Optimal Methods for the Management of Iatrogenic Colonoscopic Perforation

Background/Aims: Colonoscopic perforations have been managed with exploratory laparotomy, and have resulted in some morbidity and mortality. Recently, laparoscopic surgery is commonly performed for this purpose. The aim of this study was to compare the outcomes of several management strategies for iatrogenic colonoscopic perforations. Methods: We retrospectively reviewed the medical records of patients who had been treated for colonoscopic perforation between January 2004 and April 2013 at CHA Bundang Medical Center in Korea. Results: A total of 41 patients with colonoscopic perforation were enrolled. Twenty patients underwent conservative management with a success rate of 90%. Surgical management was performed in 23 patients including two patients who were converted to surgical management after the failure of the initial conservative management. Among 14 patients who underwent surgery at 8 hours after the perforation, there was no considerable difference in adverse outcomes between the laparotomy group and the laparoscopic surgery group. The medical costs and claim rate were 1.45 and 1.87 times greater in the exploratory laparotomy group, respectively. Conclusions: Conservative management of colonoscopic perforation could be an option for patients without overt symptoms of peritonitis or with a small defect size. If surgical management is required, laparoscopic surgery may be considered as the initial procedure even with a delayed diagnosis.

[1]  Jeong Yeon Kim,et al.  Decision-making in the management of colonoscopic perforation: a multicentre retrospective study , 2016, Surgical Endoscopy.

[2]  J. Cha Would You Recommend Screening Colonoscopy for the Very Elderly? , 2014, Intestinal research.

[3]  James Church,et al.  Complications of colonoscopy. , 2013, Gastroenterology clinics of North America.

[4]  S. Post,et al.  Differences in the endoscopic closure of colonic perforation due to diagnostic or therapeutic colonoscopy , 2013, Scandinavian journal of gastroenterology.

[5]  Bo-In Lee,et al.  Endoscopic clip closure versus surgery for the treatment of iatrogenic colon perforations developed during diagnostic colonoscopy: a review of 115,285 patients , 2013, Surgical Endoscopy.

[6]  M. Goldfarb,et al.  Treatment and Outcomes of Iatrogenic Colon Perforations at a Community Teaching Hospital , 2012, The American surgeon.

[7]  J. Wu,et al.  The role of carbon dioxide insufflation in colonoscopy: a systematic review and meta-analysis , 2012, Endoscopy.

[8]  E. di Giulio,et al.  Promptness of diagnosis is the main prognostic factor after colonoscopic perforation , 2012, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[9]  R. Soetikno,et al.  Endoscopic management of colonoscopic perforations (with videos). , 2011, Gastrointestinal endoscopy.

[10]  F. Corcione,et al.  Iatrogenic Colonic Perforation: Repair Using Laparoscopic Technique , 2011, Surgical laparoscopy, endoscopy & percutaneous techniques.

[11]  C. Coimbra,et al.  Laparoscopic repair of colonoscopic perforation: a new standard? , 2011, Surgical Endoscopy.

[12]  J. Castellví,et al.  Colonoscopic perforation: useful parameters for early diagnosis and conservative treatment , 2011, International Journal of Colorectal Disease.

[13]  Gurkirpal Singh,et al.  Risk of perforation from a colonoscopy in adults: a large population-based study. , 2009, Gastrointestinal endoscopy.

[14]  D. Farley,et al.  Surgical management and outcomes of 165 colonoscopic perforations from a single institution. , 2008, Archives of surgery.

[15]  S. Post,et al.  Endoclipping of iatrogenic colonic perforation to avoid surgery , 2008, Surgical Endoscopy.

[16]  J. Milsom,et al.  Initial repair of iatrogenic colon perforation using laparoscopic methods , 2008, Surgical Endoscopy.

[17]  S. Kavic,et al.  Complications of endoscopy. , 2001, American journal of surgery.

[18]  Lotfi Ay,et al.  Selective management of colonoscopic perforations. , 1994 .

[19]  M. Kraus,et al.  Complications in endoscopy of the lower gastrointestinal tract , 1994, Surgical Endoscopy.

[20]  J. Neoptolemos,et al.  Colon perforation during colonoscopy: Surgical versus conservative management , 1991, The British journal of surgery.

[21]  J. Christie,et al.  “Mini-perforation” of the colon—Not all postpolypectomy perforations require laparotomy , 1991, Diseases of the colon and rectum.

[22]  T. Makarawo,et al.  Colonoscopic Perforation Management by Laparoendoscopy: An Algorithm , 2014, JSLS : Journal of the Society of Laparoendoscopic Surgeons.

[23]  Kyoung-Oh Kim,et al.  The Iatrogenic Complications of Colonoscopic Polypectomy: A Multicenter Retrospective Study , 2013 .

[24]  J. Cho,et al.  Conservative Treatment of Colonoscopic Perforations , 2006 .

[25]  C. Yu,et al.  Management of Colonic Perforation during Colonoscopic Procedure. , 2005 .

[26]  Y. Min,et al.  Safety of Conservative Treatment of Colonoscopic Perforation , 2005 .

[27]  A. Y. Lo,et al.  Selective management of colonoscopic perforations. , 1994, Journal of the American College of Surgeons.

[28]  L. E. Smith,et al.  Management of perforation due to colonoscopy , 1983, Diseases of the colon and rectum.