Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring

[1]  Jan Nedergaard,et al.  Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study , 2017, Molecular metabolism.

[2]  W. Reik,et al.  Comparative Principles of DNA Methylation Reprogramming during Human and Mouse In Vitro Primordial Germ Cell Specification , 2016, Developmental cell.

[3]  J. Speakman,et al.  Type 2 diabetes, but not obesity, prevalence is positively associated with ambient temperature , 2016, Scientific Reports.

[4]  O. Rando.  Intergenerational Transfer of Epigenetic Information in Sperm. , 2016, Cold Spring Harbor perspectives in medicine.

[5]  I. Burger,et al.  Anatomical Grading for Metabolic Activity of Brown Adipose Tissue , 2016, PloS one.

[6]  H. Shulha,et al.  Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome. , 2015, Developmental cell.

[7]  Kyungdo Han,et al.  Ambient Temperature and Prevalence of Obesity: A Nationwide Population-Based Study in Korea , 2015, PloS one.

[8]  B. Spiegelman,et al.  A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat , 2015, Cell.

[9]  P. Arner,et al.  Cidea improves the metabolic profile through expansion of adipose tissue , 2015, Nature Communications.

[10]  Zhengming Chen,et al.  The Associations of Month of Birth With Body Mass Index, Waist Circumference, and Leg Length: Findings From the China Kadoorie Biobank of 0.5 Million Adults , 2015, Journal of epidemiology.

[11]  S. Trauger,et al.  Activation of human brown adipose tissue by a β3-adrenergic receptor agonist. , 2015, Cell metabolism.

[12]  P. Itskov,et al.  Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity , 2014, Cell.

[13]  F. Soriguer,et al.  Ambient temperature and prevalence of obesity in the Spanish population: The Di@bet.es study , 2014, Obesity.

[14]  Gangning Liang,et al.  Gene body methylation can alter gene expression and is a therapeutic target in cancer. , 2014, Cancer cell.

[15]  K. Sales,et al.  Seminal plasma induces the expression of IL-1α in normal and neoplastic cervical cells via EP2/EGFR/PI3K/AKT pathway , 2014, Journal of molecular signaling.

[16]  D. Guertin,et al.  Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed , 2014, Nature Communications.

[17]  Bruce M. Spiegelman,et al.  What We Talk About When We Talk About Fat , 2014, Cell.

[18]  C. Maloney,et al.  Paternal high‐fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  N. Petrovic,et al.  UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic. , 2013, Cell reports.

[20]  C. Wolfrum,et al.  The origin and definition of brite versus white and classical brown adipocytes , 2013, Adipocyte.

[21]  T. Iwanaga,et al.  Recruited brown adipose tissue as an antiobesity agent in humans. , 2013, The Journal of clinical investigation.

[22]  U. Eriksson,et al.  Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease , 2013, Nature Protocols.

[23]  T. Rülicke,et al.  Bi-directional interconversion of brite and white adipocytes , 2013, Nature Cell Biology.

[24]  Peter A. Jones.  Functions of DNA methylation: islands, start sites, gene bodies and beyond , 2012, Nature Reviews Genetics.

[25]  F. Villarroya,et al.  BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions , 2012, Cell.

[26]  E. Greer,et al.  Histone methylation: a dynamic mark in health, disease and inheritance , 2012, Nature Reviews Genetics.

[27]  E. Whitelaw,et al.  Understanding transgenerational epigenetic inheritance via the gametes in mammals , 2012, Nature Reviews Genetics.

[28]  D. Gašperíková,et al.  Adipogenesis and insulin sensitivity in obesity are regulated by retinoid-related orphan receptor gamma , 2011, EMBO molecular medicine.

[29]  Ryoichi Nakamura,et al.  Inheritance of Stress-Induced, ATF-2-Dependent Epigenetic Change , 2011, Cell.

[30]  S. Andrews,et al.  Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications , 2011, Bioinform..

[31]  F. Villarroya,et al.  Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue* , 2011, The Journal of Biological Chemistry.

[32]  Oliver T. Bruns,et al.  Brown adipose tissue activity controls triglyceride clearance , 2011, Nature Medicine.

[33]  Zhiping Weng,et al.  Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals , 2010, Cell.

[34]  Margaret J. Morris,et al.  Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring , 2010, Nature.

[35]  Y. Tseng,et al.  Cellular bioenergetics as a target for obesity therapy , 2010, Nature Reviews Drug Discovery.

[36]  S. Cinti,et al.  Distribution and development of brown adipocytes in the murine and human adipose organ. , 2010, Cell metabolism.

[37]  Antoine H. F. M. Peters,et al.  Genetic vasectomy—Overexpression of Prm1‐EGFP fusion protein in elongating spermatids causes dominant male sterility in mice , 2010, Genesis.

[38]  J. Orava,et al.  Functional brown adipose tissue in healthy adults. , 2009, The New England journal of medicine.

[39]  W. D. van Marken Lichtenbelt,et al.  Cold-activated brown adipose tissue in healthy men. , 2009, The New England journal of medicine.

[40]  J. Peychl,et al.  Live Cell Multicolor Imaging of Lipid Droplets with a New Dye, LD540 , 2009, Traffic.

[41]  Jan Nedergaard,et al.  The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[42]  Michael E. Symonds,et al.  Brown Adipose Tissue and Seasonal Variation in Humans , 2009, Diabetes.

[43]  M. Miyagawa,et al.  High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans , 2009, Diabetes.

[44]  E. Palmer,et al.  Identification and importance of brown adipose tissue in adult humans. , 2009, The New England journal of medicine.

[45]  T. Bengtsson,et al.  Unexpected evidence for active brown adipose tissue in adult humans. , 2007, American journal of physiology. Endocrinology and metabolism.

[46]  Gary King,et al.  Matching as Nonparametric Preprocessing for Reducing Model Dependence in Parametric Causal Inference , 2007, Political Analysis.

[47]  W. Alvord,et al.  Preconceptional fasting of fathers alters serum glucose in offspring of mice. , 2006, Nutrition.

[48]  A. Afonso.  Immigration and Its Impacts in Switzerland , 2004 .

[49]  M. Renfree,et al.  Functional analysis of the cooled rat testis. , 2004, Journal of andrology.

[50]  J. Feldon,et al.  Comparison of the effects of early handling and early deprivation on conditioned stimulus, context, and spatial learning and memory in adult rats. , 2003, Behavioral neuroscience.

[51]  A. Bird,et al.  Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.

[52]  A. Buck,et al.  Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region , 2002, European Journal of Nuclear Medicine and Molecular Imaging.

[53]  J. Houštěk,et al.  Beta-adrenergic, cAMP-mediated stimulation of proliferation of brown fat cells in primary culture. Mediation via beta 1 but not via beta 3 adrenoceptors. , 1992, The Journal of biological chemistry.

[54]  J. Heeren,et al.  Adipose tissue browning and metabolic health , 2014, Nature Reviews Endocrinology.

[55]  Jan Nedergaard,et al.  Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.

[56]  The Wenner-Gren Institute,et al.  Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.

[57]  D. Phillips,et al.  Birth weight, climate at birth and the risk of obesity in adult life , 2000, International Journal of Obesity.

[58]  Matthew H. Kaufman,et al.  The Atlas of Mouse Development , 1992 .