Functional impairments in adults with self-reports of diagnosed ADHD: A controlled study of 1001 adults in the community.

OBJECTIVE The objective of this study was to evaluate functional impairments in a nonreferred sample of adults identifying themselves as having been diagnosed with attention-deficit/hyperactivity disorder (ADHD) by a clinician in their community. METHOD We completed a survey in April and May 2003 of a community sample of 500 adults who reported having received a diagnosis of ADHD in the community and 501 gender- and age-matched comparisons from a national sample representative of the U.S. population. RESULTS Adults with self-reports of diagnosed ADHD in the community were significantly less likely to have graduated high school (83% vs. 93% of controls; p < or = .001) or obtain a college degree (19% vs. 26%; p < .01), were less likely to be currently employed (52% vs. 72%; p < or = .001), and had significantly more mean job changes over 10 years (5.4 vs. 3.4 jobs; p < or = .001). They also were significantly more likely to have been arrested (37% vs. 18% of controls; p < or = .001) or divorced (28% vs. 15%; p < or = .001) and were significantly less satisfied (p < or = .001) with their family, social, and professional lives. CONCLUSION Adults who reported having received a diagnosis of ADHD in the community had significant impairment in multiple domains of functioning compared with age- and gender-matched controls without this diagnosis, highly consistent with findings derived from carefully diagnosed referred samples.

[1]  L. Rohde,et al.  Is age-at-onset criterion relevant for the response to methylphenidate in attention-deficit/hyperactivity disorder? , 2007, The Journal of clinical psychiatry.

[2]  Stephen V Faraone,et al.  The effect of stimulant treatment for ADHD on later substance abuse and the potential for medication misuse, abuse, and diversion. , 2007, The Journal of clinical psychiatry.

[3]  B. Franke,et al.  Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[4]  B. Franke,et al.  Association of ADHD with genetic variants in the 5′‐region of the dopamine transporter gene: Evidence for allelic heterogeneity , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[5]  S. Faraone,et al.  Long-term effects of methylphenidate transdermal delivery system treatment of ADHD on growth. , 2007, Journal of the American Academy of Child and Adolescent Psychiatry.

[6]  S. Purcell,et al.  Multivariate genomewide linkage scan of neurocognitive traits and ADHD symptoms: Suggestive linkage to 3q13 , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[7]  B. Franke,et al.  Confirmation that a specific haplotype of the dopamine transporter gene is associated with combined-type ADHD. , 2007, The American journal of psychiatry.

[8]  S. Faraone,et al.  Clinical correlates of ADHD in females: findings from a large group of girls ascertained from pediatric and psychiatric referral sources. , 1999, Journal of the American Academy of Child and Adolescent Psychiatry.

[9]  S. Guze,et al.  Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. , 1970, The American journal of psychiatry.

[10]  S. Faraone,et al.  Atomoxetine and adult attention-deficit/hyperactivity disorder: the effects of comorbidity. , 2006, The Journal of clinical psychiatry.

[11]  S. Faraone,et al.  Discordance Between Psychometric Testing and Questionnaire-Based Definitions of Executive Function Deficits in Individuals With ADHD , 2008, Journal of attention disorders.

[12]  Joseph Biederman,et al.  What Is the Prevalence of Adult ADHD? Results of a Population Screen of 966 Adults , 2005, Journal of attention disorders.

[13]  J. Buitelaar,et al.  [Long-acting medications for the treatment of hyperkinetic disorders - a systematic review and European treatment guideline. Part 1: overview and recommendations]. , 2008, Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie.

[14]  S. Purcell,et al.  Investigation of parent‐of‐origin effects in ADHD candidate genes , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[15]  Joseph Biederman,et al.  The worldwide prevalence of ADHD: is it an American condition? , 2003, World psychiatry : official journal of the World Psychiatric Association.

[16]  S. Purcell,et al.  Further evidence of association between two NET single-nucleotide polymorphisms with ADHD , 2008, Molecular Psychiatry.

[17]  S. Faraone,et al.  The Massachusetts General Hospital studies of gender influences on attention-deficit/hyperactivity disorder in youth and relatives. , 2004, The Psychiatric clinics of North America.

[18]  Stephen V Faraone,et al.  Interpreting estimates of treatment effects: implications for managed care. , 2008, P & T : a peer-reviewed journal for formulary management.

[19]  M. Monuteaux,et al.  Social impairment in girls with ADHD: patterns, gender comparisons, and correlates. , 2001, Journal of the American Academy of Child and Adolescent Psychiatry.

[20]  S. Faraone,et al.  Depression in attention deficit hyperactivity disorder (ADHD) children: "true" depression or demoralization? , 1998, Journal of affective disorders.