Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.

[1]  C. Deng,et al.  SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. , 2010, Cancer cell.

[2]  L. Guarente,et al.  Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. , 2009, Genes & development.

[3]  A. Bokov,et al.  Is the oxidative stress theory of aging dead? , 2009, Biochimica et biophysica acta.

[4]  Damian Fermin,et al.  Calorie restriction alters mitochondrial protein acetylation , 2009, Aging cell.

[5]  Gene Kim,et al.  Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. , 2009, The Journal of clinical investigation.

[6]  Q. Tong,et al.  Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle , 2009, Aging.

[7]  M. Mann,et al.  Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions , 2009, Science.

[8]  D. Wallace,et al.  The pathophysiology of mitochondrial disease as modeled in the mouse. , 2009, Genes & development.

[9]  Sterling C. Johnson,et al.  Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys , 2009, Science.

[10]  V. Longo,et al.  SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. , 2008, Cell metabolism.

[11]  M. White,et al.  Response to Comment on "Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis" , 2008, Science.

[12]  Eric Verdin,et al.  Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation , 2007, Molecular and Cellular Biology.

[13]  Anja Voigt,et al.  Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. , 2007, Cell metabolism.

[14]  N. Grishin,et al.  Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. , 2006, Molecular cell.

[15]  Andrew D. Steele,et al.  Increase in Activity During Calorie Restriction Requires Sirt1 , 2005, Science.

[16]  K. Rosenblatt,et al.  Regulation of Oxidative Stress by the Anti-aging Hormone Klotho*♦ , 2005, Journal of Biological Chemistry.

[17]  Emilio Clementi,et al.  Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS , 2005, Science.

[18]  D. Sinclair.  Toward a unified theory of caloric restriction and longevity regulation , 2005, Mechanisms of Ageing and Development.

[19]  M. Emond,et al.  Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria , 2005, Science.

[20]  T. Shirasawa,et al.  Estrogen, Insulin, and Dietary Signals Cooperatively Regulate Longevity Signals to Enhance Resistance to Oxidative Stress in Mice* , 2005, Journal of Biological Chemistry.

[21]  Q. Tong,et al.  SIRT3, a Mitochondrial Sirtuin Deacetylase, Regulates Mitochondrial Function and Thermogenesis in Brown Adipocytes* , 2005, Journal of Biological Chemistry.

[22]  Robert S. Balaban,et al.  Mitochondria, Oxidants, and Aging , 2005, Cell.

[23]  B. Rogina,et al.  Sir2 mediates longevity in the fly through a pathway related to calorie restriction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Myriam Gorospe,et al.  Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase , 2004, Science.

[25]  B. Merry.  Oxidative stress and mitochondrial function with aging – the effects of calorie restriction , 2004, Aging cell.

[26]  S. M. Singh,et al.  Tissue-specific developmental regulation of superoxide dismutase (SOD-1 and SOD-2) activities in genetic strains of mice , 1985, Biochemical Genetics.

[27]  R. S. Sohal,et al.  Effects of age and caloric restriction on glutathione redox state in mice. , 2003, Free radical biology & medicine.

[28]  A. Feinberg,et al.  SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[29]  E. Verdin,et al.  The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase , 2002, The Journal of cell biology.

[30]  A. Bartke,et al.  Reduced Levels of Thyroid Hormones, Insulin, and Glucose, and Lower Body Core Temperature in the Growth Hormone Receptor/Binding Protein Knockout Mouse , 2001, Experimental biology and medicine.

[31]  L. Guarente,et al.  Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans , 2001, Nature.

[32]  A. Richardson,et al.  The anti-ageing action of dietary restriction. , 2001, Novartis Foundation symposium.

[33]  P. Defossez,et al.  Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. , 2000, Science.

[34]  R. Frye,et al.  Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. , 2000, Biochemical and biophysical research communications.

[35]  L. Guarente,et al.  Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase , 2000, Nature.

[36]  M. McVey,et al.  The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. , 1999, Genes & development.

[37]  R. Weindruch,et al.  Oxidative Stress, Caloric Restriction, and Aging , 1996, Science.

[38]  E. Stadtman,et al.  Carbonyl assays for determination of oxidatively modified proteins. , 1994, Methods in enzymology.

[39]  Richard Weindruch,et al.  The Retardation of Aging and Disease by Dietary Restriction , 1988 .

[40]  E. Masoro,et al.  Action of food restriction in delaying the aging process. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[41]  L. Guarente,et al.  SIRT 5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle Citation , 2022 .