Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.
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Takao Hayakawa | Hiroyuki Mizuguchi | H. Mizuguchi | T. Hayakawa | F. Sakurai | K. Katayama | K. Kawabata | Kazuo Takayama | Kenji Kawabata | Katsuhisa Tashiro | Fuminori Sakurai | Miho Kusuda Furue | Akihisa Nonaka | Mitsuru Inamura | Kazufumi Katayama | Maiko Higuchi | Aki Nonaka | M. Furue | Kazuo Takayama | K. Tashiro | Maiko Higuchi | Mitsuru Inamura
[1] Hidenori Akutsu,et al. Mesenchymal to embryonic incomplete transition of human cells by chimeric OCT4/3 (POU5F1) with physiological co-activator EWS. , 2009, Experimental cell research.
[2] S. Duncan,et al. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. , 2000, Genes & development.
[3] F. Tronche,et al. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. , 2009, Gastroenterology.
[4] S. Yamanaka,et al. Efficient reprogramming of human and mouse primary extra‐embryonic cells to pluripotent stem cells , 2009, Genes to cells : devoted to molecular & cellular mechanisms.
[5] J. Maizel,et al. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. , 1974, Virology.
[6] K. Kinzler,et al. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. , 1995, Genes & development.
[7] M. Zern,et al. Differentiation and Characterization of Metabolically Functioning Hepatocytes from Human Embryonic Stem Cells , 2010, Stem cells.
[8] L. Hui,et al. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors , 2011, Nature.
[9] Gordon Keller,et al. Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development , 2008, Cell.
[10] H. Mizuguchi,et al. Generation of fiber‐modified adenovirus vectors containing heterologous peptides in both the HI loop and C terminus of the fiber knob , 2003, The journal of gene medicine.
[11] Hidenori Akutsu,et al. Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.
[12] M. Kay,et al. A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors. , 1999, Human gene therapy.
[13] J. Darnell,et al. Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[14] H. Mizuguchi,et al. Efficient gene transfer into mouse embryonic stem cells with adenovirus vectors. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[15] B. Hogan,et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. , 1996, Development.
[16] A. Mukhopadhyay,et al. Hepatocyte Nuclear Factor-4α Induces Transdifferentiation of Hematopoietic Cells into Hepatocytes , 2009, The Journal of Biological Chemistry.
[17] G. Konopka,et al. Junctional Adhesion Molecule-A Is Critical for the Formation of Pseudocanaliculi and Modulates E-cadherin Expression in Hepatic Cells* , 2007, Journal of Biological Chemistry.
[18] Jerrold M. Ward,et al. Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis , 2001, Molecular and Cellular Biology.
[19] M. Osanai,et al. Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization. , 2005, Experimental cell research.
[20] M. Kay,et al. Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. , 1998, Human gene therapy.
[21] M S German,et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. , 1998, Development.
[22] N. Shiojiri. Enzymo- and immunocytochemical analyses of the differentiation of liver cells in the prenatal mouse. , 1981, Journal of embryology and experimental morphology.
[23] M. Takeichi,et al. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. , 1987, Developmental biology.
[24] P. Andrews,et al. Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium , 2008, Proceedings of the National Academy of Sciences.
[25] Sayaka Sekiya,et al. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors , 2011, Nature.
[26] G. Konopka,et al. Hepatocyte nuclear factor 4 (cid:1) orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver , 2006 .
[27] J. Thomson,et al. Embryonic stem cell lines derived from human blastocysts. , 1998, Science.
[28] H. Mizuguchi,et al. Approaches to improving the kinetics of adenovirus-delivered genes and gene products. , 2005, Advanced drug delivery reviews.
[29] J. Adamson,et al. Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis , 2003, Nature Genetics.
[30] Raghu Kalluri,et al. The epithelial–mesenchymal transition: new insights in signaling, development, and disease , 2006, The Journal of cell biology.
[31] Xiu-Sheng Miao,et al. Determination of carbamazepine and its metabolites in aqueous samples using liquid chromatography-electrospray tandem mass spectrometry. , 2003, Analytical chemistry.
[32] H. Mizuguchi,et al. Efficient and Directive Generation of Two Distinct Endoderm Lineages from Human ESCs and iPSCs by Differentiation Stage-Specific SOX17 Transduction , 2011, PloS one.
[33] C. Wolf,et al. Inactivation of the Hepatic Cytochrome P450 System by Conditional Deletion of Hepatic Cytochrome P450 Reductase* , 2003, The Journal of Biological Chemistry.
[34] Stephen Dalton,et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells , 2010, Hepatology.
[35] N. Shiojiri. The origin of intrahepatic bile duct cells in the mouse. , 1984, Journal of embryology and experimental morphology.
[36] A. Cederbaum,et al. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. , 1995, The Journal of pharmacology and experimental therapeutics.
[37] Benjamin Geiger,et al. The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells , 1982, Cell.
[38] Nicola J. Rinaldi,et al. Control of Pancreas and Liver Gene Expression by HNF Transcription Factors , 2004, Science.
[39] H. Deng,et al. Derivation and Characterization of Hepatic Progenitor Cells from Human Embryonic Stem Cells , 2009, PloS one.
[40] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[41] P. Anzenbacher,et al. Cytochromes P450 and metabolism of xenobiotics , 2001, Cellular and Molecular Life Sciences CMLS.
[42] Alejandro Soto-Gutiérrez,et al. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. , 2009, Gastroenterology.
[43] Gavin Kelsey,et al. Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis , 1994, Mechanisms of Development.
[44] Y. Nakajima,et al. In Vitro Differentiation of Embryonic Stem Cells into Hepatocyte‐Like Cells Identified by Cellular Uptake of Indocyanine Green , 2002, Stem cells.
[45] H. Moriwaki,et al. Differentiation of Mouse Hepatic Progenitor Cells Induced by Hepatocyte Nuclear Factor-4 and Cell Transplantation in Mice With Liver Fibrosis , 2008, Transplantation.
[46] R. Pedersen,et al. Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development , 2010, Hepatology.
[47] Martyn T. Smith,et al. Mechanisms of troglitazone hepatotoxicity. , 2003, Chemical research in toxicology.
[48] H. Mizuguchi,et al. Efficient adenovirus vector‐mediated PPAR gamma gene transfer into mouse embryoid bodies promotes adipocyte differentiation , 2008, The journal of gene medicine.
[49] M. Ingelman-Sundberg,et al. Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment. , 1999, Trends in pharmacological sciences.
[50] G. F. Weber,et al. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. , 1993, Cancer research.