Transmission Electron Microscopy

Samples should be submitted formalin fixed. Preferably we would like to get a larger, approximately 3 cm in diameter, well fixed tissue sample, together with a detailed report of the clinical presentation, gross, and microscopic lesions. We will cut submitted sections (fig. 3), paraffin embed one half of the tissue to produce an H&E slide and use this slide to identify the best location for further ultrastructural examination (fig. 4) by comparing the microscopic tissue half with the mirror image of the remaining formalin fixed tissue. For each submission, we will then cut 4 trapezoid 2-3 mm tissue samples (fig. 5) to produce plastic embedded “thick” sections (fig. 6). We also accept the submission of samples prepared in a similar manner by the client for processing. For each case, 2 “thin” sections will be produced and examined by our team of highly experienced pathologists. Refer to our Fee Schedule or Available Tests link on our website for current pricing. For more information on the Transmission Electron Microscopy, contact Dr. Matti Kiupel at 517-353-5275. 1