Integrative approach identifies corticosteroid response variant in diverse populations with asthma

[1]  Wei Gao,et al.  Key findings , 2019, No School Left Behind.

[2]  S. Mirarab,et al.  Sequence Analysis , 2020, Encyclopedia of Bioinformatics and Computational Biology.

[3]  Alan M. Kwong,et al.  Next-generation genotype imputation service and methods , 2016, Nature Genetics.

[4]  E. Burchard,et al.  Assessing differences in inhaled corticosteroid response by self-reported race-ethnicity and genetic ancestry among asthmatic subjects. , 2016, The Journal of allergy and clinical immunology.

[5]  D. Endo,et al.  Serum eosinophil-derived neurotoxin: correlation with persistent airflow limitation in adults with house-dust mite allergic asthma. , 2015, Allergy and asthma proceedings.

[6]  Mike Thomas,et al.  Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study. , 2015, The Lancet. Respiratory medicine.

[7]  Terrie E. Kitchner,et al.  CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids , 2015, Immunity, inflammation and disease.

[8]  D. Postma,et al.  ST13 polymorphisms and their effect on exacerbations in steroid‐treated asthmatic children and young adults , 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[9]  E. Israel,et al.  Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma , 2015, The Pharmacogenomics Journal.

[10]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[11]  Weiliang Qiu,et al.  Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis. , 2014, Human molecular genetics.

[12]  M. Kubo,et al.  Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. , 2014, The Journal of allergy and clinical immunology.

[13]  M. Peters,et al.  Systematic identification of trans eQTLs as putative drivers of known disease associations , 2013, Nature Genetics.

[14]  Pedro G. Ferreira,et al.  Transcriptome and genome sequencing uncovers functional variation in humans , 2013, Nature.

[15]  Ellen T. Gelfand,et al.  The Genotype-Tissue Expression (GTEx) project , 2013, Nature Genetics.

[16]  R. Wu,et al.  Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. , 2012, American journal of respiratory and critical care medicine.

[17]  R. Severson,et al.  The relationship between combination inhaled corticosteroid and long-acting β-agonist use and severe asthma exacerbations in a diverse population. , 2012, The Journal of allergy and clinical immunology.

[18]  D. Hui,et al.  Evaluation of the asthma control test: A reliable determinant of disease stability and a predictor of future exacerbations , 2012, Respirology.

[19]  Teresa A. Webster,et al.  Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. , 2011, Genomics.

[20]  E. Burchard,et al.  Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. , 2011, The Journal of allergy and clinical immunology.

[21]  Bradley E. Chipps Genomewide Association Between GLCCI1 and Response to Glucocorticoid Therapy in Asthma , 2011, Pediatrics.

[22]  Colin N. Dewey,et al.  RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.

[23]  Francisco M. De La Vega,et al.  Genomics for the world , 2011, Nature.

[24]  Christopher R. Gignoux,et al.  Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations. , 2011, The Journal of allergy and clinical immunology.

[25]  Ryan D. Hernandez,et al.  Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations , 2011, Nature Genetics.

[26]  D. Nicolae,et al.  The Missing Association: Sequencing‐Based Discovery of Novel SNPs in VKORC1 and CYP2C9 That Affect Warfarin Dose in African Americans , 2011, Clinical pharmacology and therapeutics.

[27]  Scott T. Weiss,et al.  Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression , 2011, PLoS genetics.

[28]  E. Burchard,et al.  Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma. , 2010, The Journal of allergy and clinical immunology.

[29]  R. Fletcher,et al.  Eosinophil-Derived Neurotoxin in Childhood Asthma: Correlation With Disease Severity , 2010, The Journal of asthma : official journal of the Association for the Care of Asthma.

[30]  Ingo Ruczinski,et al.  Variants of DENND1B associated with asthma in children. , 2010, The New England journal of medicine.

[31]  E. Bleecker,et al.  The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. , 2009, The Journal of allergy and clinical immunology.

[32]  Toshiyuki Yamagata,et al.  The Strategy for Predicting Future Exacerbation of Asthma Using a Combination of the Asthma Control Test and Lung Function Test , 2009, The Journal of asthma : official journal of the Association for the Care of Asthma.

[33]  C. Rand,et al.  Patients with asthma who do not fill their inhaled corticosteroids: a study of primary nonadherence. , 2007, The Journal of allergy and clinical immunology.

[34]  I. Pavord,et al.  Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma , 2007, Thorax.

[35]  M. Kosinski,et al.  Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. , 2006, The Journal of allergy and clinical immunology.

[36]  S. Weiss,et al.  TBX21: A functional variant predicts improvement in asthma with the use of inhaled corticosteroids , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[37]  A David Paltiel,et al.  A single measure of FEV1 is associated with risk of asthma attacks in long-term follow-up. , 2004, Chest.

[38]  Christine C Johnson,et al.  Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma. , 2004, The Journal of allergy and clinical immunology.

[39]  D. Sin,et al.  Pharmacological management to reduce exacerbations in adults with asthma: a systematic review and meta-analysis. , 2004, JAMA.

[40]  S. Gabriel,et al.  Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. , 2004, Human molecular genetics.

[41]  Harold I Feldman,et al.  Modifiable barriers to adherence to inhaled steroids among adults with asthma: it's not just black and white. , 2003, The Journal of allergy and clinical immunology.

[42]  H. Kerstjens,et al.  Accuracy of eosinophils and eosinophil cationic protein to predict steroid improvement in asthma , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[43]  S. Suissa,et al.  Inhaled corticosteroids: impact on asthma morbidity and mortality. , 2001, The Journal of allergy and clinical immunology.

[44]  G. Walsh Eosinophil granule proteins and their role in disease , 2001, Current opinion in hematology.

[45]  R. Pauwels,et al.  Low-dose inhaled corticosteroids and the prevention of death from asthma. , 2000, The New England journal of medicine.

[46]  I. Pavord,et al.  Non-eosinophilic cor ticosteroid unresponsive asthma , 1999, The Lancet.

[47]  A. Niimi,et al.  Serum eosinophil cationic protein as a marker of eosinophilic inflammation in asthma , 1998, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[48]  S. Bonini,et al.  Serum levels of eosinophil cationic protein in allergic diseases and natural allergen exposure. , 1996, The Journal of allergy and clinical immunology.

[49]  Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. , 2007, The Journal of allergy and clinical immunology.

[50]  D. Snider,et al.  Asthma prevalence and control characteristics by race/ethnicity--United States, 2002. , 2004, MMWR. Morbidity and mortality weekly report.