Glucocorticoids, metabolism and metabolic diseases

[1]  Min Jung Park,et al.  Transcriptional repression of the gluconeogenic gene PEPCK by the orphan nuclear receptor SHP through inhibitory interaction with C/EBPalpha. , 2007, The Biochemical journal.

[2]  J. Seckl,et al.  Liver-selective transgene rescue of hypothalamic-pituitary-adrenal axis dysfunction in 11beta-hydroxysteroid dehydrogenase type 1-deficient mice. , 2007, Endocrinology.

[3]  R. Knutsen,et al.  An afferent vagal nerve pathway links hepatic PPARalpha activation to glucocorticoid-induced insulin resistance and hypertension. , 2007, Cell metabolism.

[4]  D. Granner,et al.  Insulin represses phosphoenolpyruvate carboxykinase gene transcription by causing the rapid disruption of an active transcription complex: a potential epigenetic effect. , 2007, Molecular endocrinology.

[5]  B. Walker Cortisol—cause and cure for metabolic syndrome? , 2006, Diabetic medicine : a journal of the British Diabetic Association.

[6]  B. Walker,et al.  Tissue Production of Cortisol by 11β‐Hydroxysteroid Dehydrogenase Type 1 and Metabolic Disease , 2006, Annals of the New York Academy of Sciences.

[7]  D. DeFranco,et al.  Mechanisms of Disease: regulation of glucocorticoid and receptor levels—impact on the metabolic syndrome , 2006, Nature Clinical Practice Endocrinology &Metabolism.

[8]  Nicholas Ling,et al.  Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF‐κB‐independent, FoxO1‐dependent mechanism , 2006 .

[9]  F. Gonzalez,et al.  Apolipoprotein A-IV is regulated by nutritional and metabolic stress: involvement of glucocorticoids, HNF-4α, and PGC-1αs⃞ Published, JLR Papers in Press, August 23, 2006. , 2006, Journal of Lipid Research.

[10]  C. Kahn,et al.  Skeletal Muscle-Selective Knockout of LKB1 Increases Insulin Sensitivity, Improves Glucose Homeostasis, and Decreases TRB3 , 2006, Molecular and Cellular Biology.

[11]  L. Nieman,et al.  Therapeutic doses of glucocorticoids: implications for oral medicine. , 2006, Oral diseases.

[12]  W. Mitch,et al.  Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. , 2006, Endocrinology.

[13]  T. Friedman,et al.  Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice. , 2006, Endocrinology.

[14]  A. Goldfine,et al.  Inflammation and insulin resistance. , 2006, The Journal of clinical investigation.

[15]  P. Neufer,et al.  Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. , 2006, Cell metabolism.

[16]  J. Yates,et al.  TRB3 Links the E3 Ubiquitin Ligase COP1 to Lipid Metabolism , 2006, Science.

[17]  A. Amanso,et al.  Distinct regulation of IRS proteins in adipose tissue from obese aged and dexamethasone-treated rats , 2006, Endocrine.

[18]  A. Lonardo,et al.  'Endocrine NAFLD' a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis. , 2006, Journal of hepatology.

[19]  F. Lang,et al.  Dexamethasone Induces Cell Death in Insulin-Secreting Cells, an Effect Reversed by Exendin-4 , 2006, Diabetes.

[20]  Guo-xian Ding,et al.  Role of 11-beta-hydroxysteroid dehydrogenase type 1 in differentiation of 3T3-L1 cells and in rats with diet-induced obesity , 2006, Acta Pharmacologica Sinica.

[21]  E. Lander,et al.  Reactive oxygen species have a causal role in multiple forms of insulin resistance , 2006, Nature.

[22]  Minghan Wang Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for the treatment of metabolic syndrome. , 2006, Current opinion in investigational drugs.

[23]  S. Welle,et al.  Myofibrillar protein synthesis in myostatin-deficient mice. , 2006, American journal of physiology. Endocrinology and metabolism.

[24]  H. Chi,et al.  Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[25]  R. Goldin,et al.  Mouse models in non‐alcoholic fatty liver disease and steatohepatitis research , 2006, International journal of experimental pathology.

[26]  F. Bosch,et al.  Adipose overexpression of phosphoenolpyruvate carboxykinase leads to high susceptibility to diet-induced insulin resistance and obesity. , 2006, Diabetes.

[27]  M. Potter,et al.  Essential Role of MAPK Phosphatase-1 in the Negative Control of Innate Immune Responses , 2006, The Journal of Immunology.

[28]  G. Farrell,et al.  Nonalcoholic fatty liver disease: From steatosis to cirrhosis , 2006, Hepatology.

[29]  J. Mages,et al.  Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock , 2006, The Journal of experimental medicine.

[30]  Xiaomei Meng,et al.  MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock , 2006, The Journal of experimental medicine.

[31]  J. Buckingham Glucocorticoids: exemplars of multi‐tasking , 2006, British journal of pharmacology.

[32]  D. Annane,et al.  Glucocorticoids and sepsis. , 2005, Minerva anestesiologica.

[33]  J. K. Oeser,et al.  The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements. , 2005, Molecular endocrinology.

[34]  P. Stewart,et al.  Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome , 2005, Nature Clinical Practice Endocrinology &Metabolism.

[35]  G. Marchesini,et al.  Insulin resistance: A metabolic pathway to chronic liver disease , 2005, Hepatology.

[36]  G. Haegeman,et al.  A fully dissociated compound of plant origin for inflammatory gene repression. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[37]  H. Cohen,et al.  Glucocorticoids Regulate Transcription of the Gene for Phosphoenolpyruvate Carboxykinase in the Liver via an Extended Glucocorticoid Regulatory Unit* , 2005, Journal of Biological Chemistry.

[38]  H. Beck-Nielsen,et al.  Increased expression of 11β‐hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes , 2005, European journal of clinical investigation.

[39]  D. Glass,et al.  Skeletal muscle hypertrophy and atrophy signaling pathways. , 2005, The international journal of biochemistry & cell biology.

[40]  Jonathan Schug,et al.  Glucocorticoid Receptor-Dependent Gene Regulatory Networks , 2005, PLoS genetics.

[41]  L. Abrahmsén,et al.  Effect of High-fat Diet on KKAy and ob/ob Mouse Liver and Adipose Tissue Corticosterone and 11-dehydrocorticosterone Concentrations , 2005, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[42]  L. Öhman,et al.  Hepatic Glucocorticoid Receptor Antagonism Is Sufficient to Reduce Elevated Hepatic Glucose Output and Improve Glucose Control in Animal Models of Type 2 Diabetes , 2005, Journal of Pharmacology and Experimental Therapeutics.

[43]  B. Monia,et al.  Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice. , 2005, Metabolism: clinical and experimental.

[44]  B. Monia,et al.  Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism. , 2005, Diabetes.

[45]  D. Alexander,et al.  Serum- and glucocorticoid-inducible kinase 1 (SGK1) mediates glucocorticoid-induced inhibition of insulin secretion. , 2005, Diabetes.

[46]  S. Shoelson,et al.  Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB , 2005, Nature Medicine.

[47]  M. Stoffel,et al.  Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes , 2004, Nature.

[48]  Morihiro Matsuda,et al.  Increased oxidative stress in obesity and its impact on metabolic syndrome. , 2004, The Journal of clinical investigation.

[49]  L. Muglia,et al.  Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice , 2004, Hepatology.

[50]  Jonathan C. Cohen,et al.  Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.

[51]  S. Price,et al.  Insulin-like growth factor I: the yin and yang of muscle atrophy. , 2004, Endocrinology.

[52]  T. V. Geldern Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes. , 2004 .

[53]  Jeremy W Tomlinson,et al.  11 (cid:1) -Hydroxysteroid Dehydrogenase Type 1: A Tissue-Specific Regulator of Glucocorticoid Response , 2004 .

[54]  S. Reddy,et al.  Potential Role for Mitogen-Activated Protein Kinase Phosphatase-1 in the Development of Atherosclerotic Lesions in Mouse Models , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[55]  D. Granner,et al.  The Synergistic Effect of Dexamethasone and All-trans-retinoic Acid on Hepatic Phosphoenolpyruvate Carboxykinase Gene Expression Involves the Coactivator p300* , 2004, Journal of Biological Chemistry.

[56]  D. Befroy,et al.  Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease* , 2004, Journal of Biological Chemistry.

[57]  J. Horton,et al.  Molecular mediators of hepatic steatosis and liver injury. , 2004, The Journal of clinical investigation.

[58]  C. Kellendonk,et al.  Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. , 2004, Molecular endocrinology.

[59]  G. Chrousos,et al.  Interaction of the Glucocorticoid Receptor and the Chicken Ovalbumin Upstream Promoter‐Transcription Factor II (COUP‐TFII): Implications for the Actions of Glucocorticoids on Glucose, Lipoprotein, and Xenobiotic Metabolism , 2004, Annals of the New York Academy of Sciences.

[60]  G. Yancopoulos,et al.  The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. , 2004, Molecular cell.

[61]  J. Seckl,et al.  Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[62]  E. Sternberg,et al.  Role of the hypothalamic-pituitary-adrenal axis, glucocorticoids and glucocorticoid receptors in toxic sequelae of exposure to bacterial and viral products. , 2004, The Journal of endocrinology.

[63]  Marco Sandri,et al.  Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy , 2004, Cell.

[64]  Marc Montminy,et al.  PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 , 2004, Nature Medicine.

[65]  D. Taillandier,et al.  Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles. , 2004, The Biochemical journal.

[66]  C. Ostenson,et al.  Aged transgenic mice with increased glucocorticoid sensitivity in pancreatic beta-cells develop diabetes. , 2004, Diabetes.

[67]  A. Goldberg,et al.  Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[68]  K. Asadullah,et al.  Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[69]  T. Furuyama,et al.  Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. , 2003, The Biochemical journal.

[70]  A. Barthel,et al.  Novel concepts in insulin regulation of hepatic gluconeogenesis. , 2003, American journal of physiology. Endocrinology and metabolism.

[71]  C. Kahn,et al.  Tissue-specific Ablation of the GLUT4 Glucose Transporter or the Insulin Receptor Challenges Assumptions about Insulin Action and Glucose Homeostasis* , 2003, Journal of Biological Chemistry.

[72]  V. Drapeau,et al.  Is visceral obesity a physiological adaptation to stress? , 2003, Panminerva medica.

[73]  S. Tilghman,et al.  Glyceroneogenesis and the Triglyceride/Fatty Acid Cycle* , 2003, Journal of Biological Chemistry.

[74]  S. Bhasin,et al.  Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. , 2003, American journal of physiology. Endocrinology and metabolism.

[75]  M. Alessi,et al.  Expression of the mRNAs coding for the glucocorticoid receptor isoforms in obesity. , 2003, Obesity research.

[76]  R. Knutsen,et al.  Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor–null mice , 2003, Nature Medicine.

[77]  K. Sunagawa,et al.  Differential Gene Expression in the Rat Skeletal and Heart Muscle in Glucocorticoid-Induced Myopathy: Analysis by Microarray , 2003, Cardiovascular Drugs and Therapy.

[78]  J. Flier,et al.  Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. , 2003, The Journal of clinical investigation.

[79]  Q. Boese,et al.  Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[80]  Marc Montminy,et al.  TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver , 2003, Science.

[81]  R. Ross,et al.  Visceral fat and liver fat are independent predictors of metabolic risk factors in men. , 2003, American journal of physiology. Endocrinology and metabolism.

[82]  Bruce M. Spiegelman,et al.  Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction , 2003, Nature.

[83]  C. Schild-Poulter,et al.  Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex , 2003, The EMBO journal.

[84]  H. Cohen,et al.  Glucocorticoids Repress Transcription of Phosphoenolpyruvate Carboxykinase (GTP) Gene in Adipocytes by Inhibiting Its C/EBP-mediated Activation* , 2003, The Journal of Biological Chemistry.

[85]  P. Puigserver,et al.  Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): Requirement for hepatocyte nuclear factor 4α in gluconeogenesis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[86]  P. Puigserver,et al.  Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. , 2003, Endocrine reviews.

[87]  J. Stephens,et al.  STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. , 2003, Diabetes.

[88]  J. Gustafsson,et al.  Glucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHP* , 2002, The Journal of Biological Chemistry.

[89]  M. Lombès,et al.  Brown adipocytes are novel sites of expression and regulation of adiponectin and resistin , 2002, FEBS letters.

[90]  J. Saklatvala,et al.  Dexamethasone Causes Sustained Expression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase 1 and Phosphatase-Mediated Inhibition of MAPK p38 , 2002, Molecular and Cellular Biology.

[91]  Khusru Asadullah,et al.  Mechanisms involved in the side effects of glucocorticoids. , 2002, Pharmacology & therapeutics.

[92]  Joseph L Evans,et al.  Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. , 2002, Endocrine reviews.

[93]  J. Tata Signalling through nuclear receptors , 2002, Nature Reviews Molecular Cell Biology.

[94]  D. Scott,et al.  A Point Mutation of the AF2 Transactivation Domain of the Glucocorticoid Receptor Disrupts Its Interaction with Steroid Receptor Coactivator 1* , 2002, The Journal of Biological Chemistry.

[95]  A. Häkkinen,et al.  Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. , 2002, The Journal of clinical endocrinology and metabolism.

[96]  W. Mitch,et al.  Ubiquitin (UbC) Expression in Muscle Cells Is Increased by Glucocorticoids through a Mechanism Involving Sp1 and MEK1* , 2002, The Journal of Biological Chemistry.

[97]  G. Lewis,et al.  Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. , 2002, Endocrine reviews.

[98]  C. Byrne,et al.  Increased glucocorticoid receptor expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic syndrome. , 2002, Diabetes.

[99]  A. Casellas,et al.  Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance. , 2002, Diabetes.

[100]  J. Burén,et al.  Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in primary cultured rat adipocytes. , 2002, European journal of endocrinology.

[101]  A. Saltiel,et al.  Insulin signaling pathways in time and space. , 2002, Trends in cell biology.

[102]  S. Bhasin,et al.  Endogenous expression and localization of myostatin and its relation to myosin heavy chain distribution in C2C12 skeletal muscle cells , 2002, Journal of cellular physiology.

[103]  R. Paschke,et al.  Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. , 2002, Biochemical and biophysical research communications.

[104]  S. Tilghman,et al.  A mutation in the peroxisome proliferator-activated receptor γ-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[105]  O. Kassel,et al.  Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP‐1 , 2001, The EMBO journal.

[106]  C. Kahn,et al.  Insulin signalling and the regulation of glucose and lipid metabolism , 2001, Nature.

[107]  J. Flier,et al.  A Transgenic Model of Visceral Obesity and the Metabolic Syndrome , 2001, Science.

[108]  John J. Mullins,et al.  Improved Lipid and Lipoprotein Profile, Hepatic Insulin Sensitivity, and Glucose Tolerance in 11β-Hydroxysteroid Dehydrogenase Type 1 Null Mice* , 2001, The Journal of Biological Chemistry.

[109]  D. Accili,et al.  The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. , 2001, The Journal of clinical investigation.

[110]  H. Vestergaard,et al.  Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes. , 2001, Clinical science.

[111]  J. Beechem,et al.  Accessory Factors Facilitate the Binding of Glucocorticoid Receptor to the Phosphoenolpyruvate Carboxykinase Gene Promoter* , 2001, The Journal of Biological Chemistry.

[112]  D J Glass,et al.  Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy , 2001, Science.

[113]  A. Kralli,et al.  PGC-1, a versatile coactivator , 2001, Trends in Endocrinology & Metabolism.

[114]  G. Sesti,et al.  Defects of the insulin receptor substrate (IRS) system in human metabolic disorders , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[115]  V. Baracos Management of muscle wasting in cancer‐associated cachexia , 2001, Cancer.

[116]  Marc Montminy,et al.  CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 , 2001, Nature.

[117]  Guillaume Adelmant,et al.  Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 , 2001, Nature.

[118]  R. O’Brien,et al.  Insulin-regulated gene expression. , 2001, Biochemical Society transactions.

[119]  J. Dixon,et al.  Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. , 2001, Gastroenterology.

[120]  B. Walker,et al.  Printed in U.S.A. Copyright © 2001 by The Endocrine Society Minireview: 11�-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action* , 2000 .

[121]  B. Walker,et al.  Elevated plasma cortisol in glucose-intolerant men: differences in responses to glucose and habituation to venepuncture. , 2001, The Journal of clinical endocrinology and metabolism.

[122]  A. Saltiel New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes , 2001, Cell.

[123]  D. Granner,et al.  Role of Accessory Factors and Steroid Receptor Coactivator 1 in the Regulation of Phosphoenolpyruvate Carboxykinase Gene Transcription by Glucocorticoids* , 2001, The Journal of Biological Chemistry.

[124]  G. Shulman,et al.  Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver , 2001, Nature.

[125]  O. Shah,et al.  Glucocorticoids oppose translational control by leucine in skeletal muscle. , 2000, American journal of physiology. Endocrinology and metabolism.

[126]  T. Asano,et al.  Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction. , 2000, Diabetes.

[127]  K. Soumano,et al.  Glucocorticoids inhibit the transcriptional response of the uncoupling protein-1 gene to adrenergic stimulation in a brown adipose cell line , 2000, Molecular and Cellular Endocrinology.

[128]  C. Kahn,et al.  Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. , 2000, Molecular cell.

[129]  R. Newton Molecular mechanisms of glucocorticoid action: what is important? , 2000, Thorax.

[130]  C Osmond,et al.  Low birth weight predicts elevated plasma cortisol concentrations in adults from 3 populations. , 2000, Hypertension.

[131]  P. Kopelman Obesity as a medical problem , 2000, Nature.

[132]  A. Kralli,et al.  A Tissue-Specific Coactivator of Steroid Receptors, Identified in a Functional Genetic Screen , 2000, Molecular and Cellular Biology.

[133]  G. Shulman,et al.  Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice* , 2000, The Journal of Biological Chemistry.

[134]  P. Björntorp,et al.  The hypothalamic–pituitary–adrenal axis activity as a predictor of cardiovascular disease, type 2 diabetes and stroke , 2000, Journal of internal medicine.

[135]  B. Walker,et al.  Understanding the Role of Glucocorticoids in Obesity: Tissue-Specific Alterations of Corticosterone Metabolism in Obese Zucker Rats1. , 2000, Endocrinology.

[136]  A. Saltiel,et al.  Signaling pathways in insulin action: molecular targets of insulin resistance. , 2000, The Journal of clinical investigation.

[137]  Guillaume Adelmant,et al.  Activation of PPARγ coactivator-1 through transcription factor docking , 1999 .

[138]  G. Marchesini,et al.  Association of nonalcoholic fatty liver disease with insulin resistance. , 1999, The American journal of medicine.

[139]  P. Björntorp Neuroendocrine perturbations as a cause of insulin resistance , 1999, Diabetes/metabolism research and reviews.

[140]  S. Malkoski,et al.  Composite glucocorticoid regulation at a functionally defined negative glucocorticoid response element of the human corticotropin-releasing hormone gene. , 1999, Molecular endocrinology.

[141]  J. Foster,et al.  Regulation of glucose production by the liver. , 1999, Annual review of nutrition.

[142]  J. Vandenhaute,et al.  Antiglucocorticoid activity of hepatocyte nuclear factor-6. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[143]  Y. Deshaies,et al.  Modulation of triglyceride metabolism by glucocorticoids in diet-induced obesity. , 1999, The American journal of physiology.

[144]  G. Shulman,et al.  Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. , 1999, Diabetes.

[145]  B. Walker,et al.  Glucocorticoids and insulin resistance: old hormones, new targets. , 1999, Clinical science.

[146]  J. Wang,et al.  The phosphoenolpyruvate carboxykinase gene glucocorticoid response unit: identification of the functional domains of accessory factors HNF3 beta (hepatic nuclear factor-3 beta) and HNF4 and the necessity of proper alignment of their cognate binding sites. , 1999, Molecular endocrinology.

[147]  R. Walther,et al.  Identification of a cAMP response element within the glucose- 6-phosphatase hydrolytic subunit gene promoter which is involved in the transcriptional regulation by cAMP and glucocorticoids in H4IIE hepatoma cells. , 1999, The Biochemical journal.

[148]  D. Scott,et al.  CCAAT/Enhancer-binding Protein β Is an Accessory Factor for the Glucocorticoid Response from the cAMP Response Element in the Rat Phosphoenolpyruvate Carboxykinase Gene Promoter* , 1999, The Journal of Biological Chemistry.

[149]  B Lin,et al.  Hepatocyte nuclear factor 1alpha is an accessory factor required for activation of glucose-6-phosphatase gene transcription by glucocorticoids. , 1998, DNA and cell biology.

[150]  M. Olive,et al.  Life without white fat: a transgenic mouse. , 1998, Genes & development.

[151]  P De Meyts,et al.  Inhibition by insulin of glucocorticoid-induced gene transcription: involvement of the ligand-binding domain of the glucocorticoid receptor and independence from the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. , 1998, Molecular endocrinology.

[152]  J. Raber Detrimental effects of chronic hypothalamic—pituitary—adrenal axis activation , 1998, Molecular Neurobiology.

[153]  K. Kaestner,et al.  DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival , 1998, Cell.

[154]  M. White,et al.  The IRS-signalling system: A network of docking proteins that mediate insulin action , 1998, Molecular and Cellular Biochemistry.

[155]  D. Webb,et al.  Increased glucocorticoid activity in men with cardiovascular risk factors. , 1998, Hypertension.

[156]  J. Wang,et al.  Further characterization of the glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene. The role of the glucocorticoid receptor-binding sites. , 1998, Molecular endocrinology.

[157]  P. Puigserver,et al.  A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis , 1998, Cell.

[158]  G. Gnoni,et al.  Short‐term effect of dexamethasone on fatty acid and cholesterol synthesis in isolated rat hepatocytes , 1998, Biochemistry and molecular biology international.

[159]  B. Walker,et al.  Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Elevated Plasma Cortisol Concentrations: A Link between Low Birth Weight and the Insulin Resistance Syndrome?* , 2022 .

[160]  M. Glorian,et al.  Glucocorticoids repress induction by thiazolidinediones, fibrates, and fatty acids of phosphoenolpyruvate carboxykinase gene expression in adipocytes , 1998, Journal of cellular biochemistry.

[161]  I. Macdonald,et al.  Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue. , 1998, The Journal of clinical endocrinology and metabolism.

[162]  H. Sul,et al.  Understanding adipocyte differentiation. , 1998, Physiological reviews.

[163]  Edwards,et al.  11 b-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress , 1997 .

[164]  J. Friedman,et al.  Phosphoenolpyruvate Carboxykinase (GTP) Gene Transcription and Hyperglycemia Are Regulated by Glucocorticoids in Genetically Obesedb/db Transgenic Mice* , 1997, The Journal of Biological Chemistry.

[165]  C. Östenson,et al.  Pancreatic beta cells are important targets for the diabetogenic effects of glucocorticoids. , 1997, The Journal of clinical investigation.

[166]  A. Saltiel,et al.  Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes. , 1997, The Biochemical journal.

[167]  D. Pessayre,et al.  Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid beta-oxidation. , 1997, The American journal of physiology.

[168]  A. Ullrich,et al.  A family of proteins that inhibit signalling through tyrosine kinase receptors , 1997, Nature.

[169]  B. Thorens,et al.  Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells , 1997, The Journal of Biological Chemistry.

[170]  P. Gilon,et al.  Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets. , 1997, The Journal of clinical investigation.

[171]  John A. Mitchell,et al.  The Orphan Receptor COUP-TF Binds to a Third Glucocorticoid Accessory Factor Element within the Phosphoenolpyruvate Carboxykinase Gene Promoter* , 1996, The Journal of Biological Chemistry.

[172]  B. Spiegelman,et al.  Adipogenesis and Obesity: Rounding Out the Big Picture , 1996, Cell.

[173]  N. Wong,et al.  Glucocorticoid increases rat apolipoprotein A-I promoter activity. , 1996, Journal of lipid research.

[174]  Z. Wu,et al.  Induction of peroxisome proliferator-activated receptor gamma during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPbeta, C/EBPdelta, and glucocorticoids , 1996, Molecular and cellular biology.

[175]  J. Wang,et al.  Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. , 1996, Molecular endocrinology.

[176]  J. Auwerx,et al.  Transcriptional induction of rat liver apolipoprotein A-I gene expression by glucocorticoids requires the glucocorticoid receptor and a labile cell-specific protein. , 1996, European journal of biochemistry.

[177]  J. Ward,et al.  Glucose–6–phosphatase dependent substrate transport in the glycogen storage disease type–1a mouse , 1996, Nature Genetics.

[178]  H. Pijl,et al.  Bodyweight Change as an Adverse Effect of Drug Treatment , 1996, Drug safety.

[179]  L. Groop,et al.  The effect of (steroid) immunosuppression on skeletal muscle glycogen metabolism in patients after kidney transplantation. , 1996, Transplantation.

[180]  D. Schmoll,et al.  Cloning and sequencing of the 5′ region of the human glucose‐6‐phosphatase gene: transcriptional regulation by cAMP, insulin and glucocorticoids in H4IIE hepatoma cells , 1996, FEBS letters.

[181]  G. Kilroy,et al.  Abnormal regulation of hepatic glucocorticoid receptor mRNA and receptor protein distribution in the obese Zucker rat. , 1996, Obesity research.

[182]  N. Agell,et al.  Muscle hypercatabolism during cancer cachexia is not reversed by the glucocorticoid receptor antagonist RU38486. , 1996, Cancer letters.

[183]  J. Wang,et al.  Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids. , 1996, The Journal of clinical investigation.

[184]  A. Aguzzi,et al.  Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. , 1995, Genes & development.

[185]  G. Cooney,et al.  Amelioration of High-Fat Feeding–Induced Insulin Resistance in Skeletal Muscle With the Antiglucocorticoid RU486 , 1995, Diabetes.

[186]  S. Weinstein,et al.  Glucocorticoid-Induced Insulin Resistance: Dexamethasone Inhibits the Activation of Glucose Transport in Rat Skeletal Muscle by Both Insulin- and Non-Insulin-Related Stimuli , 1995, Diabetes.

[187]  J. Wang,et al.  Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes , 1995, Molecular and cellular biology.

[188]  F. Sladek,et al.  The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[189]  B. Spiegelman,et al.  PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene , 1995, Molecular and cellular biology.

[190]  C. Kahn,et al.  Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene , 1994, Nature.

[191]  G. Rousseau,et al.  Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver. , 1994, The Biochemical journal.

[192]  P. Kern,et al.  Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes. , 1994, Journal of lipid research.

[193]  P. Angrand,et al.  Response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids depends on the integrity of the cAMP pathway. , 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[194]  R. O’Brien,et al.  Integration of multiple signals through a complex hormone response unit in the phosphoenolpyruvate carboxykinase gene promoter. , 1994, Molecular endocrinology.

[195]  P. G. Quinn,et al.  Involvement of 3',5'-cyclic adenosine monophosphate regulatory element binding protein (CREB) in both basal and hormone-mediated expression of the phosphoenolpyruvate carboxykinase (PEPCK) gene. , 1993, Molecular endocrinology.

[196]  C. Kahn,et al.  Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. , 1993, The Journal of clinical investigation.

[197]  F. Giorgino,et al.  Glucocorticoid regulation of insulin receptor and substrate IRS-1 tyrosine phosphorylation in rat skeletal muscle in vivo. , 1993, The Journal of clinical investigation.

[198]  A. Goldberg,et al.  Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. , 1993, The American journal of physiology.

[199]  K. Yamamoto,et al.  Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. , 1993, The Journal of biological chemistry.

[200]  A. Moorman,et al.  Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP). , 1993, The Journal of biological chemistry.

[201]  E. Noisin,et al.  Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex , 1992, Molecular and cellular biology.

[202]  A. Srivastava,et al.  Effect of hypercorticism on regulation of skeletal muscle glycogen metabolism by epinephrine. , 1992, The American journal of physiology.

[203]  A. Consoli Role of Liver in Pathophysiology of NIDDM , 1992, Diabetes Care.

[204]  J. Liu,et al.  Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements. , 1991, The Journal of biological chemistry.

[205]  R. Phillips,et al.  Hormonal Factors Associated with Weight Loss in Patients with Advanced Breast Cancer , 1991, Annals of clinical biochemistry.

[206]  P. Björntorp Adipose tissue distribution and function. , 1991, International journal of obesity.

[207]  G. Berghe The role of the liver in metabolic homeostasis: Implications for inborn errors of metabolism , 1991, Journal of Inherited Metabolic Disease.

[208]  M. Wabitsch,et al.  Control of terminal differentiation of adipose precursor cells by glucocorticoids. , 1991, Journal of lipid research.

[209]  P. Björntorp,et al.  Steroid hormone receptors in human adipose tissues. , 1990, The Journal of clinical endocrinology and metabolism.

[210]  D. York,et al.  Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats. , 1990, The American journal of physiology.

[211]  J. Gustafsson,et al.  Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene , 1990, Molecular and cellular biology.

[212]  D. Granner,et al.  Cyclic AMP-dependent protein kinase regulates transcription of the phosphoenolpyruvate carboxykinase gene but not binding of nuclear factors to the cyclic AMP regulatory element , 1990, Molecular and cellular biology.

[213]  H. Ishitsuka,et al.  Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. , 1990, Cancer research.

[214]  J. Fischer,et al.  Corticosterone alone does not explain increased muscle proteolysis in septic rats. , 1990, The Journal of surgical research.

[215]  J. Drouin,et al.  Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription , 1989, Molecular and cellular biology.

[216]  M. Falduto,et al.  Antagonism by glucocorticoids and exercise on expression of glutamine synthetase in skeletal muscle , 1989 .

[217]  W. Roesler,et al.  Identification of multiple protein binding domains in the promoter-regulatory region of the phosphoenolpyruvate carboxykinase (GTP) gene. , 1989, Journal of Biological Chemistry.

[218]  A. Hernández,et al.  Intracytoplasmic triglyceride accumulation produced by dexamethasone in adult rat hepatocytes cultivated on 3T3 cells. , 1988, Toxicology.

[219]  R. Garland Effect of insulin on the induction by dexamethasone of glucose-6-phosphohydrolase and translocase activities in cultured hepatoma cells. , 1988, Biochemical and biophysical research communications.

[220]  J. Gelin,et al.  Tumor-host wasting not explained by adrenal hyperfunction in tumor-bearing animals. , 1987, Journal of the National Cancer Institute.

[221]  J. Drouin,et al.  Tissue-specific regulation of pituitary proopiomelanocortin gene transcription by corticotropin-releasing hormone, 3',5'-cyclic adenosine monophosphate, and glucocorticoids. , 1987, Molecular endocrinology.

[222]  W. Ettinger,et al.  Effect of short-term, low-dose corticosteroids on plasma lipoprotein lipids. , 1987, Atherosclerosis.

[223]  R. Garland Induction of glucose 6-phosphatase in cultured hepatoma cells by dexamethasone. , 1986, Biochemical and biophysical research communications.

[224]  N. Wong,et al.  Multihormonal regulation and kinetics of induction of a hepatic mRNA sequence which is slowly responsive to triiodothyronine. , 1986, The Journal of biological chemistry.

[225]  A. Wynshaw-Boris,et al.  Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains. , 1986, The Journal of biological chemistry.

[226]  M. Boguski,et al.  Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[227]  R. Hanson,et al.  Thyroid hormone regulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat liver. , 1985, Biochemistry.

[228]  J. Drouin,et al.  Opposite regulation of pro-opiomelanocortin gene transcription by glucocorticoids and CRH , 1985, Molecular and Cellular Endocrinology.

[229]  G. Bray,et al.  Muscle Protein Turnover in the Perfused Hindquarters of Lean and Genetically Obese-Diabetic (db/db) Mice , 1984, Diabetes.

[230]  H. Maegawa,et al.  In vitro effects of glucocorticoid on glucose transport in rat adipocytes: evidence of a post-receptor coupling defect in insulin action. , 1984, Journal of biochemistry.

[231]  G. Bray,et al.  Adrenalectomy reverses insulin resistance in muscle from obese (ob/ob) mice. , 1984, The American journal of physiology.

[232]  M. Taskinen,et al.  Plasma lipoproteins, lipolytic enzymes, and very low density lipoprotein triglyceride turnover in Cushing's syndrome. , 1983, The Journal of clinical endocrinology and metabolism.

[233]  J. Amatruda,et al.  The effects of glucocorticoids on insulin-stimulated lipogenesis in primary cultures of rat hepatocytes. , 1983, The Biochemical journal.

[234]  A. Mason,et al.  Cortisol and corticotrophin in burned patients. , 1982, The Journal of trauma.

[235]  L. Orci,et al.  Glucagon and the A cell: physiology and pathophysiology (first two parts). , 1981, The New England journal of medicine.

[236]  L. Orci,et al.  Glucagon and the A cell: physiology and pathophysiology (second of two parts). , 1981, The New England journal of medicine.

[237]  E. Shafrir,et al.  Origin and pattern of glucocorticoid-induced hyperlipidemia in rats. Dose-dependent bimodal changes in serum lipids and lipoproteins in relation to hepatic lipogenesis and tissue lipoprotein lipase activity. , 1981, Biochimica et biophysica acta.

[238]  R. Schaur,et al.  Tumor host relations , 1979, Journal of Cancer Research and Clinical Oncology.

[239]  D. Kioussis,et al.  Alterations in translatable messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) in rat liver cytosol during deinduction. , 1978, The Journal of biological chemistry.

[240]  R. Hanson,et al.  Messenger RNA for renal phosphoenolpyruvate carboxykinase (GTP). Its translation in a heterologous cell-free system and its regulation by glucocorticoids and by changes in acid-base balance. , 1977, The Journal of biological chemistry.

[241]  R. Hanson,et al.  Increase in level of functional messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) during induction by cyclic adenosine 3':5'-monophosphate. , 1977, The Journal of biological chemistry.

[242]  G. Roth,et al.  Reductions in glucocorticoid inhibition of glucose oxidation and presumptive glucocorticoid receptor content in rat adipocytes during aging. , 1976, Endocrinology.

[243]  O. Meyuhas,et al.  Glucocorticoids and the regulation of phosphoenolpyruvate carboxykinase (guanosine triphosphate) in the rat. , 1975, The Biochemical journal.

[244]  R. Hanson,et al.  The regulation of phosphoenolpyruvate carboxykinase (GTP) synthesis in rat kidney cortex. The role of acid-base balance and glucocorticoids. , 1975, The Journal of biological chemistry.

[245]  S. Tilghman,et al.  Deinduction of phosphoenolpyruvate carboxykinase (guanosine triphosphate) synthesis in Reuber H-35 cells. , 1975, The Journal of biological chemistry.

[246]  E. Shafrir,et al.  Modulation of the activity of insulin-dependent enzymes of lipogenesis by glucocorticoids. , 1975, European journal of biochemistry.

[247]  J. Volpe,et al.  Hormonal regulation of fatty acid synthetase, acetyl-CoA carboxylase and fatty acid synthesis in mammalian adipose tissue and liver. , 1975, Biochimica et biophysica acta.

[248]  S. Tilghman,et al.  Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase during glucose repression in liver. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[249]  R. Pariente,et al.  Cushing's Syndrome , 1944, Definitions.

[250]  D. Attaix,et al.  Myostatin Gene Deletion Prevents Glucocorticoid- Induced Muscle Atrophy , 2022 .

[251]  Wei Wei,et al.  Dexamethasone-induced protein degradation in cultured myotubes is p300/HAT dependent. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

[252]  F. Gonzalez,et al.  Apolipoprotein A-IV is regulated by nutritional and metabolic stress: involvement of glucocorticoids, HNF-4 alpha, and PGC-1 alpha. , 2006, Journal of lipid research.

[253]  C. Corporeau,et al.  Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats. , 2006, American journal of physiology. Endocrinology and metabolism.

[254]  M. Maltoni,et al.  Progestagens and Corticosteroids in the Management Cancer Cachexia , 2006 .

[255]  S. Anker,et al.  Cachexia and Wasting: A Modern Approach , 2006 .

[256]  Richard R Almon,et al.  Temporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscle. , 2005, The Journal of endocrinology.

[257]  S. Shoelson,et al.  Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. , 2005, Nature medicine.

[258]  T. Friedman,et al.  Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice. , 2005, Diabetes.

[259]  V. Achard,et al.  Postnatal diet-induced obesity in rats upregulates systemic and adipose tissue glucocorticoid metabolism during development and in adulthood: its relationship with the metabolic syndrome. , 2005, Diabetes.

[260]  K. Kadota,et al.  Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver. , 2005, DNA research : an international journal for rapid publication of reports on genes and genomes.

[261]  Marc Montminy,et al.  PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. , 2004, Nature medicine.

[262]  B. Walker,et al.  Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue. , 2004, Recent progress in hormone research.

[263]  P. Puigserver,et al.  Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis. , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[264]  J. K. Oeser,et al.  Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells. , 2003, The Biochemical journal.

[265]  Jerry Donovan,et al.  Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. , 2003, Nature.

[266]  Liping Wei,et al.  Adrenalectomy enhances the insulin sensitivity of muscle protein synthesis. , 2003, American journal of physiology. Endocrinology and metabolism.

[267]  H. J. Harris,et al.  Intracellular regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11beta-HSD-1-deficient mice. , 2001, Endocrinology.

[268]  B. Walker,et al.  Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action. , 2001, Endocrinology.

[269]  B. Walker,et al.  Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors. , 2001, The Journal of clinical endocrinology and metabolism.

[270]  H. J. Harris,et al.  Intracellular Regeneration of Glucocorticoids by 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-1 Plays a Key Role in Regulation of the Hypothalamic-Pituitary-Adrenal Axis: Analysis of 11β-HSD-1-Deficient Mice1 , 2001 .

[271]  B. Walker,et al.  Understanding the role of glucocorticoids in obesity , 2000 .

[272]  A. Goldberg,et al.  Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. , 1999, The Journal of nutrition.

[273]  P. Puigserver,et al.  Activation of PPARgamma coactivator-1 through transcription factor docking. , 1999, Science.

[274]  J. Daly,et al.  Glucocorticoid blockade does not abrogate tumor-induced cachexia. , 1999, Nutrition and cancer.

[275]  J. Fischer,et al.  Counter-regulatory hormones and mechanisms in amino acid metabolism with special reference to the catabolic response in skeletal muscle. , 1999, Current opinion in clinical nutrition and metabolic care.

[276]  C. Wilson,et al.  Dexamethasone inhibits insulin-stimulated recruitment of GLUT4 to the cell surface in rat skeletal muscle. , 1998, Metabolism: clinical and experimental.

[277]  R. Hanson,et al.  Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. , 1997, Annual review of biochemistry.

[278]  D. Granner,et al.  Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells: opposite effects of dexamethasone and isoprenaline on transcription. , 1995, The Biochemical journal.

[279]  A. Srivastava,et al.  Effect of hypercorticism on regulation of skeletal muscle glycogen metabolism by insulin. , 1992, The American journal of physiology.

[280]  D. Granner,et al.  Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. , 1992, Annual review of physiology.

[281]  E. Mangiapane,et al.  Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes. , 1986, The Biochemical journal.

[282]  T. Cole,et al.  Effects of adrenalectomy and dexamethasone on hepatic lipid metabolism. , 1982, Journal of lipid research.

[283]  N. Haddad,et al.  [Addison's disease]. , 1973, La Tunisie medicale.