What's wrong with my mouse cage? Methodological considerations for modeling lifestyle factors and gene–environment interactions in mice

[1]  A. Hannan,et al.  Environmental factors as modulators of neurodegeneration: Insights from gene–environment interactions in Huntington's disease , 2015, Neuroscience & Biobehavioral Reviews.

[2]  J. O’Keefe,et al.  Dose of jogging and long-term mortality: the Copenhagen City Heart Study. , 2015, Journal of the American College of Cardiology.

[3]  T. Renoir,et al.  The influence of the HPG axis on stress response and depressive-like behaviour in a transgenic mouse model of Huntington's disease , 2015, Experimental Neurology.

[4]  A. Hannan,et al.  Novel ethological endophenotypes in a transgenic mouse model of Huntington's disease , 2015, Behavioural Brain Research.

[5]  A. Hannan,et al.  Effects of chronic stress on the onset and progression of Huntington's disease in transgenic mice , 2014, Neurobiology of Disease.

[6]  A. Hannan,et al.  Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice , 2014, Behavioural Brain Research.

[7]  A. Hannan,et al.  High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice , 2014, Neurobiology of Disease.

[8]  N. Wood,et al.  Beneficial effects of environmental enrichment and food entrainment in the R6/2 mouse model of Huntington's disease , 2014, Brain and behavior.

[9]  A. Morton,et al.  Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease , 2014, Neurobiology of Disease.

[10]  M. Potenza,et al.  Cumulative Adversity Sensitizes Neural Response to Acute Stress: Association with Health Symptoms , 2014, Neuropsychopharmacology.

[11]  L. Quinn,et al.  A Randomized Feasibility Study of a 12-Week Community-Based Exercise Program for People With Huntington's Disease , 2013, Journal of neurologic physical therapy : JNPT.

[12]  D. Stout,et al.  Individually ventilated cages impose cold stress on laboratory mice: a source of systemic experimental variability. , 2013, Journal of the American Association for Laboratory Animal Science : JAALAS.

[13]  G. Forster,et al.  Adolescent social defeat decreases spatial working memory performance in adulthood , 2013, Behavioral and Brain Functions.

[14]  S. Dunnett,et al.  Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model , 2013, Experimental Neurology.

[15]  M. Hayden,et al.  Choosing an animal model for the study of Huntington's disease , 2013, Nature Reviews Neuroscience.

[16]  A. Hannan,et al.  Short-term memory acquisition in female Huntington's disease mice is vulnerable to acute stress , 2013, Behavioural Brain Research.

[17]  S. Kostyk,et al.  Video game play (Dance Dance Revolution) as a potential exercise therapy in Huntington’s disease: a controlled clinical trial , 2013, Clinical rehabilitation.

[18]  A. Hannan,et al.  Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice , 2013, Molecular and Cellular Neuroscience.

[19]  J. Kingham,et al.  Behavioural consequences of IVC cages on male and female C57BL/6J mice , 2013, Neuroscience.

[20]  L. Quinn,et al.  What effect does a structured home-based exercise programme have on people with Huntington’s disease? A randomized, controlled pilot study , 2013, Clinical rehabilitation.

[21]  J. Lucas,et al.  Impact of nesting material on mouse body temperature and physiology , 2013, Physiology & Behavior.

[22]  R. S. Sloviter,et al.  Standardized Environmental Enrichment Supports Enhanced Brain Plasticity in Healthy Rats and Prevents Cognitive Impairment in Epileptic Rats , 2013, PloS one.

[23]  L. Lanfumey,et al.  Differential effects of early environmental enrichment on emotionality related behaviours in Huntington's disease transgenic mice , 2013, The Journal of physiology.

[24]  A. Morton,et al.  B29 Voluntary exercise improves circadian function in a mouse model of Huntington's disease , 2012, Journal of Neurology Neurosurgery & Psychiatry.

[25]  A. Hannan,et al.  Environmental enrichment rescues female-specific hyperactivity of the hypothalamic-pituitary-adrenal axis in a model of Huntington's disease , 2012, Translational Psychiatry.

[26]  S. Dunnett,et al.  Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice , 2012, Brain Research Bulletin.

[27]  L. Lanfumey,et al.  Treatment of depressive‐like behaviour in Huntington's disease mice by chronic sertraline and exercise , 2012, British journal of pharmacology.

[28]  F. Saudou,et al.  Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation , 2012, Neuroscience Letters.

[29]  J. Cannon,et al.  The role of environmental exposures in neurodegeneration and neurodegenerative diseases. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[30]  L. Lanfumey,et al.  Effect of enhanced voluntary physical exercise on brain levels of monoamines in Huntington disease mice , 2011, PLoS currents.

[31]  V. Bakshi,et al.  Fos expression following regimens of predator stress versus footshock that differentially affect prepulse inhibition in rats , 2011, Physiology & Behavior.

[32]  N. Wood,et al.  “Brain training” improves cognitive performance and survival in a transgenic mouse model of Huntington's disease , 2011, Neurobiology of Disease.

[33]  H. van Praag,et al.  Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington’s disease , 2010, PLoS currents.

[34]  Y. Sztainberg,et al.  An environmental enrichment model for mice , 2010, Nature Protocols.

[35]  D. Velakoulis,et al.  A retrospective study of the impact of lifestyle on age at onset of Huntington disease , 2010, Movement disorders : official journal of the Movement Disorder Society.

[36]  C. Conrad.  A critical review of chronic stress effects on spatial learning and memory , 2010, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[37]  J. Howland,et al.  Converging effects of acute stress on spatial and recognition memory in rodents: A review of recent behavioural and pharmacological findings , 2010, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[38]  N. Wood,et al.  Responses to Environmental Enrichment Differ with Sex and Genotype in a Transgenic Mouse Model of Huntington's Disease , 2010, PloS one.

[39]  A. Hannan,et al.  The neurobiology of brain and cognitive reserve: Mental and physical activity as modulators of brain disorders , 2009, Progress in Neurobiology.

[40]  R. Ferrante,et al.  Mouse models of Huntington's disease and methodological considerations for therapeutic trials. , 2009, Biochimica et biophysica acta.

[41]  V. Luine,et al.  Sex-dependent changes in anxiety, memory, and monoamines following one week of stress , 2009, Physiology & Behavior.

[42]  H. Pijl,et al.  Increased hypothalamic-pituitary-adrenal axis activity in Huntington's disease. , 2009, The Journal of clinical endocrinology and metabolism.

[43]  A. Hannan,et al.  Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease. , 2009, Human molecular genetics.

[44]  M. Hamon,et al.  Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin , 2008, Molecular Psychiatry.

[45]  JaneR . Taylor,et al.  Acute Hippocampal Brain-Derived Neurotrophic Factor Restores Motivational and Forced Swim Performance After Corticosterone , 2008, Biological Psychiatry.

[46]  Brianna N Gaskill,et al.  Home improvement: C57BL/6J mice given more naturalistic nesting materials build better nests. , 2008, Journal of the American Association for Laboratory Animal Science : JAALAS.

[47]  Andreas Bauer,et al.  Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males. , 2008, Human molecular genetics.

[48]  A. Hannan,et al.  Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders , 2008, Neurobiology of Disease.

[49]  K. Tsuritani,et al.  Social isolation rearing‐induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion‐related behaviors in juvenile mice , 2008, Journal of neurochemistry.

[50]  C. Blakemore,et al.  Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease , 2008, BMC Neuroscience.

[51]  A. Hannan,et al.  Gene–environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington’s disease transgenic mice , 2008, Neurobiology of Disease.

[52]  E. Stone,et al.  An anti-immobility effect of exogenous corticosterone in mice. , 2008, European journal of pharmacology.

[53]  J. Schiefer,et al.  Myopathy as a first symptom of Huntington's disease in a Marathon runner , 2007, Movement disorders : official journal of the Movement Disorder Society.

[54]  G. Rebec,et al.  Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease , 2007, Behavioural Brain Research.

[55]  Nathan C. Stam,et al.  Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in huntington’s disease transgenic mice , 2006, Neuroscience.

[56]  A. Hannan,et al.  Enriched environments, experience-dependent plasticity and disorders of the nervous system , 2006, Nature Reviews Neuroscience.

[57]  O. Berton,et al.  Lasting anxiogenic effects of feline predator stress in mice: Sex differences in vulnerability to stress and predicting severity of anxiogenic response from the stress experience , 2006, Physiology & Behavior.

[58]  S. Tabrizi,et al.  Progressive alterations in the hypothalamic-pituitary-adrenal axis in the R6/2 transgenic mouse model of Huntington's disease. , 2006, Human molecular genetics.

[59]  R. Apfelbach,et al.  The effects of predator odors in mammalian prey species: A review of field and laboratory studies , 2005, Neuroscience & Biobehavioral Reviews.

[60]  C. Nemeroff,et al.  The neurobiology of depression: inroads to treatment and new drug discovery. , 2005, The Journal of clinical psychiatry.

[61]  M. Hayden,et al.  Cognitive Dysfunction Precedes Neuropathology and Motor Abnormalities in the YAC128 Mouse Model of Huntington's Disease , 2005, The Journal of Neuroscience.

[62]  J. Csernansky,et al.  Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress , 2004, Neuroscience.

[63]  Yongjun Qin,et al.  Effects of Chronic Stress on Structure and Cell Function in Rat Hippocampus and Hypothalamus , 2004, Stress.

[64]  Y. Fathollahi,et al.  The effects of acute restraint stress and dexamethasone on retrieval of long-term memory in rats: an interaction with opiate system , 2004, Behavioural Brain Research.

[65]  H. Praag,et al.  Can stress cause depression? , 2004, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[66]  Donna L Korol,et al.  Acute stress impairs spatial memory in male but not female rats: influence of estrous cycle , 2004, Pharmacology Biochemistry and Behavior.

[67]  D. Borchelt,et al.  Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice , 2004, Experimental Neurology.

[68]  Karen Marder,et al.  Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[69]  T. Spires,et al.  Environmental Enrichment Rescues Protein Deficits in a Mouse Model of Huntington's Disease, Indicating a Possible Disease Mechanism , 2004, Journal of Neuroscience.

[70]  J. Schneider,et al.  Proneness to psychological distress is associated with risk of Alzheimer’s disease , 2003, Neurology.

[71]  Benno Roozendaal,et al.  Stress and Memory: Opposing Effects of Glucocorticoids on Memory Consolidation and Memory Retrieval , 2002, Neurobiology of Learning and Memory.

[72]  I. Olsson,et al.  Improving housing conditions for laboratory mice: a review of 'environmental enrichment' , 2002, Laboratory animals.

[73]  C. Blakemore,et al.  Environmental enrichment slows disease progression in R6/2 Huntington's disease mice , 2002, Annals of neurology.

[74]  E. Carlson.  Psychometric Study of a Brief Screen for PTSD:Assessing the Impact of Multiple Traumatic Events , 2001, Assessment.

[75]  M. Palkovits,et al.  Stressor specificity of central neuroendocrine responses: implications for stress-related disorders. , 2001, Endocrine reviews.

[76]  V. Luine,et al.  Chronic restraint stress enhances radial arm maze performance in female rats , 2001, Brain Research.

[77]  F. Gage,et al.  Neural consequences of enviromental enrichment , 2000, Nature Reviews Neuroscience.

[78]  A. Morton,et al.  Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene , 2000, Movement disorders : official journal of the Movement Disorder Society.

[79]  E. Gould,et al.  The modulation of Pavlovian memory , 2000, Behavioural Brain Research.

[80]  Colin Blakemore,et al.  Delaying the onset of Huntington's in mice , 2000, Nature.

[81]  A. Morton,et al.  Selective Discrimination Learning Impairments in Mice Expressing the Human Huntington's Disease Mutation , 1999, The Journal of Neuroscience.

[82]  B. McEwen,et al.  Support for a Bimodal Role for Type II Adrenal Steroid Receptors in Spatial Memory , 1999, Neurobiology of Learning and Memory.

[83]  F. Gage,et al.  Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus , 1999, Nature Neuroscience.

[84]  P. Brain,et al.  Refining rodent husbandry: the mouse: Report of the Rodent Refinement Working Party , 1998, Laboratory animals.

[85]  T. Shors,et al.  Stress facilitates classical conditioning in males, but impairs classical conditioning in females through activational effects of ovarian hormones. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[86]  C. McKittrick,et al.  Behavioral and Endocrine Change Following Chronic Predatory Stress , 1998, Physiology & Behavior.

[87]  B. McEwen,et al.  Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment. , 1996, Behavioral neuroscience.

[88]  J. Brandt,et al.  Neuropsychological stability over two years in asymptomatic carriers of the Huntington's disease mutation. , 1996, Journal of neurology, neurosurgery, and psychiatry.

[89]  S. W. Davies,et al.  Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice , 1996, Cell.

[90]  K. Teigen.  Yerkes-Dodson: A Law for all Seasons , 1994 .

[91]  E. D. de Kloet,et al.  The use of various animal models in the study of stress and stress-related phenomena , 1994, Laboratory animals.

[92]  Robert Murison,et al.  Restraint stress in biomedical research: An update , 1994, Neuroscience & Biobehavioral Reviews.

[93]  M. Hayden,et al.  The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease , 1993, Nature Genetics.

[94]  Manish S. Shah,et al.  A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes , 1993, Cell.

[95]  C Weiss,et al.  Stress-induced facilitation of classical conditioning. , 1992, Science.

[96]  D. London,et al.  PATTERNS OF ACTH AND CORTISOL PULSATILITY OVER TWENTY‐FOUR HOURS IN NORMAL MALES AND FEMALES , 1990, Clinical endocrinology.

[97]  P. Willner.  Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case , 1986, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[98]  N. Temkin,et al.  Stress as a Risk Factor for Seizures Among Adults with Epilepsy , 1984, Epilepsia.

[99]  C. Blakemore,et al.  'Super-Enrichment' Reveals Dose-Dependent Therapeutic Effects of Environmental Stimulation in a Transgenic Mouse Model of Huntington's Disease. , 2014, Journal of Huntington's disease.

[100]  F. Guimarães,et al.  Animal models of anxiety disorders and stress. , 2013, Revista brasileira de psiquiatria.

[101]  정윤하.  Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer`s disease model , 2007 .

[102]  B. Christie,et al.  Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways , 2006, Hippocampus.

[103]  E. Altschuler.  Strenuous, intensive, long-term exercise does not prevent or delay the onset of Huntington's disease. , 2006, Medical hypotheses.

[104]  J. Garner.  Stereotypies and other abnormal repetitive behaviors: potential impact on validity, reliability, and replicability of scientific outcomes. , 2005, ILAR journal.

[105]  E. Walker,et al.  The stress cascade and schizophrenia: etiology and onset. , 2003, Schizophrenia bulletin.

[106]  R. Itzhaki,et al.  The significance of environmental factors in the etiology of Alzheimer's disease. , 2002, Journal of Alzheimer's disease : JAD.

[107]  J W Funder,et al.  Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. I. Effect of an audiovisual stimulus and insulin-induced hypoglycemia. , 1989, Neuroendocrinology.