Synthetic studies on duocarmycin. 1. Total synthesis of dl-duocarmycin A and its 2-epimer
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[1] D. Boger,et al. Total synthesis and preliminary evaluation of (+)- and ent-(−)-duocarmycin SA , 1993 .
[2] D. Boger. Design, synthesis, and evaluation of DNA minor groove binding agents , 1993 .
[3] D. Boger,et al. Total synthesis of (+)-duocarmycin SA , 1992 .
[4] D. Patel,et al. Site-specific covalent duocarmycin A-intramolecular DNA triplex complex , 1992 .
[5] K. Nakatani,et al. Synthesis and cytotoxicity of enantiomeric pairs of duocarmycin a and its 2-epimer , 1992 .
[6] H. Nakano,et al. Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production. , 1991, The Journal of antibiotics.
[7] H. Sano,et al. Structure of duocarmycin SA, a potent antitumor antibiotic. , 1991, The Journal of antibiotics.
[8] D. Boger,et al. Duocarmycin-pyrindamycin DNA alkylation properties and identification, synthesis, and evaluation of agents incorporating the pharmacophore of the duocarmycin-pyrindamycin alkylation subunit. Identification of the CC-1065 duocarmycin common pharmacophore , 1990 .
[9] I. Kawamoto,et al. Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp. , 1990, The Journal of antibiotics.
[10] R. S. Coleman,et al. Synthesis and evaluation of aborted and extended CC-1065 functional analogs: (+)- and (-)-CPI-PDE-I1, (+)- and (-)-CPI-CDPI1, and (.+-.)-, (+)-, and (-)-CPI-CDPI3. Preparation of key partial structures and definition of an additional functional role of the CC-1065 central and right-hand subunits , 1990 .
[11] M. Warpehoski,et al. Sequence Specificity of DNA Alkylation by the Unnatural Enantiomer of CC-1065 and Its Synthetic Analogues , 1990 .
[12] H. Sugiyama,et al. Covalent alkylation of DNA with duocarmycin A. Identification of abasic site structure. , 1990, Tetrahedron letters.
[13] H. Yamamoto,et al. Antitumor activity of pyrindamycins A and B. , 1989, The Journal of antibiotics.
[14] M. Morimoto,et al. New antitumor antibiotics, duocarmycins B1 and B2. , 1989, The Journal of antibiotics.
[15] K. Asano,et al. Duocarmycin A, a new antitumor antibiotic from Streptomyces. , 1988, The Journal of antibiotics.
[16] H. Sano,et al. Structures of duocarmycins, novel antitumor antibiotics produced by Streptomyces sp. , 1988, Chemical & pharmaceutical bulletin.
[17] K. Asano,et al. DC89-A1, a new antitumor antibiotic from Streptomyces. , 1988, The Journal of antibiotics.
[18] W. C. Krueger,et al. Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065. , 1988, Journal of medicinal chemistry.
[19] Paul D. Johnson,et al. Coupling of cyclopropapyrroloindole (CPI) derivatives. The preparation of CC-1065, ent-CC-1065, and analogs , 1987 .
[20] M. Cava,et al. Review of synthetic studies toward CC-1065, PDE-I, and PDE-II , 1987 .
[21] M. Warpehoski. Total synthesis of U- 71,184, s potent new antitumor agent modeled on cc-1065 , 1986 .
[22] C. Moody,et al. Synthesis of the phosphodiesterase inhibitors PDE-I and PDE-II , 1985 .
[23] G. L. Clarke,et al. Preliminary toxicity studies with the DNA-binding antibiotic, CC-1065. , 1984, The Journal of antibiotics.
[24] M. Warpehoski,et al. A versatile and efficient process to 3-substituted indoles from anilines , 1983 .
[25] W. C. Krueger,et al. The structure of CC-1065, a potent antitumor agent and its binding to DNA , 1981 .
[26] W. Wierenga. Synthesis of the left-hand segment of the antitumor agent CC-1065 , 1981 .
[27] C. Chidester,et al. Structure of CC-1065 (NSC-298223), a new antitumor antibiotic. , 1980, The Journal of antibiotics.
[28] P. G. Gassman,et al. Generation of azasulfonium salts from halogen-sulfide complexes and anilines. Synthesis of indoles, oxindoles, and alkylated aromatic amines bearing cation stabilizing substituents , 1974 .
[29] S. Winstein,et al. Neighboring Carbon and Hydrogen. Li. Dienones from Ar1[UNK]-3 Participation. Isolation and Behavior of Spiro(2,5)octa-1,4-diene-3-one , 1963 .
[30] O. Neunhoeffer,et al. Zum Indolonproblem, I. Synthese in 2‐Stellung substituierter Derivate des Indolons‐(3) Ein Fall alkoholytischer Ketonspaltung , 1961 .