MEDITATIVE THERAPIES FOR REDUCING ANXIETY: A SYSTEMATIC REVIEW AND META‐ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Anxiety disorders are among the most common psychiatric disorders and meditative therapies are frequently sought by patients with anxiety as a complementary therapy. Although multiple reviews exist on the general health benefits of meditation, no review has focused on the efficacy of meditation for anxiety specifically.

[1]  J. Higgins.  Cochrane handbook for systematic reviews of interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration , 2011 .

[2]  S. Perry,et al.  Effects of guided imagery on postoperative outcomes in patients undergoing same-day surgical procedures: a randomized, single-blind study. , 2010, AANA journal.

[3]  J. Kabat-Zinn,et al.  Three-year follow-up and clinical implications of a mindfulness meditation-based stress reduction intervention in the treatment of anxiety disorders. , 1995, General hospital psychiatry.

[4]  Philippe R Goldin,et al.  Effects of mindfulness-based stress reduction (MBSR) on emotion regulation in social anxiety disorder. , 2010, Emotion.

[5]  M. Laopaiboon,et al.  Meditation therapy for anxiety disorders. , 2006, The Cochrane database of systematic reviews.

[6]  Z. Mo,et al.  Use of qigong therapy in the detoxification of heroin addicts. , 2002, Alternative therapies in health and medicine.

[7]  R. Ley.  Blood, breath, and fears: A hyperventilation theory of panic attacks and agoraphobia. , 1985 .

[8]  Olga V. Demler,et al.  Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. , 2005, Archives of general psychiatry.

[9]  J. Wolpe,et al.  Psychotherapy by reciprocal inhibition , 1958, Conditional reflex.

[10]  P. Grossman,et al.  Treating fibromyalgia with mindfulness-based stress reduction: Results from a 3-armed randomized controlled trial , 2011, PAIN®.

[11]  J. Richardson,et al.  Yoga for anxiety: a systematic review of the research evidence , 2005, British Journal of Sports Medicine.

[12]  C. Gilbert,et al.  Clinical Applications of Breathing Regulation , 2003, Behavior modification.

[13]  R. Pandey,et al.  Yogic Versus Conventional Treatment in Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Control Study , 2004, Applied psychophysiology and biofeedback.

[14]  E. Hodnett,et al.  Effects of guided imagery on blood pressure in pregnant women with hypertension: a pilot randomized controlled trial. , 2010, Birth.

[15]  S. von Ammon Cavanaugh,et al.  Placebo effects. Issues for clinical practice in psychiatry and medicine. , 1996, Psychosomatics.

[16]  A. Chiesa,et al.  Mindfulness-based approaches: are they all the same? , 2011, Journal of clinical psychology.

[17]  G. Schwartz,et al.  Effects of Mindfulness-Based Stress Reduction on Medical and Premedical Students , 1998, Journal of Behavioral Medicine.

[18]  C. Gross,et al.  Mindfulness-based stress reduction for solid organ transplant recipients: a randomized controlled trial. , 2010, Alternative therapies in health and medicine.

[19]  W. Roth.  Diversity of effective treatments of panic attacks: what do they have in common? , 2010, Depression and anxiety.

[20]  Gianluca Castelnuovo,et al.  Relaxation training for anxiety: a ten-years systematic review with meta-analysis , 2008, BMC psychiatry.

[21]  A R Jadad,et al.  Assessing the quality of reports of randomized clinical trials: is blinding necessary? , 1996, Controlled clinical trials.

[22]  G. Elkins,et al.  Mind–Body Therapies in Integrative Oncology , 2010, Current treatment options in oncology.

[23]  H. Nagendra,et al.  Effects of a Yoga Program on Cortisol Rhythm and Mood States in Early Breast Cancer Patients Undergoing Adjuvant Radiotherapy: A Randomized Controlled Trial , 2009, Integrative cancer therapies.

[24]  G. Goodwin,et al.  Mindfulness-based Cognitive Therapy (MBCT) in bipolar disorder: Preliminary evaluation of immediate effects on between-episode functioning , 2008, Journal of affective disorders.

[25]  W. Baine,et al.  The Agency for Healthcare Research and Quality , 2006, Italian Journal of Public Health.

[26]  A. Damodaran,et al.  Stress due to exams in medical students--role of yoga. , 1999, Indian journal of physiology and pharmacology.

[27]  G. Andrews,et al.  Modelling the population cost-effectiveness of current and evidence-based optimal treatment for anxiety disorders , 2004, Psychological Medicine.

[28]  Julio Sánchez-Meca,et al.  Psychological treatment of panic disorder with or without agoraphobia: a meta-analysis. , 2010, Clinical psychology review.

[29]  S. Kishiyama,et al.  Randomized controlled trial of yoga and exercise in multiple sclerosis , 2004, Neurology.

[30]  Charles D. Spielberger,et al.  State-Trait Anxiety Inventory for Adults , 2012 .

[31]  D. Bowsher.  Role of the reticular formation in responses to noxious stimulation , 1976, Pain.

[32]  S. Brand,et al.  Influence of Mindfulness Practice on Cortisol and Sleep in Long-Term and Short-Term Meditators , 2012, Neuropsychobiology.

[33]  Daniela Fetter Telles Nunes,et al.  Relaxation and guided imagery program in patients with breast cancer undergoing radiotherapy is not associated with neuroimmunomodulatory effects. , 2007, Journal of psychosomatic research.

[34]  Yvonne M. Caldera,et al.  Mindfulness Meditation, Anxiety Reduction, and Heart Disease: A Pilot Study , 2003, Family & community health.

[35]  Jun Soo Kwon,et al.  The effects of mind–body training on stress reduction, positive affect, and plasma catecholamines , 2010, Neuroscience Letters.

[36]  J. Moskowitz,et al.  Self-report Mindfulness as a Mediator of Psychological Well-being in a Stress Reduction Intervention for Cancer Patients—A Randomized Study , 2010, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[37]  F. Levin,et al.  The Emerging Role of Meditation in Addressing Psychiatric Illness, with a Focus on Substance Use Disorders , 2009, Harvard review of psychiatry.

[38]  R. Sloman.  Relaxation and Imagery for Anxiety and Depression Control in Community Patients With Advanced Cancer , 2002, Cancer nursing.

[39]  D. Clark.  Anxiety disorders: why they persist and how to treat them. , 1999, Behaviour research and therapy.

[40]  Karlijn F. Kuijpers,et al.  Effects of Mindfulness-Based Stress Reduction Intervention on Psychological Well-being and Quality of Life: Is Increased Mindfulness Indeed the Mechanism? , 2008, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[41]  F. Staggers,et al.  The effects of a stress management program in a high security government agency , 1997 .

[42]  L. Carlson,et al.  Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients , 2004, Psychoneuroendocrinology.

[43]  F. Travis,et al.  Pure Consciousness: Distinct Phenomenological and Physiological Correlates of “Consciousness Itself” , 2000, The International journal of neuroscience.

[44]  A. Benedito‐Silva,et al.  Evaluation of Siddha Samadhi Yoga for Anxiety and Depression Symptoms: A Preliminary Study , 2008, Psychological reports.

[45]  R. Trestman,et al.  Systematic review of the efficacy of meditation techniques as treatments for medical illness. , 2006, Journal of alternative and complementary medicine.

[46]  J. Hagelin,et al.  A randomized controlled trial on effects of the Transcendental Meditation program on blood pressure, psychological distress, and coping in young adults. , 2009, American journal of hypertension.

[47]  H. Tsang,et al.  Psychophysiological outcomes of health qigong for chronic conditions: a systematic review. , 2009, Psychophysiology.

[48]  I. Robertson,et al.  Brief mindfulness training for attentional problems after traumatic brain injury: A randomised control treatment trial , 2002 .

[49]  W. Chan,et al.  An evaluation of two behavioral rehabilitation programs, qigong versus progressive relaxation, in improving the quality of life in cardiac patients. , 2006, Journal of alternative and complementary medicine.

[50]  R. Davidson,et al.  Alterations in Brain and Immune Function Produced by Mindfulness Meditation , 2003, Psychosomatic medicine.

[51]  T. T. Haug,et al.  The validity of the Hospital Anxiety and Depression Scale. An updated literature review. , 2002, Journal of psychosomatic research.

[52]  N. Sharma,et al.  Effectiveness of Yoga Therapy in the Treatment of Migraine Without Aura: A Randomized Controlled Trial , 2007, Headache.

[53]  C. Lau,et al.  Randomised controlled trial of qigong in the treatment of mild essential hypertension , 2005, Journal of Human Hypertension.

[54]  L. Carlson,et al.  A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients , 2000, Psychosomatic medicine.

[55]  K. Sancier.  Search for medical applications of qigong with the Qigong Database. , 2001, Journal of alternative and complementary medicine.

[56]  H. Nagendra,et al.  Anxiolytic effects of a yoga program in early breast cancer patients undergoing conventional treatment: a randomized controlled trial. , 2009, Complementary therapies in medicine.

[57]  Sang-Hyuk Lee,et al.  Usefulness of Mindfulness-Based Cognitive Therapy for Treating Insomnia in Patients With Anxiety Disorders: A Pilot Study , 2008, The Journal of nervous and mental disease.

[58]  G. Deng,et al.  Integrative Oncology: Complementary Therapies for Pain, Anxiety, and Mood Disturbance , 2005, CA: a cancer journal for clinicians.

[59]  G. Andersson,et al.  Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot study. , 2010, Journal of behavior therapy and experimental psychiatry.

[60]  D. Ciccone,et al.  Effects of qigong on late-stage complex regional pain syndrome. , 1999, Alternative therapies in health and medicine.

[61]  Chan Mo Kim,et al.  Effectiveness of mindfulness‐based cognitive therapy as an adjuvant to pharmacotherapy in patients with panic disorder or generalized anxiety disorder , 2009, Depression and anxiety.

[62]  R. Manocha.  Why meditation? , 2000, Australian family physician.

[63]  E. Levinson,et al.  The Effects of Meditation on Teacher Perceived Occupational Stress, State and Trait Anxiety, and Burnout. , 1999 .

[64]  C. Ahlgren,et al.  Effects of Qigong in patients with burnout: a randomized controlled trial. , 2009, Journal of rehabilitation medicine.

[65]  M. Price,et al.  Mindfulness-based cognitive therapy for individuals whose lives have been affected by cancer: a randomized controlled trial. , 2010, Journal of consulting and clinical psychology.

[66]  M. Blanca,et al.  Serum Cytokines, Mood and Sleep after a Qigong Program , 2009, Journal of health psychology.

[67]  Christina Ahlgren,et al.  Cognitively Oriented Behavioral Rehabilitation in Combination with Qigong for Patients on Long-Term Sick Leave Because of Burnout: REST—A Randomized Clinical Trial , 2009, International journal of behavioral medicine.

[68]  B. Farrús,et al.  A randomized trial of the effect of training in relaxation and guided imagery techniques in improving psychological and quality‐of‐life indices for gynecologic and breast brachytherapy patients , 2007, Psycho-oncology.

[69]  Alessandro Serretti,et al.  Mindfulness based cognitive therapy for psychiatric disorders: A systematic review and meta-analysis , 2011, Psychiatry Research.

[70]  Jon Kabat-Zinn,et al.  Influence of a Mindfulness Meditation-Based Stress Reduction Intervention on Rates of Skin Clearing in Patients With Moderate to Severe Psoriasis Undergoing Photo Therapy (UVB) and Photochemotherapy (PUVA) , 1998, Psychosomatic medicine.

[71]  N. Raghuram,et al.  Effects of an Integrated Yoga Program in Modulating Psychological Stress and Radiation-Induced Genotoxic Stress in Breast Cancer Patients Undergoing Radiotherapy , 2007, Integrative cancer therapies.

[72]  Susan K. Johnson,et al.  Mindfulness meditation improves cognition: Evidence of brief mental training , 2010, Consciousness and Cognition.

[73]  M. Mahowald,et al.  Mindfulness-based stress reduction versus pharmacotherapy for chronic primary insomnia: a randomized controlled clinical trial. , 2011, Explore.

[74]  Ben Vandermeer,et al.  Meditation practices for health: state of the research. , 2007, Evidence report/technology assessment.

[75]  R. Bennett,et al.  A pilot randomized controlled trial of the Yoga of Awareness program in the management of fibromyalgia , 2010, PAIN®.

[76]  D. Klein.  False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis. , 1993, Archives of general psychiatry.

[77]  David Moher,et al.  A checklist to evaluate a report of a nonpharmacological trial (CLEAR NPT) was developed using consensus. , 2005, Journal of clinical epidemiology.

[78]  Matthew J. Goodman,et al.  Randomized controlled trial of mindfulness‐based stress reduction (MBSR) for survivors of breast cancer , 2009, Psycho-oncology.

[79]  R. Pruchno,et al.  Tai Chi and Low Impact Exercise: Effects on the Physical Functioning and Psychological Well-Being of Older People , 2007 .

[80]  A. Chiesa.  Vipassana meditation: systematic review of current evidence. , 2010, Journal of alternative and complementary medicine.

[81]  T. Kishimoto,et al.  Tai Chi exercise versus rehabilitation for the elderly with cerebral vascular disorder: a single‐blinded randomized controlled trial , 2010, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.

[82]  B. Tomlinson,et al.  The beneficial effects of Tai Chi Chuan on blood pressure and lipid profile and anxiety status in a randomized controlled trial. , 2003, Journal of alternative and complementary medicine.

[83]  Jing-Long Huang,et al.  Effect of relaxation-breathing training on anxiety and asthma signs/symptoms of children with moderate-to-severe asthma: a randomized controlled trial. , 2009, International journal of nursing studies.

[84]  D. Antonacci,et al.  Exercise, yoga, and meditation for depressive and anxiety disorders. , 2010, American family physician.

[85]  M. Oz,et al.  A Pilot Study to Assess the Effects of a Guided Imagery Audiotape Intervention on Psychological Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery , 2010, Holistic nursing practice.

[86]  O. Ulger,et al.  Effects of yoga on the quality of life in cancer patients. , 2010, Complementary therapies in clinical practice.

[87]  Heather Hancock,et al.  A randomised comparative trial of yoga and relaxation to reduce stress and anxiety. , 2007, Complementary therapies in medicine.