocytes by Glioma Cells to Facilitate Invasiveness: A Mechanism Involving Matrix Metalloproteinase-2 and the Urokinase-Type Plasminogen Activator–Plasmin Cascade , 2003, The Journal of Neuroscience.

[30]  M. Frotscher,et al.  “Dormant basket cell” hypothesis revisited: Relative vulnerabilities of dentate gyrus mossy cells and inhibitory interneurons after hippocampal status epilepticus in the rat , 2003, The Journal of comparative neurology.

[31]  J. Rakic,et al.  Role of plasminogen activator-plasmin system in tumor angiogenesis , 2003, Cellular and Molecular Life Sciences CMLS.

[32]  K. Lukowiak,et al.  Generation of Functional Inhibitory Neurons in the Adult Rat Hippocampus , 2003, The Journal of Neuroscience.

[33]  Caleb F. Davis,et al.  Genetic Disruption of Cortical Interneuron Development Causes Region- and GABA Cell Type-Specific Deficits, Epilepsy, and Behavioral Dysfunction , 2003, The Journal of Neuroscience.

[34]  A. Pitkänen,et al.  cDNA profiling of epileptogenesis in the rat brain , 2003, The European journal of neuroscience.

[35]  P. Carmeliet,et al.  uPAR: a versatile signalling orchestrator , 2002, Nature Reviews Molecular Cell Biology.

[36]  S. Estus,et al.  Urokinase‐type plasminogen activator inhibits amyloid‐β neurotoxicity and fibrillogenesis via plasminogen , 2002, Journal of neuroscience research.

[37]  E. Lo,et al.  Extracellular proteolysis in brain injury and inflammation: Role for plasminogen activators and matrix metalloproteinases , 2002, Journal of neuroscience research.

[38]  T. Luther,et al.  Cortical neurons of Creutzfeldt–Jakob disease patients express the urokinase-type plasminogen activator receptor , 2002, Neuroscience Letters.

[39]  P. Vaupel,et al.  Expression pattern of the urokinase-plasminogen activator system in rat DS-sarcoma: Role of oxygenation status and tumour size , 2002, British Journal of Cancer.

[40]  L. Lue,et al.  Increased expression of the urokinase plasminogen-activator receptor in amyloid β peptide-treated human brain microglia and in AD brains , 2002, Brain Research.

[41]  J. Newcombe,et al.  Plasminogen activators in multiple sclerosis lesions: implications for the inflammatory response and axonal damage. , 2001, Brain : a journal of neurology.

[42]  M. Pepper Role of the Matrix Metalloproteinase and Plasminogen Activator-Plasmin Systems in Angiogenesis , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[43]  N. Seeds,et al.  Induction of the Plasminogen Activator System Accompanies Peripheral Nerve Regeneration after Sciatic Nerve Crush , 2001, The Journal of Neuroscience.

[44]  J. Koziol,et al.  Rapid Differential Endogenous Plasminogen Activator Expression After Acute Middle Cerebral Artery Occlusion , 2001, Stroke.

[45]  S. Reddy,et al.  Expression of the urokinase plasminogen activator receptor is transiently required during “priming” of PC12 cells in nerve growth factor‐directed cellular differentiation , 2001, Journal of neuroscience research.

[46]  P. Carmeliet,et al.  Roles of urokinase type plasminogen activator in a brain stab wound , 2000, Brain Research.

[47]  J. Schwab,et al.  Lesion‐associated accumulation of uPAR/CD87‐ expressing infiltrating granulocytes, activated microglial cells/macrophages and upregulation by endothelial cells following TBI and FCI in humans , 2000, Neuropathology and applied neurobiology.

[48]  S. Traynelis,et al.  Serine proteases and brain damage – is there a link? , 2000, Trends in Neurosciences.

[49]  H. Scharfman,et al.  Granule-Like Neurons at the Hilar/CA3 Border after Status Epilepticus and Their Synchrony with Area CA3 Pyramidal Cells: Functional Implications of Seizure-Induced Neurogenesis , 2000, The Journal of Neuroscience.

[50]  S. Scheff,et al.  The Plasmin System Is Induced by and Degrades Amyloid-β Aggregates , 2000, The Journal of Neuroscience.

[51]  S. Yoshimura,et al.  Elevation of mRNA levels of tissue-type plasminogen activator and urokinase-type plasminogen activator in hippocampus and cerebral cortex following middle cerebral artery occlusion in rats , 2000, Neurological research.

[52]  C E Elger,et al.  Loss of Hilar Mossy Cells in Ammon's Horn Sclerosis , 2000, Epilepsia.

[53]  Asla Pitkänen,et al.  A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat , 2000, Epilepsy Research.

[54]  R. Farias-Eisner,et al.  The Urokinase Plasminogen Activator Receptor (UPAR) Is Preferentially Induced by Nerve Growth Factor in PC12 Pheochromocytoma Cells and Is Required for NGF-Driven Differentiation , 2000, The Journal of Neuroscience.

[55]  S. Scheff,et al.  The Plasmin System Is Induced by and Degrades Amyloid-b Aggregates , 2000 .

[56]  M. R. Bigio,et al.  Localization of urokinase-type plasminogen activator, its receptor, and inhibitors in mouse forebrain during postnatal development , 1999, International Journal of Developmental Neuroscience.

[57]  M. Chopp,et al.  The effect of age on expression of endogenous plasminogen activators after focal cerebral ischemia in mice , 1999, Brain Research.

[58]  E. Appella,et al.  A urokinase‐sensitive region of the human urokinase receptor is responsible for its chemotactic activity , 1997, The EMBO journal.

[59]  L. Houenou,et al.  The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system , 1997, Brain Research Reviews.

[60]  P. Dell’Era,et al.  Urokinase-type plasminogen activator overexpression enhances the invasive capacity of endothelial cells. , 1997, Microvascular research.

[61]  G. Buzsáki,et al.  Interneurons of the hippocampus , 1998, Hippocampus.

[62]  J. Antel,et al.  Expression of the activation marker urokinase plasminogen‐activator receptor in cultured human central nervous system microglia , 1996, Journal of neuroscience research.

[63]  Gary A. Rosenberg,et al.  Proteolytic Cascade Enzymes Increase in Focal Cerebral Ischemia in Rat , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[64]  N. Seeds,et al.  Modulated expression of plasminogen activator system components in cultured cells from dissociated mouse dorsal root ganglia , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[65]  M. Olman,et al.  Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma. , 1995, The American journal of pathology.

[66]  Julio Cesar Sampaio P. Leite,et al.  Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[67]  S. Mandriota,et al.  Vascular Endothelial Growth Factor Increases Urokinase Receptor Expression in Vascular Endothelial Cells (*) , 1995, The Journal of Biological Chemistry.

[68]  J. Bruner,et al.  Expression and localization of urokinase-type plasminogen activator receptor in human gliomas. , 1994, Cancer research.

[69]  J. Bruner,et al.  Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo. , 1994, Cancer research.

[70]  F. Dudek,et al.  Functional significance of hippocampal plasticity in epileptic brain: Electrophysiological changes of the dentate granule cells associated with mossy fiber sprouting , 1994, Hippocampus.

[71]  Y. Dudai,et al.  Overexpression of urokinase-type plasminogen activator in transgenic mice is correlated with impaired learning. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[72]  M. A. Dent,et al.  Urokinase‐type Plasminogen Activator Expression by Neurons and Oligodendrocytes During Process Outgrowth in Developing Rat Brain , 1993, The European journal of neuroscience.

[73]  D. Owen,et al.  The expression of tissue and urokinase-type plasminogen activators in neural development suggests different modes of proteolytic involvement in neuronal growth. , 1992, Development.

[74]  H. Buettner,et al.  Neuronal plasminogen activators: cell surface binding sites and involvement in neurite outgrowth , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[75]  G. Cascino,et al.  Mossy fiber synaptic reorganization in the epileptic human temporal lobe , 1989, Annals of neurology.

[76]  M J Campbell,et al.  An immunohistochemical characterization of somatostatin‐28 and somatostatin‐281–12 in monkey prefrontal cortex , 1986, The Journal of comparative neurology.

[77]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[78]  J. P. Irigoyena,et al.  The plasminogen activator system : biology and regulation , 2022 .