Segmentation and Detection of Colorectal Polyps Using Local Polynomial Approximation

In this paper we introduce a new methodology to segment and detect colorectal polyps in endoscopic images obtained by a wireless capsule endoscopic device. The cornerstone of our approach is the fact that polyps are protrusions emerging from colonic walls. Thus, they can be segmented by simple curvature descriptors. Curvature is based on derivatives, thus very sensitive to noise and image artifacts. Furthermore, the acquired images are sampled on a grid which further complicates the computation of derivatives. To cope with these degradation mechanisms, we use use Local Polynomial Approximation, which, simultaneously, denoise the observed images and provides a continuous representation suitable to compute derivatives. On the top of the image segmentation, we built a support vector machine to classify the segmented regions as polyps or non-polyps. The features used in the classifier are selected with a wrapper selection algorithm (greedy forward feature selection algorithm with support vector machines). The proposed segmentation and detection methodology is tested in several scenarios presenting very good results both using the same video sequences as training data and testing data (cross-feature validation) and different video sequences as training and testing data.

[1]  Ronald M. Summers,et al.  Surface curvature estimation for automatic colonic polyp detection , 2005, SPIE Medical Imaging.

[2]  Jonathan Cohen Comprehensive Atlas of High Resolution Endoscopy and Narrow Band Imaging: Cohen/Comprehensive , 2008 .

[3]  Frans Vos,et al.  Detection and Segmentation of Colonic Polyps on Implicit Isosurfaces by Second Principal Curvature Flow , 2010, IEEE Transactions on Medical Imaging.

[4]  Christopher M. Bishop,et al.  Pattern Recognition and Machine Learning (Information Science and Statistics) , 2006 .

[5]  David Forman,et al.  Population-based cancer survival trends in England and Wales up to 2007: an assessment of the NHS cancer plan for England. , 2009, The Lancet. Oncology.

[6]  Zhuowen Tu,et al.  Probabilistic 3D Polyp Detection in CT Images: The Role of Sample Alignment , 2006, 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'06).

[7]  Y. Nakamura,et al.  Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.

[8]  Nasser M. Nasrabadi,et al.  Pattern Recognition and Machine Learning , 2006, Technometrics.

[9]  Manfredo P. do Carmo,et al.  Differential geometry of curves and surfaces , 1976 .

[10]  Douglas G. Adler,et al.  Wireless Capsule Endoscopy , 2003 .

[11]  Jaakko Astola,et al.  Local Approximation Techniques in Signal and Image Processing (SPIE Press Monograph Vol. PM157) , 2006 .

[12]  J. Potter,et al.  Colon cancer: a review of the epidemiology. , 1993, Epidemiologic reviews.

[13]  Pierre Hellier,et al.  Level Set Methods in an EM Framework for Shape Classification and Estimation , 2004, International Conference on Medical Image Computing and Computer-Assisted Intervention.

[14]  Frans Vos,et al.  On Normalized Convolution to Measure Curvature Features for Automatic Polyp Detection , 2004, MICCAI.

[15]  G. F. Hughes,et al.  On the mean accuracy of statistical pattern recognizers , 1968, IEEE Trans. Inf. Theory.