EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype

[1]  W. Cookson,et al.  COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix , 2018, Scientific Reports.

[2]  C. Feldman.  Faculty Opinions recommendation of Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study 2015. , 2018, Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature.

[3]  M. Delgado-Rodríguez,et al.  Systematic review and meta-analysis. , 2017, Medicina intensiva.

[4]  Ashutosh Kumar Singh,et al.  Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 , 2016, Lancet.

[5]  C. Cooper,et al.  Increased expression of H19/miR‐675 is associated with a low fat‐free mass index in patients with COPD , 2016, Journal of cachexia, sarcopenia and muscle.

[6]  C. Tanase,et al.  Interstitial Outburst of Angiogenic Factors During Skeletal Muscle Regeneration After Acute Mechanical Trauma , 2015, Anatomical record.

[7]  B. Deurs,et al.  EGFR signaling patterns are regulated by its different ligands , 2014, Growth factors.

[8]  F. Maltais,et al.  Vastus lateralis fiber shift is an independent predictor of mortality in chronic obstructive pulmonary disease. , 2014, American journal of respiratory and critical care medicine.

[9]  F. Maltais,et al.  Regenerative defect in vastus lateralis muscle of patients with chronic obstructive pulmonary disease , 2014, Respiratory Research.

[10]  Andreas Krämer,et al.  Causal analysis approaches in Ingenuity Pathway Analysis , 2013, Bioinform..

[11]  M. Polkey,et al.  Heterogeneity of quadriceps muscle phenotype in chronic obstructive pulmonary disease (Copd); implications for stratified medicine? , 2013, Muscle & nerve.

[12]  Q. Gao,et al.  Therapeutic targeting of EGFR-activated metabolic pathways in glioblastoma , 2013, Expert opinion on investigational drugs.

[13]  T. Efferth.  Signal transduction pathways of the epidermal growth factor receptor in colorectal cancer and their inhibition by small molecules. , 2012, Current medicinal chemistry.

[14]  Zhan-Qiu Yang,et al.  Culture Conditions and Types of Growth Media for Mammalian Cells , 2012 .

[15]  F. Maltais,et al.  Satellite Cells Senescence in Limb Muscle of Severe Patients with COPD , 2012, PloS one.

[16]  J. Brameld,et al.  Myosin heavy chain mRNA isoforms are expressed in two distinct cohorts during C2C12 myogenesis , 2011, Journal of Muscle Research and Cell Motility.

[17]  K. Eriksson,et al.  Exercise capacity in relation to body fat distribution and muscle fibre distribution in elderly male subjects with impaired glucose tolerance, type 2 diabetes and matched controls. , 2011, Diabetes research and clinical practice.

[18]  Carlo Reggiani,et al.  Fiber types in mammalian skeletal muscles. , 2011, Physiological reviews.

[19]  N. Grishin,et al.  Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6 , 2011, Proceedings of the National Academy of Sciences.

[20]  B. Björnsson,et al.  IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder. , 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

[21]  G. Lanfranchi,et al.  Microgenomic Analysis in Skeletal Muscle: Expression Signatures of Individual Fast and Slow Myofibers , 2011, PloS one.

[22]  G. MacBeath,et al.  High- and Low-Affinity Epidermal Growth Factor Receptor-Ligand Interactions Activate Distinct Signaling Pathways , 2011, PloS one.

[23]  J. Schlessinger,et al.  Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.

[24]  T. Gordon,et al.  Satellite cell ablation attenuates short-term fast-to-slow fibre type transformations in rat fast-twitch skeletal muscle , 2009, Pflügers Archiv - European Journal of Physiology.

[25]  D. Gerrard,et al.  Modulation of skeletal muscle fiber type by mitogen‐activated protein kinase signaling , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  S. Hughes,et al.  Mef2s are required for thick filament formation in nascent muscle fibres , 2007, Development.

[27]  Maurice P Zeegers,et al.  Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis , 2007, Thorax.

[28]  D. Gerrard,et al.  Extracellular signal-regulated kinase pathway is differentially involved in beta-agonist-induced hypertrophy in slow and fast muscles. , 2007, American journal of physiology. Cell physiology.

[29]  M. Koutsilieris,et al.  The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology. , 2007, In vivo.

[30]  A. Jimeno,et al.  Pharmacogenomics of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. , 2006, Biochimica et biophysica acta.

[31]  P. Currie,et al.  Scube2 mediates Hedgehog signalling in the zebrafish embryo. , 2006, Developmental biology.

[32]  T. Gordon,et al.  Effect of satellite cell ablation on low‐frequency‐stimulated fast‐to‐slow fibre‐type transitions in rat skeletal muscle , 2006, The Journal of physiology.

[33]  R. Paschke,et al.  Altered fiber distribution and fiber-specific glycolytic and oxidative enzyme activity in skeletal muscle of patients with type 2 diabetes. , 2006, Diabetes care.

[34]  N. Hagiwara,et al.  Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[35]  M. S. Cooper,et al.  Visualizing morphogenesis in transgenic zebrafish embryos using BODIPY TR methyl ester dye as a vital counterstain for GFP , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[36]  J. Hawley,et al.  Open access, freely available online Primer Skeletal Muscle Fiber Type: Influence on Contractile and Metabolic Properties , 2022 .

[37]  R. Evans,et al.  Regulation of Muscle Fiber Type and Running Endurance by PPARδ , 2004, PLoS biology.

[38]  L. Zon,et al.  Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects , 2003, Mechanisms of Development.

[39]  M. Sandri,et al.  Electrotransfer in differentiated myotubes: a novel, efficient procedure for functional gene transfer. , 2003, Experimental cell research.

[40]  H. van Mameren,et al.  Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease. , 2002, The American journal of clinical nutrition.

[41]  H. van Mameren,et al.  Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease , 2002, European Respiratory Journal.

[42]  C. Emerson,et al.  Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. , 2002, Annual review of cell and developmental biology.

[43]  E. Richter,et al.  Relationship between muscle fibre composition, glucose transporter protein 4 and exercise training: possible consequences in non-insulin-dependent diabetes mellitus. , 2001, Acta physiologica Scandinavica.

[44]  Ming Li,et al.  Stimulation of the Mitogen-activated Protein Kinase Cascade and Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor by Hepatopoietin* , 2000, The Journal of Biological Chemistry.

[45]  E. Richter,et al.  Fiber type-specific expression of GLUT4 in human skeletal muscle: influence of exercise training. , 2000, Diabetes.

[46]  T. Lømo,et al.  Ras is involved in nerve-activity-dependent regulation of muscle genes , 2000, Nature Cell Biology.

[47]  A. Kriketos,et al.  Interrelationships between muscle fibre type, substrate oxidation and body fat , 1999, International Journal of Obesity.

[48]  T. Lømo,et al.  Fast to slow transformation of denervated and electrically stimulated rat muscle , 1998, The Journal of physiology.

[49]  F. Maltais,et al.  Skeletal muscle adaptation to endurance training in patients with chronic obstructive pulmonary disease. , 1996, American journal of respiratory and critical care medicine.

[50]  K. Swedberg,et al.  Skeletal muscle fiber composition and capillarization in patients with chronic heart failure: relation to exercise capacity and central hemodynamics. , 1995, Journal of cardiac failure.

[51]  E. Wagner,et al.  Strain-dependent epithelial defects in mice lacking the EGF receptor. , 1995, Science.

[52]  A. Levitzki,et al.  Tyrosine kinase inhibition: an approach to drug development. , 1995, Science.

[53]  M. Westerfield.  The zebrafish book : a guide for the laboratory use of zebrafish (Danio rerio) , 1995 .

[54]  A. Levitzki,et al.  Epidermal-growth-factor-dependent activation of the src-family kinases. , 1994, European journal of biochemistry.

[55]  J. Schlessinger,et al.  Signaling by Receptor Tyrosine Kinases , 1993 .

[56]  H. Drexler,et al.  Alterations of Skeletal Muscle in Chronic Heart Failure , 1992, Circulation.

[57]  D. Yaffe,et al.  Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle , 1977, Nature.

[58]  L. Edström,et al.  Differential histochemical effects of muscle contractions on phosphorylase and glycogen in various types of fibres: relation to fatigue. , 1968, Journal of neurology, neurosurgery, and psychiatry.