RBC histogram: Utility in diagnosis of various anemia

Introduction: Anemia is a common health problem in overall world especially in developing countries. Early and accurate diagnosis is needed to decide correct line of treatment. Material & Methods: The study was conducted in Hematology laboratory of medical college hospital for a period of 12 month during January 2018 to December 2018. Total 1500 anemic patients of 10-70 year of age were included in the study. Interpretation of RBC Histogram and peripheral smear examination was done in each case. Results: Out of total 1500 anemic cases, microcytic anemia is most common cause followed by normocytic, Dimorphic and macrocytic anemia. Female patients are more than male patients and most common involved age group is 31-40 years followed by 21-30 years. Discussion: Interpretation of RBC histograms is useful method for initial diagnosis of anemia and can be used for screening purpose to screen large population.

[1]  Bhavana Grandhi,et al.  RBC Histogram as supplementary diagnostic tool with peripheral smear examination in evaluating anemias , 2017 .

[2]  Sandhya.,et al.  STUDY OF RBC HISTOGRAM IN VARIOUS ANEMIAS , 2014 .

[3]  I. Perry,et al.  Haematinic Deficiency and Macrocytosis in Middle-Aged and Older Adults , 2013, PloS one.

[4]  Ashutosh Kumar,et al.  An analytical study on peripheral blood smears in anemia and correlation with cell counter generated red cell parameters , 2013 .

[5]  M. Njeim,et al.  Unexplained Macrocytosis , 2013, Southern medical journal.

[6]  Benie T. Constantino,et al.  The Red Cell Histogram and The Dimorphic Red Cell Population , 2011 .

[7]  N. Kakkar,et al.  Red Cell Cytograms Generated by an ADVIA 120 Automated Hematology Analyzer: Characteristic Patterns in Common Hematological Conditions , 2009 .

[8]  J. Kaferle,et al.  Evaluation of macrocytosis. , 2009, American family physician.

[9]  B. Skudlarska,et al.  Anemia prevalence in a home visit geriatric population. , 2008, Journal of the American Medical Directors Association.

[10]  B. Hyun,et al.  The automated CBC. A current perspective. , 1994, Hematology/oncology clinics of North America.

[11]  J. Bessman Red blood cell fragmentation. Improved detection and identification of causes. , 1988, American journal of clinical pathology.

[12]  D. Sainty,et al.  New parameters in erythrocyte counting. Value of histograms. , 1987, Archives of pathology & laboratory medicine.

[13]  F. Gardner,et al.  Improved classification of anemias by MCV and RDW. , 1983, American journal of clinical pathology.