Immunosuppressive therapy in Wegener's granulomatosis.

Abstract. The case history of a 26-year-old woman with Wegener's granulomatosis is presented. There were clinical signs of cutaneous, pulmonary, mastoidal and renal involvements. During an oliguric period of five weeks life was maintained by peritoneal dialysis. Eventually she responded favourably to combined treatment with azathioprine and corticosteroids. During one year's follow-up the serum creatinine level has remained unchanged at about 2 mg/100 ml. There has also been a marked improvement of the other manifestations of the disease, and her general condition is good.